| Full name: adenosine deaminase tRNA specific 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 23536 | HGNC ID: HGNC:228 | Ensembl Gene: ENSG00000065457 | OMIM ID: 604230 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAT1 | 23536 | 219384_s_at | 0.6758 | 0.2428 | |
| GSE20347 | ADAT1 | 23536 | 219384_s_at | 0.3644 | 0.0169 | |
| GSE23400 | ADAT1 | 23536 | 219384_s_at | 0.5124 | 0.0000 | |
| GSE26886 | ADAT1 | 23536 | 219384_s_at | 0.6547 | 0.0003 | |
| GSE29001 | ADAT1 | 23536 | 219384_s_at | 0.5659 | 0.0159 | |
| GSE38129 | ADAT1 | 23536 | 219384_s_at | 0.5317 | 0.0002 | |
| GSE45670 | ADAT1 | 23536 | 219384_s_at | 0.5936 | 0.0001 | |
| GSE53622 | ADAT1 | 23536 | 84184 | 0.7966 | 0.0000 | |
| GSE53624 | ADAT1 | 23536 | 84184 | 0.6371 | 0.0000 | |
| GSE63941 | ADAT1 | 23536 | 219384_s_at | -0.1796 | 0.7535 | |
| GSE77861 | ADAT1 | 23536 | 219384_s_at | 0.2891 | 0.0879 | |
| GSE97050 | ADAT1 | 23536 | A_23_P141100 | 0.4660 | 0.1978 | |
| SRP007169 | ADAT1 | 23536 | RNAseq | 1.0508 | 0.0122 | |
| SRP008496 | ADAT1 | 23536 | RNAseq | 1.2923 | 0.0000 | |
| SRP064894 | ADAT1 | 23536 | RNAseq | 0.5030 | 0.0048 | |
| SRP133303 | ADAT1 | 23536 | RNAseq | 0.4984 | 0.0000 | |
| SRP159526 | ADAT1 | 23536 | RNAseq | 0.5320 | 0.0025 | |
| SRP193095 | ADAT1 | 23536 | RNAseq | 0.3419 | 0.0006 | |
| SRP219564 | ADAT1 | 23536 | RNAseq | 0.5073 | 0.0358 | |
| TCGA | ADAT1 | 23536 | RNAseq | 0.0735 | 0.2229 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ADAT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAT1 | 23536 | 5 | 0 | 25 | |
| GSE20123 | ADAT1 | 23536 | 5 | 0 | 25 | |
| GSE43470 | ADAT1 | 23536 | 2 | 7 | 34 | |
| GSE46452 | ADAT1 | 23536 | 37 | 2 | 20 | |
| GSE47630 | ADAT1 | 23536 | 11 | 8 | 21 | |
| GSE54993 | ADAT1 | 23536 | 2 | 4 | 64 | |
| GSE54994 | ADAT1 | 23536 | 8 | 10 | 35 | |
| GSE60625 | ADAT1 | 23536 | 4 | 0 | 7 | |
| GSE74703 | ADAT1 | 23536 | 2 | 5 | 29 | |
| GSE74704 | ADAT1 | 23536 | 2 | 0 | 18 | |
| TCGA | ADAT1 | 23536 | 24 | 15 | 57 |
Total number of gains: 102; Total number of losses: 51; Total Number of normals: 335.
Somatic mutations of ADAT1:
Generating mutation plots.
Highly correlated genes for ADAT1:
Showing top 20/1753 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAT1 | SORD | 0.748994 | 3 | 0 | 3 |
| ADAT1 | CHCHD6 | 0.746804 | 3 | 0 | 3 |
| ADAT1 | CYB5R1 | 0.744099 | 3 | 0 | 3 |
| ADAT1 | SUZ12 | 0.743408 | 3 | 0 | 3 |
| ADAT1 | C1orf226 | 0.740063 | 3 | 0 | 3 |
| ADAT1 | DOCK7 | 0.737801 | 4 | 0 | 3 |
| ADAT1 | ELOF1 | 0.735072 | 3 | 0 | 3 |
| ADAT1 | CMC1 | 0.734607 | 3 | 0 | 3 |
| ADAT1 | SLC35B2 | 0.733956 | 3 | 0 | 3 |
| ADAT1 | RICTOR | 0.733098 | 3 | 0 | 3 |
| ADAT1 | UBR1 | 0.730873 | 3 | 0 | 3 |
| ADAT1 | PMS2 | 0.726656 | 3 | 0 | 3 |
| ADAT1 | NANP | 0.722199 | 3 | 0 | 3 |
| ADAT1 | SPATA5 | 0.720797 | 5 | 0 | 5 |
| ADAT1 | RTN4IP1 | 0.720281 | 5 | 0 | 4 |
| ADAT1 | CDC123 | 0.719191 | 4 | 0 | 3 |
| ADAT1 | C7orf50 | 0.715176 | 3 | 0 | 3 |
| ADAT1 | ARL6IP6 | 0.715002 | 6 | 0 | 6 |
| ADAT1 | DTX3L | 0.714241 | 4 | 0 | 4 |
| ADAT1 | BRMS1L | 0.713844 | 3 | 0 | 3 |
For details and further investigation, click here
