DUSP26

 

Full name: dual specificity phosphatase 26 Alias Symbol: MGC1136|DUSP24
Type: protein-coding gene Cytoband: 8p12
Entrez ID: 78986 HGNC ID: HGNC:28161 Ensembl Gene: ENSG00000133878 OMIM ID: 618368
Drug and gene relationship at DGIdb

 

Expression of DUSP26:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DUSP26 78986 219144_at -0.2017 0.3648
GSE20347 DUSP26 78986 219144_at -0.0383 0.6772
GSE23400 DUSP26 78986 219144_at -0.1421 0.0003
GSE26886 DUSP26 78986 219144_at 0.0400 0.8068
GSE29001 DUSP26 78986 219144_at -0.1184 0.5260
GSE38129 DUSP26 78986 219144_at -0.2059 0.0194
GSE45670 DUSP26 78986 219144_at -0.1532 0.0491
GSE53622 DUSP26 78986 2178 -0.4000 0.0003
GSE53624 DUSP26 78986 2178 -0.6448 0.0000
GSE63941 DUSP26 78986 219144_at -0.0932 0.5516
GSE77861 DUSP26 78986 219144_at -0.0086 0.9459
GSE97050 DUSP26 78986 A_23_P146134 -0.7681 0.1482
SRP133303 DUSP26 78986 RNAseq -0.9319 0.1054
SRP159526 DUSP26 78986 RNAseq 0.4345 0.4616
TCGA DUSP26 78986 RNAseq -2.1308 0.0001

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by DUSP26 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DUSP26:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DUSP26 78986 4 10 16
GSE20123 DUSP26 78986 4 10 16
GSE43470 DUSP26 78986 4 7 32
GSE46452 DUSP26 78986 16 10 33
GSE47630 DUSP26 78986 11 7 22
GSE54993 DUSP26 78986 2 16 52
GSE54994 DUSP26 78986 11 16 26
GSE60625 DUSP26 78986 3 0 8
GSE74703 DUSP26 78986 4 6 26
GSE74704 DUSP26 78986 3 6 11
TCGA DUSP26 78986 24 33 39

Total number of gains: 86; Total number of losses: 121; Total Number of normals: 281.  


 

Somatic mutations of DUSP26:

 

Generating mutation plots.

 

Highly correlated genes for DUSP26:

 

Showing top 20/563 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DUSP26MAG0.676418303
DUSP26APOB0.66156505
DUSP26KBTBD120.658272404
DUSP26PSG70.655427403
DUSP26PLXNB30.651009303
DUSP26WAS0.647932403
DUSP26MUC130.64696403
DUSP26PRDM110.644585404
DUSP26SYT20.644168505
DUSP26TMEM8B0.642897505
DUSP26SERPINA50.640841504
DUSP26RNF185-AS10.63737404
DUSP26DNAJA40.636917403
DUSP26PTPRT0.635198403
DUSP26CSDC20.635024705
DUSP26DUSP210.633429403
DUSP26G6PC20.632311503
DUSP26TMPRSS50.628734403
DUSP26FOXN3-AS20.627415403
DUSP26LYZL60.624603303

For details and further investigation, click here