LRRTM1

 

Full name: leucine rich repeat transmembrane neuronal 1 Alias Symbol: FLJ32082
Type: protein-coding gene Cytoband: 2p12
Entrez ID: 347730 HGNC ID: HGNC:19408 Ensembl Gene: ENSG00000162951 OMIM ID: 610867
Drug and gene relationship at DGIdb

 

Expression of LRRTM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRTM1 347730 238815_at -0.1368 0.7976
GSE26886 LRRTM1 347730 238815_at 0.1118 0.3514
GSE45670 LRRTM1 347730 238815_at 0.0626 0.5299
GSE53622 LRRTM1 347730 146412 -1.2128 0.0000
GSE53624 LRRTM1 347730 146412 -1.7091 0.0000
GSE63941 LRRTM1 347730 238815_at 0.1366 0.3917
GSE77861 LRRTM1 347730 238815_at 0.0479 0.6537
GSE97050 LRRTM1 347730 A_23_P131330 -1.1430 0.1585
TCGA LRRTM1 347730 RNAseq -1.5754 0.0865

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by LRRTM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of LRRTM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRTM1 347730 9 2 19
GSE20123 LRRTM1 347730 8 2 20
GSE43470 LRRTM1 347730 5 0 38
GSE46452 LRRTM1 347730 2 3 54
GSE47630 LRRTM1 347730 7 0 33
GSE54993 LRRTM1 347730 0 6 64
GSE54994 LRRTM1 347730 10 0 43
GSE60625 LRRTM1 347730 0 3 8
GSE74703 LRRTM1 347730 5 0 31
GSE74704 LRRTM1 347730 5 1 14
TCGA LRRTM1 347730 33 3 60

Total number of gains: 84; Total number of losses: 20; Total Number of normals: 384.  


 

Somatic mutations of LRRTM1:

 

Generating mutation plots.

 

Highly correlated genes for LRRTM1:

 

Showing top 20/395 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRTM1PYGM0.78717404
LRRTM1FRRS1L0.777554303
LRRTM1FAM107A0.774407303
LRRTM1SCN7A0.769264404
LRRTM1RASD20.759123303
LRRTM1KCNMB10.749696404
LRRTM1SORCS10.749179404
LRRTM1KCNJ90.746517303
LRRTM1SH3BGR0.745603404
LRRTM1RBFOX30.743572303
LRRTM1KBTBD120.742018505
LRRTM1PGR0.737535404
LRRTM1NPY0.733504303
LRRTM1TCEAL20.730643404
LRRTM1AQP10.72569404
LRRTM1KATNAL10.725368303
LRRTM1RBPMS20.725329404
LRRTM1PLP10.724402404
LRRTM1SLITRK30.721816303
LRRTM1ADCY50.721045505

For details and further investigation, click here