| Full name: PR/SET domain 11 | Alias Symbol: PFM8 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 56981 | HGNC ID: HGNC:13996 | Ensembl Gene: ENSG00000019485 | OMIM ID: 616347 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM11 | 56981 | 229687_s_at | -0.1691 | 0.8543 | |
| GSE20347 | PRDM11 | 56981 | 220571_at | -0.0438 | 0.6044 | |
| GSE23400 | PRDM11 | 56981 | 220571_at | -0.2139 | 0.0000 | |
| GSE26886 | PRDM11 | 56981 | 220571_at | 0.1869 | 0.1707 | |
| GSE29001 | PRDM11 | 56981 | 220571_at | -0.1605 | 0.3080 | |
| GSE38129 | PRDM11 | 56981 | 220571_at | -0.1498 | 0.0819 | |
| GSE45670 | PRDM11 | 56981 | 220571_at | 0.1273 | 0.1826 | |
| GSE53622 | PRDM11 | 56981 | 85114 | 0.0010 | 0.9927 | |
| GSE53624 | PRDM11 | 56981 | 85114 | 0.1603 | 0.0066 | |
| GSE63941 | PRDM11 | 56981 | 229687_s_at | 0.5340 | 0.3902 | |
| GSE77861 | PRDM11 | 56981 | 220571_at | -0.1410 | 0.0714 | |
| GSE97050 | PRDM11 | 56981 | A_24_P9833 | -0.0734 | 0.8496 | |
| SRP007169 | PRDM11 | 56981 | RNAseq | 1.5977 | 0.0081 | |
| SRP064894 | PRDM11 | 56981 | RNAseq | 0.1422 | 0.6268 | |
| SRP133303 | PRDM11 | 56981 | RNAseq | 0.6900 | 0.0515 | |
| SRP159526 | PRDM11 | 56981 | RNAseq | 0.5166 | 0.0683 | |
| SRP193095 | PRDM11 | 56981 | RNAseq | 0.8631 | 0.0000 | |
| SRP219564 | PRDM11 | 56981 | RNAseq | -0.2728 | 0.3853 | |
| TCGA | PRDM11 | 56981 | RNAseq | -0.0833 | 0.4792 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRDM11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM11 | 56981 | 1 | 8 | 21 | |
| GSE20123 | PRDM11 | 56981 | 1 | 7 | 22 | |
| GSE43470 | PRDM11 | 56981 | 2 | 4 | 37 | |
| GSE46452 | PRDM11 | 56981 | 8 | 5 | 46 | |
| GSE47630 | PRDM11 | 56981 | 3 | 9 | 28 | |
| GSE54993 | PRDM11 | 56981 | 3 | 0 | 67 | |
| GSE54994 | PRDM11 | 56981 | 4 | 9 | 40 | |
| GSE60625 | PRDM11 | 56981 | 0 | 0 | 11 | |
| GSE74703 | PRDM11 | 56981 | 2 | 2 | 32 | |
| GSE74704 | PRDM11 | 56981 | 1 | 6 | 13 | |
| TCGA | PRDM11 | 56981 | 15 | 19 | 62 |
Total number of gains: 40; Total number of losses: 69; Total Number of normals: 379.
Somatic mutations of PRDM11:
Generating mutation plots.
Highly correlated genes for PRDM11:
Showing top 20/656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM11 | MSH4 | 0.729364 | 3 | 0 | 3 |
| PRDM11 | LMAN1L | 0.725316 | 5 | 0 | 5 |
| PRDM11 | PHF7 | 0.718993 | 5 | 0 | 5 |
| PRDM11 | KRTAP5-8 | 0.718939 | 5 | 0 | 5 |
| PRDM11 | KLF15 | 0.706694 | 4 | 0 | 4 |
| PRDM11 | NAT2 | 0.692344 | 3 | 0 | 3 |
| PRDM11 | STXBP6 | 0.691442 | 3 | 0 | 3 |
| PRDM11 | SCNN1G | 0.68508 | 5 | 0 | 5 |
| PRDM11 | AKAP5 | 0.682592 | 4 | 0 | 4 |
| PRDM11 | TTR | 0.680663 | 4 | 0 | 4 |
| PRDM11 | SYT13 | 0.680235 | 3 | 0 | 3 |
| PRDM11 | GK2 | 0.679454 | 4 | 0 | 4 |
| PRDM11 | TAS2R3 | 0.67906 | 5 | 0 | 5 |
| PRDM11 | CDKL5 | 0.677629 | 4 | 0 | 4 |
| PRDM11 | GRIN2A | 0.67721 | 5 | 0 | 5 |
| PRDM11 | CAPN11 | 0.675847 | 4 | 0 | 3 |
| PRDM11 | IFNA17 | 0.675229 | 4 | 0 | 4 |
| PRDM11 | TOM1L2 | 0.671521 | 5 | 0 | 5 |
| PRDM11 | GABRA6 | 0.665183 | 4 | 0 | 3 |
| PRDM11 | SSTR4 | 0.664868 | 7 | 0 | 6 |
For details and further investigation, click here
