| Full name: dual specificity phosphatase 23 | Alias Symbol: FLJ20442|DUSP25 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 54935 | HGNC ID: HGNC:21480 | Ensembl Gene: ENSG00000158716 | OMIM ID: 618361 |
| Drug and gene relationship at DGIdb | |||
Expression of DUSP23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUSP23 | 54935 | 223402_at | 0.4095 | 0.2725 | |
| GSE26886 | DUSP23 | 54935 | 223402_at | 0.6080 | 0.0354 | |
| GSE45670 | DUSP23 | 54935 | 223402_at | 0.0361 | 0.7555 | |
| GSE53622 | DUSP23 | 54935 | 33677 | -0.2338 | 0.0065 | |
| GSE53624 | DUSP23 | 54935 | 33677 | -0.0456 | 0.4655 | |
| GSE63941 | DUSP23 | 54935 | 223402_at | -0.0136 | 0.9896 | |
| GSE77861 | DUSP23 | 54935 | 223402_at | -0.2363 | 0.6645 | |
| GSE97050 | DUSP23 | 54935 | A_33_P3272698 | 0.3603 | 0.3286 | |
| SRP007169 | DUSP23 | 54935 | RNAseq | -1.4379 | 0.0053 | |
| SRP008496 | DUSP23 | 54935 | RNAseq | -0.6342 | 0.0754 | |
| SRP064894 | DUSP23 | 54935 | RNAseq | 0.5272 | 0.1601 | |
| SRP133303 | DUSP23 | 54935 | RNAseq | -0.1093 | 0.5818 | |
| SRP159526 | DUSP23 | 54935 | RNAseq | -0.0312 | 0.8546 | |
| SRP193095 | DUSP23 | 54935 | RNAseq | -0.2259 | 0.2091 | |
| SRP219564 | DUSP23 | 54935 | RNAseq | 0.5122 | 0.3220 | |
| TCGA | DUSP23 | 54935 | RNAseq | 0.2451 | 0.0327 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DUSP23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUSP23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUSP23 | 54935 | 10 | 0 | 20 | |
| GSE20123 | DUSP23 | 54935 | 10 | 0 | 20 | |
| GSE43470 | DUSP23 | 54935 | 7 | 2 | 34 | |
| GSE46452 | DUSP23 | 54935 | 2 | 1 | 56 | |
| GSE47630 | DUSP23 | 54935 | 14 | 0 | 26 | |
| GSE54993 | DUSP23 | 54935 | 0 | 5 | 65 | |
| GSE54994 | DUSP23 | 54935 | 16 | 0 | 37 | |
| GSE60625 | DUSP23 | 54935 | 0 | 0 | 11 | |
| GSE74703 | DUSP23 | 54935 | 7 | 2 | 27 | |
| GSE74704 | DUSP23 | 54935 | 4 | 0 | 16 | |
| TCGA | DUSP23 | 54935 | 43 | 3 | 50 |
Total number of gains: 113; Total number of losses: 13; Total Number of normals: 362.
Somatic mutations of DUSP23:
Generating mutation plots.
Highly correlated genes for DUSP23:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUSP23 | TOMM40L | 0.806668 | 3 | 0 | 3 |
| DUSP23 | CPLX1 | 0.802665 | 3 | 0 | 3 |
| DUSP23 | TARBP1 | 0.800808 | 3 | 0 | 3 |
| DUSP23 | RPP40 | 0.799136 | 3 | 0 | 3 |
| DUSP23 | VGLL4 | 0.788901 | 3 | 0 | 3 |
| DUSP23 | NVL | 0.775935 | 3 | 0 | 3 |
| DUSP23 | PTPN4 | 0.773672 | 3 | 0 | 3 |
| DUSP23 | FASN | 0.770848 | 3 | 0 | 3 |
| DUSP23 | DENND4B | 0.767973 | 3 | 0 | 3 |
| DUSP23 | RP9 | 0.764231 | 3 | 0 | 3 |
| DUSP23 | KRTCAP2 | 0.763909 | 3 | 0 | 3 |
| DUSP23 | EED | 0.763391 | 3 | 0 | 3 |
| DUSP23 | GSDMB | 0.763011 | 3 | 0 | 3 |
| DUSP23 | RPL7L1 | 0.762781 | 3 | 0 | 3 |
| DUSP23 | NAT10 | 0.75792 | 3 | 0 | 3 |
| DUSP23 | CBFA2T2 | 0.746592 | 3 | 0 | 3 |
| DUSP23 | RAB15 | 0.74399 | 3 | 0 | 3 |
| DUSP23 | GORASP2 | 0.742951 | 3 | 0 | 3 |
| DUSP23 | ZNF107 | 0.742375 | 3 | 0 | 3 |
| DUSP23 | EVL | 0.739148 | 3 | 0 | 3 |
For details and further investigation, click here
