| Full name: zinc finger protein 580 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 51157 | HGNC ID: HGNC:29473 | Ensembl Gene: ENSG00000213015 | OMIM ID: 617888 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF580:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF580 | 51157 | 220748_s_at | 0.1839 | 0.7589 | |
| GSE20347 | ZNF580 | 51157 | 220748_s_at | -0.0017 | 0.9939 | |
| GSE23400 | ZNF580 | 51157 | 220748_s_at | 0.0078 | 0.9288 | |
| GSE26886 | ZNF580 | 51157 | 220748_s_at | 1.1264 | 0.0000 | |
| GSE29001 | ZNF580 | 51157 | 220748_s_at | 0.0597 | 0.9144 | |
| GSE38129 | ZNF580 | 51157 | 220748_s_at | -0.1316 | 0.5075 | |
| GSE45670 | ZNF580 | 51157 | 220748_s_at | -0.1319 | 0.2328 | |
| GSE53622 | ZNF580 | 51157 | 64616 | -0.0334 | 0.6855 | |
| GSE53624 | ZNF580 | 51157 | 64616 | 0.0613 | 0.4578 | |
| GSE63941 | ZNF580 | 51157 | 220748_s_at | -0.6137 | 0.1380 | |
| GSE77861 | ZNF580 | 51157 | 220748_s_at | 0.0212 | 0.9315 | |
| GSE97050 | ZNF580 | 51157 | A_23_P164797 | -0.3106 | 0.2455 | |
| SRP007169 | ZNF580 | 51157 | RNAseq | 0.2377 | 0.6422 | |
| SRP008496 | ZNF580 | 51157 | RNAseq | 0.2363 | 0.5744 | |
| SRP064894 | ZNF580 | 51157 | RNAseq | 1.1327 | 0.0080 | |
| SRP133303 | ZNF580 | 51157 | RNAseq | -0.0613 | 0.7435 | |
| SRP159526 | ZNF580 | 51157 | RNAseq | 0.4877 | 0.1390 | |
| SRP193095 | ZNF580 | 51157 | RNAseq | 0.4140 | 0.0307 | |
| SRP219564 | ZNF580 | 51157 | RNAseq | -0.3406 | 0.4493 | |
| TCGA | ZNF580 | 51157 | RNAseq | -0.0672 | 0.2859 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF580 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF580:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF580 | 51157 | 3 | 4 | 23 | |
| GSE20123 | ZNF580 | 51157 | 3 | 3 | 24 | |
| GSE43470 | ZNF580 | 51157 | 3 | 9 | 31 | |
| GSE46452 | ZNF580 | 51157 | 45 | 1 | 13 | |
| GSE47630 | ZNF580 | 51157 | 8 | 6 | 26 | |
| GSE54993 | ZNF580 | 51157 | 17 | 4 | 49 | |
| GSE54994 | ZNF580 | 51157 | 4 | 13 | 36 | |
| GSE60625 | ZNF580 | 51157 | 9 | 0 | 2 | |
| GSE74703 | ZNF580 | 51157 | 3 | 6 | 27 | |
| GSE74704 | ZNF580 | 51157 | 3 | 1 | 16 | |
| TCGA | ZNF580 | 51157 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.
Somatic mutations of ZNF580:
Generating mutation plots.
Highly correlated genes for ZNF580:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF580 | C19orf25 | 0.720638 | 3 | 0 | 3 |
| ZNF580 | RHPN1 | 0.705109 | 3 | 0 | 3 |
| ZNF580 | FLRT1 | 0.695162 | 4 | 0 | 3 |
| ZNF580 | CDH15 | 0.690688 | 3 | 0 | 3 |
| ZNF580 | GRK6 | 0.685057 | 3 | 0 | 3 |
| ZNF580 | SFXN3 | 0.679313 | 3 | 0 | 3 |
| ZNF580 | DUSP15 | 0.678245 | 3 | 0 | 3 |
| ZNF580 | SPSB1 | 0.678048 | 3 | 0 | 3 |
| ZNF580 | FRS3 | 0.671965 | 4 | 0 | 4 |
| ZNF580 | LEFTY1 | 0.66953 | 3 | 0 | 3 |
| ZNF580 | SLC7A10 | 0.658642 | 4 | 0 | 3 |
| ZNF580 | ZNF805 | 0.658259 | 3 | 0 | 3 |
| ZNF580 | SCUBE1 | 0.657226 | 3 | 0 | 3 |
| ZNF580 | NTNG2 | 0.644495 | 4 | 0 | 4 |
| ZNF580 | SOX3 | 0.643668 | 3 | 0 | 3 |
| ZNF580 | ACSL6 | 0.642289 | 3 | 0 | 3 |
| ZNF580 | GAS6-AS1 | 0.637157 | 3 | 0 | 3 |
| ZNF580 | GPC5 | 0.636521 | 3 | 0 | 3 |
| ZNF580 | MAPK15 | 0.636169 | 3 | 0 | 3 |
| ZNF580 | CLCNKB | 0.634745 | 3 | 0 | 3 |
For details and further investigation, click here
