| Full name: Down syndrome critical region 10 | Alias Symbol: | ||
| Type: non-coding RNA | Cytoband: 21q22.13 | ||
| Entrez ID: 259234 | HGNC ID: HGNC:16302 | Ensembl Gene: ENSG00000233316 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DSCR10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DSCR10 | 259234 | 1552467_at | -0.1009 | 0.6867 | |
| GSE26886 | DSCR10 | 259234 | 1552467_at | -0.2952 | 0.0351 | |
| GSE45670 | DSCR10 | 259234 | 1552467_at | 0.0716 | 0.4771 | |
| GSE53622 | DSCR10 | 259234 | 71561 | 0.1528 | 0.1269 | |
| GSE53624 | DSCR10 | 259234 | 71561 | 0.2163 | 0.1272 | |
| GSE63941 | DSCR10 | 259234 | 1552467_at | 0.2867 | 0.0339 | |
| GSE77861 | DSCR10 | 259234 | 1552467_at | -0.0662 | 0.5734 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DSCR10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DSCR10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DSCR10 | 259234 | 2 | 9 | 19 | |
| GSE20123 | DSCR10 | 259234 | 2 | 10 | 18 | |
| GSE43470 | DSCR10 | 259234 | 1 | 11 | 31 | |
| GSE46452 | DSCR10 | 259234 | 1 | 21 | 37 | |
| GSE47630 | DSCR10 | 259234 | 6 | 17 | 17 | |
| GSE54993 | DSCR10 | 259234 | 8 | 1 | 61 | |
| GSE54994 | DSCR10 | 259234 | 3 | 9 | 41 | |
| GSE60625 | DSCR10 | 259234 | 0 | 0 | 11 | |
| GSE74703 | DSCR10 | 259234 | 1 | 8 | 27 | |
| GSE74704 | DSCR10 | 259234 | 1 | 7 | 12 | |
| TCGA | DSCR10 | 259234 | 8 | 41 | 47 |
Total number of gains: 33; Total number of losses: 134; Total Number of normals: 321.
Somatic mutations of DSCR10:
Generating mutation plots.
Highly correlated genes for DSCR10:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DSCR10 | NUTM1 | 0.7725 | 4 | 0 | 4 |
| DSCR10 | TMEM105 | 0.752396 | 5 | 0 | 5 |
| DSCR10 | UNC5A | 0.743263 | 3 | 0 | 3 |
| DSCR10 | TSPAN11 | 0.726181 | 3 | 0 | 3 |
| DSCR10 | TRPM8 | 0.705137 | 4 | 0 | 4 |
| DSCR10 | PRR7-AS1 | 0.70423 | 3 | 0 | 3 |
| DSCR10 | TTC12 | 0.702955 | 4 | 0 | 4 |
| DSCR10 | SYCN | 0.700296 | 3 | 0 | 3 |
| DSCR10 | PRSS33 | 0.69977 | 3 | 0 | 3 |
| DSCR10 | TTTY5 | 0.699147 | 5 | 0 | 5 |
| DSCR10 | VWA5B1 | 0.699074 | 3 | 0 | 3 |
| DSCR10 | MAPK12 | 0.698939 | 3 | 0 | 3 |
| DSCR10 | GJD4 | 0.688303 | 4 | 0 | 3 |
| DSCR10 | CYP2B6 | 0.68271 | 3 | 0 | 3 |
| DSCR10 | SIRPB1 | 0.680587 | 4 | 0 | 3 |
| DSCR10 | CLDN9 | 0.679855 | 4 | 0 | 3 |
| DSCR10 | MYL7 | 0.676948 | 3 | 0 | 3 |
| DSCR10 | XAGE2 | 0.674673 | 3 | 0 | 3 |
| DSCR10 | CIB3 | 0.672516 | 5 | 0 | 4 |
| DSCR10 | TMPO-AS1 | 0.669043 | 3 | 0 | 3 |
For details and further investigation, click here
