| Full name: decapping exoribonuclease | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 1797 | HGNC ID: HGNC:2992 | Ensembl Gene: ENSG00000204348 | OMIM ID: 605996 |
| Drug and gene relationship at DGIdb | |||
Expression of DXO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DXO | 1797 | 38157_at | 0.1948 | 0.7672 | |
| GSE20347 | DXO | 1797 | 38157_at | -0.0613 | 0.5346 | |
| GSE23400 | DXO | 1797 | 38157_at | -0.0624 | 0.0794 | |
| GSE26886 | DXO | 1797 | 38157_at | 0.2343 | 0.1695 | |
| GSE29001 | DXO | 1797 | 38157_at | -0.1343 | 0.5645 | |
| GSE38129 | DXO | 1797 | 38157_at | 0.0268 | 0.8224 | |
| GSE45670 | DXO | 1797 | 38157_at | -0.1180 | 0.2437 | |
| GSE53622 | DXO | 1797 | 80627 | 0.3175 | 0.0000 | |
| GSE53624 | DXO | 1797 | 80627 | 0.4557 | 0.0000 | |
| GSE63941 | DXO | 1797 | 38157_at | -0.1544 | 0.6062 | |
| GSE77861 | DXO | 1797 | 38157_at | -0.2053 | 0.0972 | |
| SRP007169 | DXO | 1797 | RNAseq | 0.1348 | 0.7871 | |
| SRP008496 | DXO | 1797 | RNAseq | 0.0748 | 0.8339 | |
| SRP064894 | DXO | 1797 | RNAseq | 0.3642 | 0.0421 | |
| SRP133303 | DXO | 1797 | RNAseq | -0.0503 | 0.7458 | |
| SRP159526 | DXO | 1797 | RNAseq | 0.5206 | 0.1486 | |
| SRP193095 | DXO | 1797 | RNAseq | 0.1573 | 0.0868 | |
| SRP219564 | DXO | 1797 | RNAseq | 0.1692 | 0.5233 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DXO expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DXO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DXO | 1797 | 5 | 1 | 24 | |
| GSE20123 | DXO | 1797 | 5 | 1 | 24 | |
| GSE43470 | DXO | 1797 | 5 | 1 | 37 | |
| GSE46452 | DXO | 1797 | 1 | 10 | 48 | |
| GSE47630 | DXO | 1797 | 7 | 4 | 29 | |
| GSE54993 | DXO | 1797 | 2 | 1 | 67 | |
| GSE54994 | DXO | 1797 | 11 | 4 | 38 | |
| GSE60625 | DXO | 1797 | 0 | 1 | 10 | |
| GSE74703 | DXO | 1797 | 5 | 0 | 31 | |
| GSE74704 | DXO | 1797 | 2 | 0 | 18 |
Total number of gains: 43; Total number of losses: 23; Total Number of normals: 326.
Somatic mutations of DXO:
Generating mutation plots.
Highly correlated genes for DXO:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DXO | CACNB3 | 0.740759 | 3 | 0 | 3 |
| DXO | PRRC2A | 0.683111 | 4 | 0 | 4 |
| DXO | KLC4 | 0.655567 | 3 | 0 | 3 |
| DXO | LYPLA2 | 0.65499 | 3 | 0 | 3 |
| DXO | LIPE | 0.651529 | 3 | 0 | 3 |
| DXO | MRPL2 | 0.648219 | 3 | 0 | 3 |
| DXO | LINC00665 | 0.637755 | 3 | 0 | 3 |
| DXO | IPO13 | 0.626993 | 3 | 0 | 3 |
| DXO | ZNF580 | 0.621445 | 4 | 0 | 3 |
| DXO | TBC1D13 | 0.615346 | 4 | 0 | 4 |
| DXO | SH2B1 | 0.60799 | 4 | 0 | 3 |
| DXO | C6orf136 | 0.60189 | 5 | 0 | 3 |
| DXO | VPS11 | 0.598664 | 4 | 0 | 4 |
| DXO | RNF167 | 0.593683 | 4 | 0 | 3 |
| DXO | CUTA | 0.589824 | 8 | 0 | 5 |
| DXO | OR11A1 | 0.588094 | 4 | 0 | 3 |
| DXO | LRCH4 | 0.585788 | 3 | 0 | 3 |
| DXO | DMWD | 0.58422 | 4 | 0 | 3 |
| DXO | INPP5E | 0.584143 | 3 | 0 | 3 |
| DXO | TMEM201 | 0.580681 | 4 | 0 | 3 |
For details and further investigation, click here
