| Full name: enoyl-CoA hydratase domain containing 2 | Alias Symbol: FLJ10948 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 55268 | HGNC ID: HGNC:23408 | Ensembl Gene: ENSG00000121310 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ECHDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECHDC2 | 55268 | 218552_at | -1.1800 | 0.0567 | |
| GSE20347 | ECHDC2 | 55268 | 218552_at | -1.6995 | 0.0000 | |
| GSE23400 | ECHDC2 | 55268 | 218552_at | -1.3782 | 0.0000 | |
| GSE26886 | ECHDC2 | 55268 | 218552_at | -1.4313 | 0.0002 | |
| GSE29001 | ECHDC2 | 55268 | 218552_at | -1.5857 | 0.0002 | |
| GSE38129 | ECHDC2 | 55268 | 218552_at | -1.6559 | 0.0000 | |
| GSE45670 | ECHDC2 | 55268 | 218552_at | -1.0193 | 0.0020 | |
| GSE53622 | ECHDC2 | 55268 | 20754 | -1.8727 | 0.0000 | |
| GSE53624 | ECHDC2 | 55268 | 20754 | -2.0020 | 0.0000 | |
| GSE63941 | ECHDC2 | 55268 | 218552_at | -1.4524 | 0.0979 | |
| GSE77861 | ECHDC2 | 55268 | 218552_at | -1.3638 | 0.0036 | |
| GSE97050 | ECHDC2 | 55268 | A_23_P200203 | -0.7283 | 0.1241 | |
| SRP007169 | ECHDC2 | 55268 | RNAseq | -3.7980 | 0.0000 | |
| SRP008496 | ECHDC2 | 55268 | RNAseq | -3.1225 | 0.0000 | |
| SRP064894 | ECHDC2 | 55268 | RNAseq | -1.4995 | 0.0000 | |
| SRP133303 | ECHDC2 | 55268 | RNAseq | -1.7567 | 0.0000 | |
| SRP159526 | ECHDC2 | 55268 | RNAseq | -1.3314 | 0.0008 | |
| SRP193095 | ECHDC2 | 55268 | RNAseq | -1.3598 | 0.0000 | |
| SRP219564 | ECHDC2 | 55268 | RNAseq | -1.1299 | 0.0129 | |
| TCGA | ECHDC2 | 55268 | RNAseq | -0.5700 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by ECHDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECHDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECHDC2 | 55268 | 3 | 4 | 23 | |
| GSE20123 | ECHDC2 | 55268 | 3 | 3 | 24 | |
| GSE43470 | ECHDC2 | 55268 | 5 | 2 | 36 | |
| GSE46452 | ECHDC2 | 55268 | 2 | 1 | 56 | |
| GSE47630 | ECHDC2 | 55268 | 8 | 4 | 28 | |
| GSE54993 | ECHDC2 | 55268 | 0 | 1 | 69 | |
| GSE54994 | ECHDC2 | 55268 | 11 | 2 | 40 | |
| GSE60625 | ECHDC2 | 55268 | 0 | 0 | 11 | |
| GSE74703 | ECHDC2 | 55268 | 4 | 1 | 31 | |
| GSE74704 | ECHDC2 | 55268 | 2 | 0 | 18 | |
| TCGA | ECHDC2 | 55268 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of ECHDC2:
Generating mutation plots.
Highly correlated genes for ECHDC2:
Showing top 20/1632 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECHDC2 | CGNL1 | 0.825916 | 7 | 0 | 7 |
| ECHDC2 | SASH1 | 0.820797 | 11 | 0 | 11 |
| ECHDC2 | KIAA1211L | 0.818905 | 6 | 0 | 6 |
| ECHDC2 | YPEL3 | 0.809089 | 7 | 0 | 7 |
| ECHDC2 | SHROOM3 | 0.808757 | 7 | 0 | 7 |
| ECHDC2 | GPD1L | 0.806281 | 11 | 0 | 11 |
| ECHDC2 | KAT2B | 0.805364 | 11 | 0 | 11 |
| ECHDC2 | FAM214A | 0.800379 | 6 | 0 | 6 |
| ECHDC2 | FAM219B | 0.798189 | 4 | 0 | 4 |
| ECHDC2 | SNORA68 | 0.796943 | 4 | 0 | 4 |
| ECHDC2 | LNX1 | 0.792829 | 7 | 0 | 7 |
| ECHDC2 | SCNN1B | 0.789935 | 10 | 0 | 10 |
| ECHDC2 | ARHGEF10L | 0.787412 | 12 | 0 | 11 |
| ECHDC2 | HPGD | 0.787263 | 12 | 0 | 11 |
| ECHDC2 | SLC10A5 | 0.778387 | 3 | 0 | 3 |
| ECHDC2 | CASC3 | 0.770083 | 3 | 0 | 3 |
| ECHDC2 | UBL3 | 0.769522 | 11 | 0 | 11 |
| ECHDC2 | CA13 | 0.768703 | 3 | 0 | 3 |
| ECHDC2 | CTTNBP2 | 0.76747 | 7 | 0 | 6 |
| ECHDC2 | SVIP | 0.766069 | 7 | 0 | 7 |
For details and further investigation, click here
