| Full name: katanin catalytic subunit A1 like 1 | Alias Symbol: MGC2599 | ||
| Type: protein-coding gene | Cytoband: 13q12.3 | ||
| Entrez ID: 84056 | HGNC ID: HGNC:28361 | Ensembl Gene: ENSG00000102781 | OMIM ID: 614764 |
| Drug and gene relationship at DGIdb | |||
Expression of KATNAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KATNAL1 | 84056 | 227713_at | -0.4001 | 0.6359 | |
| GSE26886 | KATNAL1 | 84056 | 227713_at | 1.0635 | 0.0000 | |
| GSE45670 | KATNAL1 | 84056 | 227713_at | -0.6468 | 0.0109 | |
| GSE53622 | KATNAL1 | 84056 | 84631 | -0.3334 | 0.0098 | |
| GSE53624 | KATNAL1 | 84056 | 84631 | 0.1959 | 0.0231 | |
| GSE63941 | KATNAL1 | 84056 | 227713_at | -1.8458 | 0.0238 | |
| GSE77861 | KATNAL1 | 84056 | 227713_at | 0.3402 | 0.4450 | |
| GSE97050 | KATNAL1 | 84056 | A_32_P75284 | -0.6508 | 0.1782 | |
| SRP007169 | KATNAL1 | 84056 | RNAseq | 1.5707 | 0.0040 | |
| SRP008496 | KATNAL1 | 84056 | RNAseq | 1.3747 | 0.0003 | |
| SRP064894 | KATNAL1 | 84056 | RNAseq | 0.6015 | 0.0013 | |
| SRP133303 | KATNAL1 | 84056 | RNAseq | 0.4218 | 0.0342 | |
| SRP159526 | KATNAL1 | 84056 | RNAseq | -0.0278 | 0.9277 | |
| SRP193095 | KATNAL1 | 84056 | RNAseq | 0.7915 | 0.0000 | |
| SRP219564 | KATNAL1 | 84056 | RNAseq | -0.4388 | 0.4256 | |
| TCGA | KATNAL1 | 84056 | RNAseq | 0.0749 | 0.4452 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by KATNAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KATNAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KATNAL1 | 84056 | 1 | 13 | 16 | |
| GSE20123 | KATNAL1 | 84056 | 1 | 12 | 17 | |
| GSE43470 | KATNAL1 | 84056 | 2 | 12 | 29 | |
| GSE46452 | KATNAL1 | 84056 | 0 | 33 | 26 | |
| GSE47630 | KATNAL1 | 84056 | 2 | 27 | 11 | |
| GSE54993 | KATNAL1 | 84056 | 12 | 2 | 56 | |
| GSE54994 | KATNAL1 | 84056 | 2 | 14 | 37 | |
| GSE60625 | KATNAL1 | 84056 | 0 | 3 | 8 | |
| GSE74703 | KATNAL1 | 84056 | 2 | 9 | 25 | |
| GSE74704 | KATNAL1 | 84056 | 0 | 10 | 10 | |
| TCGA | KATNAL1 | 84056 | 8 | 37 | 51 |
Total number of gains: 30; Total number of losses: 172; Total Number of normals: 286.
Somatic mutations of KATNAL1:
Generating mutation plots.
Highly correlated genes for KATNAL1:
Showing top 20/886 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KATNAL1 | GIPC3 | 0.79206 | 3 | 0 | 3 |
| KATNAL1 | PURA | 0.783056 | 3 | 0 | 3 |
| KATNAL1 | PRKG2 | 0.780346 | 3 | 0 | 3 |
| KATNAL1 | PLA2G5 | 0.776168 | 3 | 0 | 3 |
| KATNAL1 | PDZD4 | 0.77328 | 3 | 0 | 3 |
| KATNAL1 | STK33 | 0.761896 | 3 | 0 | 3 |
| KATNAL1 | SGCA | 0.761623 | 4 | 0 | 4 |
| KATNAL1 | MAP4 | 0.74646 | 3 | 0 | 3 |
| KATNAL1 | KIF5C | 0.741553 | 4 | 0 | 4 |
| KATNAL1 | STARD9 | 0.741366 | 5 | 0 | 5 |
| KATNAL1 | SYNC | 0.736381 | 4 | 0 | 4 |
| KATNAL1 | DPYSL3 | 0.731005 | 6 | 0 | 6 |
| KATNAL1 | ACTN2 | 0.728811 | 3 | 0 | 3 |
| KATNAL1 | IQUB | 0.725617 | 4 | 0 | 3 |
| KATNAL1 | LRRTM1 | 0.725368 | 3 | 0 | 3 |
| KATNAL1 | APBB1 | 0.722285 | 4 | 0 | 4 |
| KATNAL1 | CADM2 | 0.717465 | 3 | 0 | 3 |
| KATNAL1 | RBM24 | 0.715435 | 6 | 0 | 5 |
| KATNAL1 | TNIK | 0.715242 | 4 | 0 | 4 |
| KATNAL1 | ZNF385D | 0.715185 | 4 | 0 | 3 |
For details and further investigation, click here
