PCED1B

 

Full name: PC-esterase domain containing 1B Alias Symbol: MGC16044
Type: protein-coding gene Cytoband: 12q13.11
Entrez ID: 91523 HGNC ID: HGNC:28255 Ensembl Gene: ENSG00000179715 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of PCED1B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PCED1B 91523 228298_at 0.3745 0.4368
GSE26886 PCED1B 91523 228298_at 1.1072 0.0004
GSE45670 PCED1B 91523 228298_at 0.2586 0.2868
GSE53622 PCED1B 91523 82966 0.7360 0.0000
GSE53624 PCED1B 91523 61626 0.7791 0.0000
GSE63941 PCED1B 91523 228298_at 0.7486 0.5427
GSE77861 PCED1B 91523 228298_at 0.1987 0.3074
SRP007169 PCED1B 91523 RNAseq 1.5876 0.0436
SRP064894 PCED1B 91523 RNAseq 0.8497 0.0005
SRP133303 PCED1B 91523 RNAseq 0.3877 0.1202
SRP159526 PCED1B 91523 RNAseq -0.8446 0.0722
SRP193095 PCED1B 91523 RNAseq 1.2112 0.0000
SRP219564 PCED1B 91523 RNAseq 0.7606 0.0863

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by PCED1B expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of PCED1B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PCED1B 91523 7 1 22
GSE20123 PCED1B 91523 7 1 22
GSE43470 PCED1B 91523 3 1 39
GSE46452 PCED1B 91523 8 1 50
GSE47630 PCED1B 91523 11 2 27
GSE54993 PCED1B 91523 0 5 65
GSE54994 PCED1B 91523 5 2 46
GSE60625 PCED1B 91523 0 0 11
GSE74703 PCED1B 91523 3 1 32
GSE74704 PCED1B 91523 3 1 16
TCGA PCED1B 91523 16 12 68

Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.  


 

Somatic mutations of PCED1B:

 

Generating mutation plots.

 

Highly correlated genes for PCED1B:

 

Showing top 20/409 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PCED1BDPF10.793955303
PCED1BC1QL10.735522303
PCED1BLILRB10.733973303
PCED1BSIPA1L30.733469303
PCED1BTEAD40.72994303
PCED1BIL2RB0.705819404
PCED1BZBTB320.698401404
PCED1BSPI10.684271505
PCED1BRNF2130.679636403
PCED1BRAC20.676026707
PCED1BSLC15A30.672612303
PCED1BTANGO20.669765404
PCED1BHSPG20.66955303
PCED1BHCK0.665612303
PCED1BIL21R0.66509403
PCED1BAPOC10.662349404
PCED1BA1BG0.659061303
PCED1BPSMB80.656905404
PCED1BPCOLCE0.654451404
PCED1BIKBIP0.649468404

For details and further investigation, click here