| Full name: akirin 1 | Alias Symbol: FLJ12666 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 79647 | HGNC ID: HGNC:25744 | Ensembl Gene: ENSG00000174574 | OMIM ID: 615164 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AKIRIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKIRIN1 | 79647 | 222459_at | -0.1830 | 0.6909 | |
| GSE20347 | AKIRIN1 | 79647 | 217893_s_at | -0.0789 | 0.7198 | |
| GSE23400 | AKIRIN1 | 79647 | 217893_s_at | -0.0058 | 0.9317 | |
| GSE26886 | AKIRIN1 | 79647 | 217893_s_at | -0.9826 | 0.0001 | |
| GSE29001 | AKIRIN1 | 79647 | 217893_s_at | -0.2258 | 0.5671 | |
| GSE38129 | AKIRIN1 | 79647 | 217893_s_at | -0.1890 | 0.3666 | |
| GSE45670 | AKIRIN1 | 79647 | 222459_at | 0.1210 | 0.4196 | |
| GSE53622 | AKIRIN1 | 79647 | 38251 | -0.0077 | 0.9295 | |
| GSE53624 | AKIRIN1 | 79647 | 35218 | 0.0557 | 0.6319 | |
| GSE63941 | AKIRIN1 | 79647 | 222459_at | -0.7620 | 0.1629 | |
| GSE77861 | AKIRIN1 | 79647 | 222459_at | -0.0027 | 0.9943 | |
| GSE97050 | AKIRIN1 | 79647 | A_23_P256148 | -0.2567 | 0.2778 | |
| SRP007169 | AKIRIN1 | 79647 | RNAseq | 0.3875 | 0.2653 | |
| SRP008496 | AKIRIN1 | 79647 | RNAseq | 0.4375 | 0.0618 | |
| SRP064894 | AKIRIN1 | 79647 | RNAseq | -0.3559 | 0.0567 | |
| SRP133303 | AKIRIN1 | 79647 | RNAseq | 0.4342 | 0.0115 | |
| SRP159526 | AKIRIN1 | 79647 | RNAseq | 0.0082 | 0.9762 | |
| SRP193095 | AKIRIN1 | 79647 | RNAseq | 0.0144 | 0.8974 | |
| SRP219564 | AKIRIN1 | 79647 | RNAseq | -0.4331 | 0.2998 | |
| TCGA | AKIRIN1 | 79647 | RNAseq | -0.1546 | 0.0028 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AKIRIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKIRIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKIRIN1 | 79647 | 3 | 4 | 23 | |
| GSE20123 | AKIRIN1 | 79647 | 2 | 3 | 25 | |
| GSE43470 | AKIRIN1 | 79647 | 7 | 2 | 34 | |
| GSE46452 | AKIRIN1 | 79647 | 4 | 1 | 54 | |
| GSE47630 | AKIRIN1 | 79647 | 8 | 4 | 28 | |
| GSE54993 | AKIRIN1 | 79647 | 0 | 1 | 69 | |
| GSE54994 | AKIRIN1 | 79647 | 13 | 2 | 38 | |
| GSE60625 | AKIRIN1 | 79647 | 0 | 0 | 11 | |
| GSE74703 | AKIRIN1 | 79647 | 6 | 1 | 29 | |
| GSE74704 | AKIRIN1 | 79647 | 1 | 0 | 19 | |
| TCGA | AKIRIN1 | 79647 | 15 | 16 | 65 |
Total number of gains: 59; Total number of losses: 34; Total Number of normals: 395.
Somatic mutations of AKIRIN1:
Generating mutation plots.
Highly correlated genes for AKIRIN1:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKIRIN1 | ARL1 | 0.808176 | 3 | 0 | 3 |
| AKIRIN1 | ARIH1 | 0.799183 | 3 | 0 | 3 |
| AKIRIN1 | SOCS2 | 0.779679 | 3 | 0 | 3 |
| AKIRIN1 | APPL1 | 0.74792 | 3 | 0 | 3 |
| AKIRIN1 | ZRANB1 | 0.739413 | 3 | 0 | 3 |
| AKIRIN1 | WEE1 | 0.738709 | 3 | 0 | 3 |
| AKIRIN1 | ZNF518A | 0.729994 | 3 | 0 | 3 |
| AKIRIN1 | SYTL4 | 0.72737 | 3 | 0 | 3 |
| AKIRIN1 | LAPTM4A | 0.727171 | 3 | 0 | 3 |
| AKIRIN1 | USP54 | 0.719181 | 3 | 0 | 3 |
| AKIRIN1 | TPRG1L | 0.718306 | 3 | 0 | 3 |
| AKIRIN1 | SORT1 | 0.715865 | 3 | 0 | 3 |
| AKIRIN1 | WDR77 | 0.715668 | 3 | 0 | 3 |
| AKIRIN1 | HTATSF1 | 0.714651 | 3 | 0 | 3 |
| AKIRIN1 | C2CD2 | 0.714457 | 3 | 0 | 3 |
| AKIRIN1 | ACADVL | 0.712452 | 3 | 0 | 3 |
| AKIRIN1 | ARMCX3 | 0.711014 | 3 | 0 | 3 |
| AKIRIN1 | PLEKHM1 | 0.705704 | 3 | 0 | 3 |
| AKIRIN1 | SKAP2 | 0.703026 | 3 | 0 | 3 |
| AKIRIN1 | UBE2D2 | 0.702474 | 3 | 0 | 3 |
For details and further investigation, click here
