| Full name: double PHD fingers 1 | Alias Symbol: neuro-d4|NEUD4|BAF45b | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 8193 | HGNC ID: HGNC:20225 | Ensembl Gene: ENSG00000011332 | OMIM ID: 601670 |
| Drug and gene relationship at DGIdb | |||
Expression of DPF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPF1 | 8193 | 206531_at | 0.1456 | 0.5181 | |
| GSE20347 | DPF1 | 8193 | 206531_at | 0.2639 | 0.0088 | |
| GSE23400 | DPF1 | 8193 | 206531_at | 0.0569 | 0.1547 | |
| GSE26886 | DPF1 | 8193 | 231599_x_at | 0.4398 | 0.0010 | |
| GSE29001 | DPF1 | 8193 | 206531_at | -0.3546 | 0.0261 | |
| GSE38129 | DPF1 | 8193 | 206531_at | 0.2396 | 0.0148 | |
| GSE45670 | DPF1 | 8193 | 231599_x_at | 0.3154 | 0.0137 | |
| GSE53622 | DPF1 | 8193 | 12920 | 0.8255 | 0.0000 | |
| GSE53624 | DPF1 | 8193 | 12920 | 0.9000 | 0.0000 | |
| GSE63941 | DPF1 | 8193 | 206531_at | 0.8129 | 0.0002 | |
| GSE77861 | DPF1 | 8193 | 231599_x_at | 0.2171 | 0.2436 | |
| GSE97050 | DPF1 | 8193 | A_33_P3317277 | 0.3763 | 0.2151 | |
| SRP007169 | DPF1 | 8193 | RNAseq | 7.4036 | 0.0000 | |
| SRP133303 | DPF1 | 8193 | RNAseq | 2.9774 | 0.0000 | |
| SRP159526 | DPF1 | 8193 | RNAseq | 5.4250 | 0.0000 | |
| SRP219564 | DPF1 | 8193 | RNAseq | 2.2537 | 0.0009 | |
| TCGA | DPF1 | 8193 | RNAseq | 2.3872 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by DPF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPF1 | 8193 | 7 | 4 | 19 | |
| GSE20123 | DPF1 | 8193 | 7 | 3 | 20 | |
| GSE43470 | DPF1 | 8193 | 4 | 10 | 29 | |
| GSE46452 | DPF1 | 8193 | 47 | 2 | 10 | |
| GSE47630 | DPF1 | 8193 | 9 | 5 | 26 | |
| GSE54993 | DPF1 | 8193 | 17 | 3 | 50 | |
| GSE54994 | DPF1 | 8193 | 6 | 9 | 38 | |
| GSE60625 | DPF1 | 8193 | 9 | 0 | 2 | |
| GSE74703 | DPF1 | 8193 | 4 | 6 | 26 | |
| GSE74704 | DPF1 | 8193 | 7 | 1 | 12 | |
| TCGA | DPF1 | 8193 | 18 | 14 | 64 |
Total number of gains: 135; Total number of losses: 57; Total Number of normals: 296.
Somatic mutations of DPF1:
Generating mutation plots.
Highly correlated genes for DPF1:
Showing top 20/788 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPF1 | PCED1B | 0.793955 | 3 | 0 | 3 |
| DPF1 | LHB | 0.761835 | 3 | 0 | 3 |
| DPF1 | MS4A18 | 0.760545 | 3 | 0 | 3 |
| DPF1 | ALDH16A1 | 0.727277 | 3 | 0 | 3 |
| DPF1 | ADAMTS7 | 0.726936 | 3 | 0 | 3 |
| DPF1 | MEGF10 | 0.707493 | 3 | 0 | 3 |
| DPF1 | LRRC10 | 0.706482 | 3 | 0 | 3 |
| DPF1 | STRC | 0.702735 | 3 | 0 | 3 |
| DPF1 | SUN5 | 0.700708 | 4 | 0 | 4 |
| DPF1 | SLC39A5 | 0.699933 | 4 | 0 | 4 |
| DPF1 | OR2A5 | 0.699741 | 3 | 0 | 3 |
| DPF1 | GPR162 | 0.696652 | 3 | 0 | 3 |
| DPF1 | EMID1 | 0.694771 | 4 | 0 | 3 |
| DPF1 | ASPDH | 0.693953 | 4 | 0 | 4 |
| DPF1 | EFNA2 | 0.693492 | 3 | 0 | 3 |
| DPF1 | TMEM235 | 0.690877 | 4 | 0 | 4 |
| DPF1 | IFNL2 | 0.69047 | 3 | 0 | 3 |
| DPF1 | BEND3 | 0.685924 | 5 | 0 | 5 |
| DPF1 | IL9R | 0.683998 | 3 | 0 | 3 |
| DPF1 | NPW | 0.682511 | 4 | 0 | 3 |
For details and further investigation, click here
