| Full name: CD63 molecule | Alias Symbol: ME491|TSPAN30 | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 967 | HGNC ID: HGNC:1692 | Ensembl Gene: ENSG00000135404 | OMIM ID: 155740 |
| Drug and gene relationship at DGIdb | |||
CD63 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05205 | Proteoglycans in cancer |
Expression of CD63:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD63 | 967 | 200663_at | -0.2030 | 0.4053 | |
| GSE20347 | CD63 | 967 | 200663_at | -0.2211 | 0.0898 | |
| GSE23400 | CD63 | 967 | 200663_at | -0.0818 | 0.2337 | |
| GSE26886 | CD63 | 967 | 200663_at | -0.8953 | 0.0004 | |
| GSE29001 | CD63 | 967 | 200663_at | -0.7156 | 0.1161 | |
| GSE38129 | CD63 | 967 | 200663_at | -0.1876 | 0.2545 | |
| GSE45670 | CD63 | 967 | 200663_at | -0.3628 | 0.0003 | |
| GSE53622 | CD63 | 967 | 20562 | -0.2380 | 0.0001 | |
| GSE53624 | CD63 | 967 | 20562 | -0.1714 | 0.0008 | |
| GSE63941 | CD63 | 967 | 200663_at | -1.4697 | 0.0018 | |
| GSE77861 | CD63 | 967 | 200663_at | -0.2255 | 0.1130 | |
| GSE97050 | CD63 | 967 | A_24_P270144 | -0.1633 | 0.5146 | |
| SRP007169 | CD63 | 967 | RNAseq | -0.8192 | 0.0501 | |
| SRP008496 | CD63 | 967 | RNAseq | -0.5711 | 0.0233 | |
| SRP064894 | CD63 | 967 | RNAseq | 0.0254 | 0.9370 | |
| SRP133303 | CD63 | 967 | RNAseq | 0.2372 | 0.0862 | |
| SRP159526 | CD63 | 967 | RNAseq | 0.3392 | 0.3687 | |
| SRP193095 | CD63 | 967 | RNAseq | -0.3663 | 0.0770 | |
| SRP219564 | CD63 | 967 | RNAseq | 0.3401 | 0.4689 | |
| TCGA | CD63 | 967 | RNAseq | -0.2175 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CD63 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD63:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD63 | 967 | 6 | 1 | 23 | |
| GSE20123 | CD63 | 967 | 6 | 1 | 23 | |
| GSE43470 | CD63 | 967 | 4 | 0 | 39 | |
| GSE46452 | CD63 | 967 | 8 | 1 | 50 | |
| GSE47630 | CD63 | 967 | 10 | 2 | 28 | |
| GSE54993 | CD63 | 967 | 0 | 5 | 65 | |
| GSE54994 | CD63 | 967 | 4 | 1 | 48 | |
| GSE60625 | CD63 | 967 | 0 | 0 | 11 | |
| GSE74703 | CD63 | 967 | 4 | 0 | 32 | |
| GSE74704 | CD63 | 967 | 4 | 1 | 15 | |
| TCGA | CD63 | 967 | 15 | 10 | 71 |
Total number of gains: 61; Total number of losses: 22; Total Number of normals: 405.
Somatic mutations of CD63:
Generating mutation plots.
Highly correlated genes for CD63:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD63 | GPIHBP1 | 0.774698 | 3 | 0 | 3 |
| CD63 | SNX25 | 0.774535 | 3 | 0 | 3 |
| CD63 | GALNT15 | 0.766309 | 3 | 0 | 3 |
| CD63 | ZNF583 | 0.762892 | 3 | 0 | 3 |
| CD63 | FNIP2 | 0.748931 | 3 | 0 | 3 |
| CD63 | PITHD1 | 0.745162 | 3 | 0 | 3 |
| CD63 | PDCD7 | 0.744056 | 3 | 0 | 3 |
| CD63 | RTN3 | 0.742835 | 3 | 0 | 3 |
| CD63 | MYCT1 | 0.732139 | 4 | 0 | 3 |
| CD63 | RNF185 | 0.7281 | 3 | 0 | 3 |
| CD63 | ACRBP | 0.727964 | 3 | 0 | 3 |
| CD63 | SYTL4 | 0.7272 | 6 | 0 | 5 |
| CD63 | KDM5D | 0.725348 | 3 | 0 | 3 |
| CD63 | MAGI2-AS3 | 0.721116 | 4 | 0 | 3 |
| CD63 | PTPRB | 0.718774 | 4 | 0 | 3 |
| CD63 | PRPH2 | 0.716551 | 4 | 0 | 3 |
| CD63 | TXNL4A | 0.715628 | 3 | 0 | 3 |
| CD63 | KPNA6 | 0.714023 | 3 | 0 | 3 |
| CD63 | NDUFS3 | 0.71399 | 3 | 0 | 3 |
| CD63 | BBS4 | 0.710351 | 3 | 0 | 3 |
For details and further investigation, click here
