| Full name: breast carcinoma amplified sequence 1 | Alias Symbol: NABC1|AIBC1 | ||
| Type: protein-coding gene | Cytoband: 20q13.2 | ||
| Entrez ID: 8537 | HGNC ID: HGNC:974 | Ensembl Gene: ENSG00000064787 | OMIM ID: 602968 |
| Drug and gene relationship at DGIdb | |||
Expression of BCAS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCAS1 | 8537 | 204378_at | -0.2065 | 0.9108 | |
| GSE20347 | BCAS1 | 8537 | 204378_at | -0.3349 | 0.2218 | |
| GSE23400 | BCAS1 | 8537 | 204378_at | -0.2834 | 0.0000 | |
| GSE26886 | BCAS1 | 8537 | 204378_at | -1.7895 | 0.0000 | |
| GSE29001 | BCAS1 | 8537 | 204378_at | -1.1598 | 0.0538 | |
| GSE38129 | BCAS1 | 8537 | 204378_at | -0.6261 | 0.0057 | |
| GSE45670 | BCAS1 | 8537 | 204378_at | -0.0355 | 0.9353 | |
| GSE53622 | BCAS1 | 8537 | 94854 | -2.5824 | 0.0000 | |
| GSE53624 | BCAS1 | 8537 | 94854 | -3.3289 | 0.0000 | |
| GSE63941 | BCAS1 | 8537 | 204378_at | 0.3418 | 0.6824 | |
| GSE77861 | BCAS1 | 8537 | 204378_at | -0.3355 | 0.0471 | |
| GSE97050 | BCAS1 | 8537 | A_33_P3330911 | -0.4564 | 0.4284 | |
| SRP007169 | BCAS1 | 8537 | RNAseq | -2.1072 | 0.0495 | |
| SRP008496 | BCAS1 | 8537 | RNAseq | -2.7130 | 0.0233 | |
| SRP064894 | BCAS1 | 8537 | RNAseq | -1.6527 | 0.0025 | |
| SRP133303 | BCAS1 | 8537 | RNAseq | -2.2901 | 0.0000 | |
| SRP159526 | BCAS1 | 8537 | RNAseq | -3.1875 | 0.0023 | |
| SRP193095 | BCAS1 | 8537 | RNAseq | -1.8490 | 0.0012 | |
| SRP219564 | BCAS1 | 8537 | RNAseq | -2.4358 | 0.0099 | |
| TCGA | BCAS1 | 8537 | RNAseq | -2.0034 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by BCAS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCAS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCAS1 | 8537 | 15 | 2 | 13 | |
| GSE20123 | BCAS1 | 8537 | 15 | 1 | 14 | |
| GSE43470 | BCAS1 | 8537 | 14 | 0 | 29 | |
| GSE46452 | BCAS1 | 8537 | 29 | 0 | 30 | |
| GSE47630 | BCAS1 | 8537 | 24 | 1 | 15 | |
| GSE54993 | BCAS1 | 8537 | 0 | 17 | 53 | |
| GSE54994 | BCAS1 | 8537 | 27 | 0 | 26 | |
| GSE60625 | BCAS1 | 8537 | 0 | 0 | 11 | |
| GSE74703 | BCAS1 | 8537 | 11 | 0 | 25 | |
| GSE74704 | BCAS1 | 8537 | 11 | 0 | 9 | |
| TCGA | BCAS1 | 8537 | 45 | 3 | 48 |
Total number of gains: 191; Total number of losses: 24; Total Number of normals: 273.
Somatic mutations of BCAS1:
Generating mutation plots.
Highly correlated genes for BCAS1:
Showing top 20/976 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCAS1 | ANKRD22 | 0.75785 | 3 | 0 | 3 |
| BCAS1 | PCBP1-AS1 | 0.74973 | 3 | 0 | 3 |
| BCAS1 | DPCD | 0.74746 | 3 | 0 | 3 |
| BCAS1 | TMEM234 | 0.739115 | 3 | 0 | 3 |
| BCAS1 | HIC2 | 0.737265 | 3 | 0 | 3 |
| BCAS1 | CAPN14 | 0.728099 | 5 | 0 | 5 |
| BCAS1 | SNX31 | 0.726688 | 6 | 0 | 5 |
| BCAS1 | NFYC | 0.72503 | 3 | 0 | 3 |
| BCAS1 | MUC20 | 0.721143 | 8 | 0 | 8 |
| BCAS1 | BCL2L15 | 0.714771 | 6 | 0 | 6 |
| BCAS1 | TMEM45B | 0.714692 | 6 | 0 | 6 |
| BCAS1 | UPK3B | 0.710806 | 3 | 0 | 3 |
| BCAS1 | ST6GALNAC1 | 0.70984 | 9 | 0 | 8 |
| BCAS1 | MAB21L3 | 0.708366 | 5 | 0 | 5 |
| BCAS1 | FAM3B | 0.707422 | 7 | 0 | 6 |
| BCAS1 | SMIM5 | 0.706425 | 5 | 0 | 5 |
| BCAS1 | SLC10A5 | 0.704347 | 3 | 0 | 3 |
| BCAS1 | C5orf66-AS1 | 0.702579 | 6 | 0 | 6 |
| BCAS1 | MPZL3 | 0.700812 | 5 | 0 | 5 |
| BCAS1 | CRB3 | 0.697004 | 5 | 0 | 5 |
For details and further investigation, click here
