| Full name: mitochondrial ribosomal protein S7 | Alias Symbol: MRP-S|RP-S7|RPMS7 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 51081 | HGNC ID: HGNC:14499 | Ensembl Gene: ENSG00000125445 | OMIM ID: 611974 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS7 | 51081 | 217932_at | 0.1703 | 0.6824 | |
| GSE20347 | MRPS7 | 51081 | 217932_at | -0.0387 | 0.8503 | |
| GSE23400 | MRPS7 | 51081 | 217932_at | 0.1681 | 0.0174 | |
| GSE26886 | MRPS7 | 51081 | 217932_at | -0.4871 | 0.0010 | |
| GSE29001 | MRPS7 | 51081 | 217932_at | -0.0081 | 0.9842 | |
| GSE38129 | MRPS7 | 51081 | 217932_at | 0.1252 | 0.3779 | |
| GSE45670 | MRPS7 | 51081 | 217932_at | 0.0858 | 0.6356 | |
| GSE53622 | MRPS7 | 51081 | 135525 | 0.3460 | 0.0000 | |
| GSE53624 | MRPS7 | 51081 | 135525 | 0.2906 | 0.0000 | |
| GSE63941 | MRPS7 | 51081 | 217932_at | 0.8130 | 0.0221 | |
| GSE77861 | MRPS7 | 51081 | 217932_at | 0.2192 | 0.3030 | |
| GSE97050 | MRPS7 | 51081 | A_23_P3979 | -0.1064 | 0.7449 | |
| SRP007169 | MRPS7 | 51081 | RNAseq | 0.0031 | 0.9934 | |
| SRP008496 | MRPS7 | 51081 | RNAseq | -0.1760 | 0.4471 | |
| SRP064894 | MRPS7 | 51081 | RNAseq | 0.3052 | 0.1891 | |
| SRP133303 | MRPS7 | 51081 | RNAseq | 0.4623 | 0.0284 | |
| SRP159526 | MRPS7 | 51081 | RNAseq | 0.2624 | 0.2148 | |
| SRP193095 | MRPS7 | 51081 | RNAseq | -0.2115 | 0.0870 | |
| SRP219564 | MRPS7 | 51081 | RNAseq | 0.2357 | 0.5129 | |
| TCGA | MRPS7 | 51081 | RNAseq | 0.0521 | 0.3002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS7 | 51081 | 6 | 2 | 22 | |
| GSE20123 | MRPS7 | 51081 | 6 | 2 | 22 | |
| GSE43470 | MRPS7 | 51081 | 5 | 3 | 35 | |
| GSE46452 | MRPS7 | 51081 | 33 | 0 | 26 | |
| GSE47630 | MRPS7 | 51081 | 8 | 1 | 31 | |
| GSE54993 | MRPS7 | 51081 | 2 | 5 | 63 | |
| GSE54994 | MRPS7 | 51081 | 10 | 4 | 39 | |
| GSE60625 | MRPS7 | 51081 | 6 | 0 | 5 | |
| GSE74703 | MRPS7 | 51081 | 5 | 1 | 30 | |
| GSE74704 | MRPS7 | 51081 | 4 | 1 | 15 | |
| TCGA | MRPS7 | 51081 | 32 | 10 | 54 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of MRPS7:
Generating mutation plots.
Highly correlated genes for MRPS7:
Showing top 20/543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS7 | CLEC16A | 0.767029 | 3 | 0 | 3 |
| MRPS7 | MCU | 0.76387 | 3 | 0 | 3 |
| MRPS7 | PITHD1 | 0.753139 | 3 | 0 | 3 |
| MRPS7 | PIGN | 0.749285 | 3 | 0 | 3 |
| MRPS7 | MRPL38 | 0.743829 | 5 | 0 | 4 |
| MRPS7 | LSM1 | 0.743666 | 3 | 0 | 3 |
| MRPS7 | SUMO2 | 0.737287 | 3 | 0 | 3 |
| MRPS7 | HAUS6 | 0.734117 | 3 | 0 | 3 |
| MRPS7 | CETN2 | 0.725152 | 4 | 0 | 4 |
| MRPS7 | MYO1E | 0.712576 | 3 | 0 | 3 |
| MRPS7 | XPO1 | 0.705573 | 4 | 0 | 4 |
| MRPS7 | COPS7A | 0.702946 | 5 | 0 | 5 |
| MRPS7 | ATXN7L3B | 0.696318 | 4 | 0 | 3 |
| MRPS7 | GLYR1 | 0.695765 | 4 | 0 | 4 |
| MRPS7 | PDIK1L | 0.695579 | 3 | 0 | 3 |
| MRPS7 | TSEN54 | 0.692374 | 4 | 0 | 4 |
| MRPS7 | NDUFV2 | 0.690876 | 3 | 0 | 3 |
| MRPS7 | HEXIM1 | 0.684147 | 3 | 0 | 3 |
| MRPS7 | PPP1R7 | 0.674983 | 3 | 0 | 3 |
| MRPS7 | CTCF | 0.674644 | 5 | 0 | 4 |
For details and further investigation, click here
