| Full name: aspartate dehydrogenase domain containing | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 554235 | HGNC ID: HGNC:33856 | Ensembl Gene: ENSG00000204653 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASPDH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPDH | 554235 | 230912_at | 0.0472 | 0.8632 | |
| GSE26886 | ASPDH | 554235 | 230912_at | 0.3132 | 0.0079 | |
| GSE45670 | ASPDH | 554235 | 230912_at | -0.0078 | 0.9470 | |
| GSE53622 | ASPDH | 554235 | 9821 | 0.1143 | 0.2897 | |
| GSE53624 | ASPDH | 554235 | 9821 | 0.0862 | 0.2336 | |
| GSE63941 | ASPDH | 554235 | 230912_at | 0.5466 | 0.0037 | |
| GSE77861 | ASPDH | 554235 | 230912_at | -0.1409 | 0.1693 | |
| GSE97050 | ASPDH | 554235 | A_24_P690811 | -0.1046 | 0.7480 | |
| SRP133303 | ASPDH | 554235 | RNAseq | -0.4208 | 0.1580 | |
| SRP219564 | ASPDH | 554235 | RNAseq | -0.6234 | 0.1924 | |
| TCGA | ASPDH | 554235 | RNAseq | -2.8163 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ASPDH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPDH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPDH | 554235 | 3 | 4 | 23 | |
| GSE20123 | ASPDH | 554235 | 3 | 3 | 24 | |
| GSE43470 | ASPDH | 554235 | 4 | 11 | 28 | |
| GSE46452 | ASPDH | 554235 | 45 | 1 | 13 | |
| GSE47630 | ASPDH | 554235 | 10 | 6 | 24 | |
| GSE54993 | ASPDH | 554235 | 17 | 4 | 49 | |
| GSE54994 | ASPDH | 554235 | 4 | 14 | 35 | |
| GSE60625 | ASPDH | 554235 | 9 | 0 | 2 | |
| GSE74703 | ASPDH | 554235 | 4 | 7 | 25 | |
| GSE74704 | ASPDH | 554235 | 3 | 1 | 16 | |
| TCGA | ASPDH | 554235 | 14 | 19 | 63 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of ASPDH:
Generating mutation plots.
Highly correlated genes for ASPDH:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPDH | KAZALD1 | 0.758278 | 3 | 0 | 3 |
| ASPDH | FAM131A | 0.746221 | 3 | 0 | 3 |
| ASPDH | SYCE1L | 0.72591 | 3 | 0 | 3 |
| ASPDH | SIX3 | 0.719964 | 3 | 0 | 3 |
| ASPDH | RANBP3 | 0.719095 | 3 | 0 | 3 |
| ASPDH | HOXD9 | 0.706208 | 3 | 0 | 3 |
| ASPDH | STK32C | 0.69433 | 3 | 0 | 3 |
| ASPDH | DPF1 | 0.693953 | 4 | 0 | 4 |
| ASPDH | SLC22A1 | 0.691588 | 3 | 0 | 3 |
| ASPDH | GALK1 | 0.685448 | 3 | 0 | 3 |
| ASPDH | ZGLP1 | 0.684481 | 5 | 0 | 4 |
| ASPDH | HBE1 | 0.684211 | 3 | 0 | 3 |
| ASPDH | CDH23 | 0.683478 | 5 | 0 | 4 |
| ASPDH | PNMA6A | 0.682899 | 3 | 0 | 3 |
| ASPDH | PEX11G | 0.67788 | 4 | 0 | 4 |
| ASPDH | NPEPL1 | 0.676931 | 5 | 0 | 4 |
| ASPDH | IGFN1 | 0.67666 | 4 | 0 | 3 |
| ASPDH | LRRC71 | 0.675974 | 4 | 0 | 4 |
| ASPDH | KCNK9 | 0.674457 | 4 | 0 | 4 |
| ASPDH | WNT9A | 0.67436 | 3 | 0 | 3 |
For details and further investigation, click here
