| Full name: caspase recruitment domain family member 14 | Alias Symbol: CARMA2|BIMP2 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 79092 | HGNC ID: HGNC:16446 | Ensembl Gene: ENSG00000141527 | OMIM ID: 607211 |
| Drug and gene relationship at DGIdb | |||
Expression of CARD14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CARD14 | 79092 | 232608_x_at | -0.2598 | 0.7727 | |
| GSE20347 | CARD14 | 79092 | 220599_s_at | -0.6328 | 0.0000 | |
| GSE23400 | CARD14 | 79092 | 220599_s_at | -0.5014 | 0.0000 | |
| GSE26886 | CARD14 | 79092 | 232608_x_at | -1.1203 | 0.0002 | |
| GSE29001 | CARD14 | 79092 | 220599_s_at | -0.7439 | 0.0021 | |
| GSE38129 | CARD14 | 79092 | 220599_s_at | -0.5068 | 0.0279 | |
| GSE45670 | CARD14 | 79092 | 232608_x_at | -0.0836 | 0.7441 | |
| GSE53622 | CARD14 | 79092 | 82330 | -0.8011 | 0.0000 | |
| GSE53624 | CARD14 | 79092 | 82330 | -1.4418 | 0.0000 | |
| GSE63941 | CARD14 | 79092 | 224113_at | 0.2363 | 0.1886 | |
| GSE77861 | CARD14 | 79092 | 224113_at | -0.0929 | 0.5304 | |
| GSE97050 | CARD14 | 79092 | A_33_P3228315 | 0.0051 | 0.9849 | |
| SRP007169 | CARD14 | 79092 | RNAseq | -2.2716 | 0.0000 | |
| SRP008496 | CARD14 | 79092 | RNAseq | -2.2642 | 0.0000 | |
| SRP064894 | CARD14 | 79092 | RNAseq | -0.9725 | 0.0047 | |
| SRP133303 | CARD14 | 79092 | RNAseq | -1.2937 | 0.0000 | |
| SRP159526 | CARD14 | 79092 | RNAseq | -1.5657 | 0.0011 | |
| SRP193095 | CARD14 | 79092 | RNAseq | -0.4970 | 0.0893 | |
| SRP219564 | CARD14 | 79092 | RNAseq | -1.4972 | 0.0680 | |
| TCGA | CARD14 | 79092 | RNAseq | 0.8823 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CARD14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CARD14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CARD14 | 79092 | 4 | 3 | 23 | |
| GSE20123 | CARD14 | 79092 | 4 | 3 | 23 | |
| GSE43470 | CARD14 | 79092 | 3 | 5 | 35 | |
| GSE46452 | CARD14 | 79092 | 34 | 0 | 25 | |
| GSE47630 | CARD14 | 79092 | 9 | 1 | 30 | |
| GSE54993 | CARD14 | 79092 | 2 | 5 | 63 | |
| GSE54994 | CARD14 | 79092 | 10 | 6 | 37 | |
| GSE60625 | CARD14 | 79092 | 6 | 0 | 5 | |
| GSE74703 | CARD14 | 79092 | 3 | 3 | 30 | |
| GSE74704 | CARD14 | 79092 | 4 | 3 | 13 | |
| TCGA | CARD14 | 79092 | 28 | 10 | 58 |
Total number of gains: 107; Total number of losses: 39; Total Number of normals: 342.
Somatic mutations of CARD14:
Generating mutation plots.
Highly correlated genes for CARD14:
Showing top 20/632 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CARD14 | EVPL | 0.782499 | 9 | 0 | 9 |
| CARD14 | EPS8L1 | 0.751045 | 9 | 0 | 9 |
| CARD14 | GRHL3 | 0.749378 | 5 | 0 | 5 |
| CARD14 | DUSP15 | 0.73654 | 3 | 0 | 3 |
| CARD14 | IL22RA1 | 0.734492 | 7 | 0 | 7 |
| CARD14 | CLEC18C | 0.733947 | 3 | 0 | 3 |
| CARD14 | GDPD3 | 0.73344 | 9 | 0 | 9 |
| CARD14 | TMEM154 | 0.725314 | 5 | 0 | 5 |
| CARD14 | C15orf48 | 0.723206 | 5 | 0 | 4 |
| CARD14 | TTC22 | 0.721642 | 10 | 0 | 10 |
| CARD14 | SULT2B1 | 0.719479 | 7 | 0 | 7 |
| CARD14 | PRDM1 | 0.71487 | 9 | 0 | 9 |
| CARD14 | GIPC1 | 0.714579 | 9 | 0 | 9 |
| CARD14 | SCNN1B | 0.713368 | 9 | 0 | 9 |
| CARD14 | TMEM40 | 0.713189 | 10 | 0 | 9 |
| CARD14 | CEACAM7 | 0.710793 | 9 | 0 | 8 |
| CARD14 | RDH13 | 0.710749 | 6 | 0 | 6 |
| CARD14 | MALL | 0.709898 | 9 | 0 | 9 |
| CARD14 | ATP10B | 0.708637 | 10 | 0 | 9 |
| CARD14 | RAB10 | 0.70826 | 5 | 0 | 5 |
For details and further investigation, click here
