| Full name: proline rich coiled-coil 2A | Alias Symbol: G2|D6S51E | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 7916 | HGNC ID: HGNC:13918 | Ensembl Gene: ENSG00000204469 | OMIM ID: 142580 |
Screen Evidence:
| |||
Expression of PRRC2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRC2A | 7916 | 212081_x_at | 0.9222 | 0.0702 | |
| GSE20347 | PRRC2A | 7916 | 214201_x_at | 0.0456 | 0.6368 | |
| GSE23400 | PRRC2A | 7916 | 208132_x_at | 0.3017 | 0.0000 | |
| GSE26886 | PRRC2A | 7916 | 214201_x_at | 0.0102 | 0.9574 | |
| GSE29001 | PRRC2A | 7916 | 214201_x_at | -0.0476 | 0.8636 | |
| GSE38129 | PRRC2A | 7916 | 214201_x_at | 0.0678 | 0.4756 | |
| GSE45670 | PRRC2A | 7916 | 214201_x_at | 0.1491 | 0.0786 | |
| GSE53622 | PRRC2A | 7916 | 45878 | 0.4421 | 0.0000 | |
| GSE53624 | PRRC2A | 7916 | 45878 | 0.6241 | 0.0000 | |
| GSE63941 | PRRC2A | 7916 | 212081_x_at | 1.2052 | 0.0009 | |
| GSE77861 | PRRC2A | 7916 | 208132_x_at | 0.2165 | 0.1944 | |
| GSE97050 | PRRC2A | 7916 | A_24_P641130 | 0.3515 | 0.3346 | |
| SRP007169 | PRRC2A | 7916 | RNAseq | 1.4059 | 0.0007 | |
| SRP008496 | PRRC2A | 7916 | RNAseq | 0.9893 | 0.0001 | |
| SRP064894 | PRRC2A | 7916 | RNAseq | 0.3256 | 0.0778 | |
| SRP133303 | PRRC2A | 7916 | RNAseq | 0.2293 | 0.0888 | |
| SRP159526 | PRRC2A | 7916 | RNAseq | 0.4540 | 0.0705 | |
| SRP193095 | PRRC2A | 7916 | RNAseq | 0.5297 | 0.0000 | |
| SRP219564 | PRRC2A | 7916 | RNAseq | 0.2686 | 0.2541 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRRC2A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PRRC2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRC2A | 7916 | 5 | 1 | 24 | |
| GSE20123 | PRRC2A | 7916 | 5 | 1 | 24 | |
| GSE43470 | PRRC2A | 7916 | 5 | 1 | 37 | |
| GSE46452 | PRRC2A | 7916 | 1 | 10 | 48 | |
| GSE47630 | PRRC2A | 7916 | 7 | 4 | 29 | |
| GSE54993 | PRRC2A | 7916 | 2 | 1 | 67 | |
| GSE54994 | PRRC2A | 7916 | 11 | 4 | 38 | |
| GSE60625 | PRRC2A | 7916 | 0 | 1 | 10 | |
| GSE74703 | PRRC2A | 7916 | 5 | 0 | 31 | |
| GSE74704 | PRRC2A | 7916 | 2 | 0 | 18 | |
| TCGA | PRRC2A | 7916 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of PRRC2A:
Generating mutation plots.
Highly correlated genes for PRRC2A:
Showing top 20/978 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRC2A | NCBP2 | 0.796188 | 3 | 0 | 3 |
| PRRC2A | MRPL38 | 0.77968 | 3 | 0 | 3 |
| PRRC2A | PRR12 | 0.773572 | 3 | 0 | 3 |
| PRRC2A | RPL7L1 | 0.77318 | 3 | 0 | 3 |
| PRRC2A | DGCR8 | 0.765236 | 3 | 0 | 3 |
| PRRC2A | GGN | 0.738812 | 4 | 0 | 4 |
| PRRC2A | NDUFA3 | 0.736657 | 3 | 0 | 3 |
| PRRC2A | TRIM47 | 0.728599 | 3 | 0 | 3 |
| PRRC2A | PLAGL2 | 0.724839 | 3 | 0 | 3 |
| PRRC2A | SORBS3 | 0.723494 | 3 | 0 | 3 |
| PRRC2A | SAMD1 | 0.723117 | 7 | 0 | 6 |
| PRRC2A | AVP | 0.720227 | 4 | 0 | 4 |
| PRRC2A | PPP1CA | 0.716754 | 3 | 0 | 3 |
| PRRC2A | NXF1 | 0.706166 | 3 | 0 | 3 |
| PRRC2A | BCL7A | 0.706108 | 7 | 0 | 7 |
| PRRC2A | FBXO16 | 0.705266 | 3 | 0 | 3 |
| PRRC2A | MIER2 | 0.70405 | 5 | 0 | 3 |
| PRRC2A | TMEM63B | 0.703377 | 5 | 0 | 4 |
| PRRC2A | GATAD2B | 0.69958 | 4 | 0 | 4 |
| PRRC2A | PTPN6 | 0.698115 | 3 | 0 | 3 |
For details and further investigation, click here
