| Full name: tripartite motif containing 50 | Alias Symbol: FLJ32804 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 135892 | HGNC ID: HGNC:19017 | Ensembl Gene: ENSG00000146755 | OMIM ID: 612548 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM50 | 135892 | 1556554_at | -0.1791 | 0.3054 | |
| GSE26886 | TRIM50 | 135892 | 1556554_at | 0.1364 | 0.2204 | |
| GSE45670 | TRIM50 | 135892 | 1556554_at | -0.0426 | 0.7061 | |
| GSE53622 | TRIM50 | 135892 | 38647 | 0.7252 | 0.0000 | |
| GSE53624 | TRIM50 | 135892 | 38647 | 0.9366 | 0.0000 | |
| GSE63941 | TRIM50 | 135892 | 1556554_at | 0.3036 | 0.0314 | |
| GSE77861 | TRIM50 | 135892 | 231014_at | -0.1529 | 0.0513 | |
| GSE97050 | TRIM50 | 135892 | A_23_P308136 | 0.1910 | 0.3996 | |
| TCGA | TRIM50 | 135892 | RNAseq | -5.9634 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRIM50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM50 | 135892 | 12 | 1 | 17 | |
| GSE20123 | TRIM50 | 135892 | 11 | 1 | 18 | |
| GSE43470 | TRIM50 | 135892 | 3 | 2 | 38 | |
| GSE46452 | TRIM50 | 135892 | 12 | 0 | 47 | |
| GSE47630 | TRIM50 | 135892 | 7 | 2 | 31 | |
| GSE54993 | TRIM50 | 135892 | 2 | 7 | 61 | |
| GSE54994 | TRIM50 | 135892 | 13 | 3 | 37 | |
| GSE60625 | TRIM50 | 135892 | 0 | 0 | 11 | |
| GSE74703 | TRIM50 | 135892 | 3 | 1 | 32 | |
| GSE74704 | TRIM50 | 135892 | 7 | 1 | 12 | |
| TCGA | TRIM50 | 135892 | 45 | 7 | 44 |
Total number of gains: 115; Total number of losses: 25; Total Number of normals: 348.
Somatic mutations of TRIM50:
Generating mutation plots.
Highly correlated genes for TRIM50:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM50 | ZNF585A | 0.739774 | 3 | 0 | 3 |
| TRIM50 | UCHL5 | 0.714517 | 3 | 0 | 3 |
| TRIM50 | UQCRQ | 0.700575 | 3 | 0 | 3 |
| TRIM50 | GOT1 | 0.690553 | 3 | 0 | 3 |
| TRIM50 | DISC1 | 0.684308 | 3 | 0 | 3 |
| TRIM50 | COMMD1 | 0.674567 | 3 | 0 | 3 |
| TRIM50 | TMEM132C | 0.666132 | 3 | 0 | 3 |
| TRIM50 | ZNF287 | 0.66372 | 3 | 0 | 3 |
| TRIM50 | GRHPR | 0.653994 | 3 | 0 | 3 |
| TRIM50 | LINC00459 | 0.653894 | 3 | 0 | 3 |
| TRIM50 | SPAG7 | 0.6535 | 3 | 0 | 3 |
| TRIM50 | ZNF142 | 0.652833 | 3 | 0 | 3 |
| TRIM50 | ECEL1 | 0.652342 | 4 | 0 | 3 |
| TRIM50 | EVC2 | 0.648776 | 3 | 0 | 3 |
| TRIM50 | AVP | 0.648428 | 3 | 0 | 3 |
| TRIM50 | CLYBL | 0.647305 | 3 | 0 | 3 |
| TRIM50 | ZNF747 | 0.644329 | 3 | 0 | 3 |
| TRIM50 | EDF1 | 0.64222 | 3 | 0 | 3 |
| TRIM50 | RPS14 | 0.636758 | 3 | 0 | 3 |
| TRIM50 | COPE | 0.631638 | 3 | 0 | 3 |
For details and further investigation, click here
