| Full name: dihydropyrimidinase like 3 | Alias Symbol: DRP-3|ULIP|CRMP4 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 1809 | HGNC ID: HGNC:3015 | Ensembl Gene: ENSG00000113657 | OMIM ID: 601168 |
| Drug and gene relationship at DGIdb | |||
Expression of DPYSL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPYSL3 | 1809 | 201431_s_at | -1.0251 | 0.4404 | |
| GSE20347 | DPYSL3 | 1809 | 201431_s_at | 0.7606 | 0.0890 | |
| GSE23400 | DPYSL3 | 1809 | 201431_s_at | 0.3397 | 0.1218 | |
| GSE26886 | DPYSL3 | 1809 | 201431_s_at | 2.7594 | 0.0000 | |
| GSE29001 | DPYSL3 | 1809 | 201431_s_at | 1.0083 | 0.0497 | |
| GSE38129 | DPYSL3 | 1809 | 201431_s_at | 0.2376 | 0.6692 | |
| GSE45670 | DPYSL3 | 1809 | 201431_s_at | -1.5218 | 0.0008 | |
| GSE53622 | DPYSL3 | 1809 | 7685 | -0.3572 | 0.0017 | |
| GSE53624 | DPYSL3 | 1809 | 7685 | -0.0244 | 0.8049 | |
| GSE63941 | DPYSL3 | 1809 | 201431_s_at | -2.4048 | 0.0355 | |
| GSE77861 | DPYSL3 | 1809 | 201431_s_at | 2.5676 | 0.0032 | |
| GSE97050 | DPYSL3 | 1809 | A_24_P149036 | -0.5571 | 0.1774 | |
| SRP007169 | DPYSL3 | 1809 | RNAseq | 3.5346 | 0.0000 | |
| SRP008496 | DPYSL3 | 1809 | RNAseq | 4.2725 | 0.0000 | |
| SRP064894 | DPYSL3 | 1809 | RNAseq | 0.9489 | 0.0120 | |
| SRP133303 | DPYSL3 | 1809 | RNAseq | 0.5272 | 0.1823 | |
| SRP159526 | DPYSL3 | 1809 | RNAseq | 0.6868 | 0.2414 | |
| SRP193095 | DPYSL3 | 1809 | RNAseq | 2.0206 | 0.0000 | |
| SRP219564 | DPYSL3 | 1809 | RNAseq | 0.0773 | 0.9406 | |
| TCGA | DPYSL3 | 1809 | RNAseq | -0.0948 | 0.4551 |
Upregulated datasets: 6; Downregulated datasets: 2.
Survival by DPYSL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPYSL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPYSL3 | 1809 | 1 | 12 | 17 | |
| GSE20123 | DPYSL3 | 1809 | 1 | 12 | 17 | |
| GSE43470 | DPYSL3 | 1809 | 2 | 9 | 32 | |
| GSE46452 | DPYSL3 | 1809 | 0 | 27 | 32 | |
| GSE47630 | DPYSL3 | 1809 | 0 | 20 | 20 | |
| GSE54993 | DPYSL3 | 1809 | 9 | 1 | 60 | |
| GSE54994 | DPYSL3 | 1809 | 2 | 15 | 36 | |
| GSE60625 | DPYSL3 | 1809 | 0 | 0 | 11 | |
| GSE74703 | DPYSL3 | 1809 | 2 | 7 | 27 | |
| GSE74704 | DPYSL3 | 1809 | 1 | 7 | 12 | |
| TCGA | DPYSL3 | 1809 | 3 | 40 | 53 |
Total number of gains: 21; Total number of losses: 150; Total Number of normals: 317.
Somatic mutations of DPYSL3:
Generating mutation plots.
Highly correlated genes for DPYSL3:
Showing top 20/1176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPYSL3 | SLC35F1 | 0.767653 | 3 | 0 | 3 |
| DPYSL3 | MYADM | 0.749574 | 5 | 0 | 4 |
| DPYSL3 | CYS1 | 0.740915 | 6 | 0 | 6 |
| DPYSL3 | ITGA7 | 0.734303 | 6 | 0 | 6 |
| DPYSL3 | KATNAL1 | 0.731005 | 6 | 0 | 6 |
| DPYSL3 | PLBD2 | 0.730232 | 3 | 0 | 3 |
| DPYSL3 | MEOX2 | 0.729197 | 6 | 0 | 6 |
| DPYSL3 | MSRB3 | 0.727328 | 7 | 0 | 6 |
| DPYSL3 | IRS2 | 0.726133 | 7 | 0 | 5 |
| DPYSL3 | FERMT2 | 0.725818 | 13 | 0 | 12 |
| DPYSL3 | WDR81 | 0.723136 | 3 | 0 | 3 |
| DPYSL3 | AKT3 | 0.719146 | 10 | 0 | 10 |
| DPYSL3 | LRRTM1 | 0.718585 | 3 | 0 | 3 |
| DPYSL3 | ALPK3 | 0.7179 | 4 | 0 | 4 |
| DPYSL3 | SLC41A1 | 0.716008 | 3 | 0 | 3 |
| DPYSL3 | TMED8 | 0.714005 | 3 | 0 | 3 |
| DPYSL3 | C11orf96 | 0.709629 | 5 | 0 | 5 |
| DPYSL3 | TGFB1I1 | 0.709473 | 12 | 0 | 10 |
| DPYSL3 | TP53I13 | 0.707268 | 3 | 0 | 3 |
| DPYSL3 | EPM2A | 0.705863 | 5 | 0 | 5 |
For details and further investigation, click here
