| Full name: deleted in primary ciliary dyskinesia homolog (mouse) | Alias Symbol: DKFZP566F084|RP11-529I10.4 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 25911 | HGNC ID: HGNC:24542 | Ensembl Gene: ENSG00000166171 | OMIM ID: 616467 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DPCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPCD | 25911 | 226009_at | -0.1301 | 0.8800 | |
| GSE26886 | DPCD | 25911 | 226009_at | -0.7168 | 0.0006 | |
| GSE45670 | DPCD | 25911 | 226009_at | -0.1453 | 0.3412 | |
| GSE53622 | DPCD | 25911 | 18313 | -0.1854 | 0.0623 | |
| GSE53624 | DPCD | 25911 | 25806 | -0.1887 | 0.0109 | |
| GSE63941 | DPCD | 25911 | 226009_at | 0.1335 | 0.7931 | |
| GSE77861 | DPCD | 25911 | 226009_at | -0.4234 | 0.0693 | |
| GSE97050 | DPCD | 25911 | A_33_P3240200 | 0.0823 | 0.7206 | |
| SRP007169 | DPCD | 25911 | RNAseq | -0.3873 | 0.5455 | |
| SRP064894 | DPCD | 25911 | RNAseq | -0.1561 | 0.6020 | |
| SRP133303 | DPCD | 25911 | RNAseq | -0.3270 | 0.1138 | |
| SRP159526 | DPCD | 25911 | RNAseq | -0.1430 | 0.5563 | |
| SRP193095 | DPCD | 25911 | RNAseq | -0.4414 | 0.0009 | |
| SRP219564 | DPCD | 25911 | RNAseq | -0.4711 | 0.1349 | |
| TCGA | DPCD | 25911 | RNAseq | 0.1268 | 0.1811 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DPCD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPCD | 25911 | 2 | 9 | 19 | |
| GSE20123 | DPCD | 25911 | 2 | 8 | 20 | |
| GSE43470 | DPCD | 25911 | 0 | 8 | 35 | |
| GSE46452 | DPCD | 25911 | 0 | 11 | 48 | |
| GSE47630 | DPCD | 25911 | 2 | 14 | 24 | |
| GSE54993 | DPCD | 25911 | 8 | 0 | 62 | |
| GSE54994 | DPCD | 25911 | 1 | 12 | 40 | |
| GSE60625 | DPCD | 25911 | 0 | 0 | 11 | |
| GSE74703 | DPCD | 25911 | 0 | 5 | 31 | |
| GSE74704 | DPCD | 25911 | 1 | 4 | 15 | |
| TCGA | DPCD | 25911 | 5 | 28 | 63 |
Total number of gains: 21; Total number of losses: 99; Total Number of normals: 368.
Somatic mutations of DPCD:
Generating mutation plots.
Highly correlated genes for DPCD:
Showing top 20/431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPCD | BCAS1 | 0.74746 | 3 | 0 | 3 |
| DPCD | STX10 | 0.741419 | 3 | 0 | 3 |
| DPCD | TRAPPC8 | 0.725457 | 3 | 0 | 3 |
| DPCD | CHID1 | 0.71909 | 3 | 0 | 3 |
| DPCD | ABHD16A | 0.713037 | 3 | 0 | 3 |
| DPCD | SRP68 | 0.711221 | 3 | 0 | 3 |
| DPCD | RBM6 | 0.70705 | 3 | 0 | 3 |
| DPCD | PUS7L | 0.706613 | 3 | 0 | 3 |
| DPCD | CD63 | 0.70657 | 3 | 0 | 3 |
| DPCD | SLC2A10 | 0.703088 | 3 | 0 | 3 |
| DPCD | AKIRIN1 | 0.700257 | 3 | 0 | 3 |
| DPCD | MSL3 | 0.697968 | 3 | 0 | 3 |
| DPCD | TMEM186 | 0.695886 | 3 | 0 | 3 |
| DPCD | C1orf122 | 0.679998 | 3 | 0 | 3 |
| DPCD | TSPAN5 | 0.677464 | 3 | 0 | 3 |
| DPCD | BTAF1 | 0.673891 | 4 | 0 | 4 |
| DPCD | MRPS7 | 0.669181 | 3 | 0 | 3 |
| DPCD | PPID | 0.661848 | 3 | 0 | 3 |
| DPCD | PHYHD1 | 0.661424 | 3 | 0 | 3 |
| DPCD | PRKCH | 0.661292 | 5 | 0 | 5 |
For details and further investigation, click here
