| Full name: cingulin like 1 | Alias Symbol: FLJ14957|JACOP|KIAA1749|PCING | ||
| Type: protein-coding gene | Cytoband: 15q21.3 | ||
| Entrez ID: 84952 | HGNC ID: HGNC:25931 | Ensembl Gene: ENSG00000128849 | OMIM ID: 607856 |
| Drug and gene relationship at DGIdb | |||
Expression of CGNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CGNL1 | 84952 | 225817_at | -2.0726 | 0.0438 | |
| GSE26886 | CGNL1 | 84952 | 225817_at | -4.2349 | 0.0000 | |
| GSE45670 | CGNL1 | 84952 | 225817_at | -1.8301 | 0.0046 | |
| GSE53622 | CGNL1 | 84952 | 10516 | -2.4708 | 0.0000 | |
| GSE53624 | CGNL1 | 84952 | 10516 | -2.8283 | 0.0000 | |
| GSE63941 | CGNL1 | 84952 | 225817_at | 0.7886 | 0.4515 | |
| GSE77861 | CGNL1 | 84952 | 225817_at | -2.5533 | 0.0036 | |
| GSE97050 | CGNL1 | 84952 | A_23_P163306 | -1.2974 | 0.0964 | |
| SRP007169 | CGNL1 | 84952 | RNAseq | -3.4493 | 0.0000 | |
| SRP008496 | CGNL1 | 84952 | RNAseq | -3.2167 | 0.0000 | |
| SRP064894 | CGNL1 | 84952 | RNAseq | -3.6416 | 0.0000 | |
| SRP133303 | CGNL1 | 84952 | RNAseq | -2.0043 | 0.0000 | |
| SRP159526 | CGNL1 | 84952 | RNAseq | -2.9109 | 0.0000 | |
| SRP193095 | CGNL1 | 84952 | RNAseq | -2.8088 | 0.0000 | |
| SRP219564 | CGNL1 | 84952 | RNAseq | -2.2189 | 0.0009 | |
| TCGA | CGNL1 | 84952 | RNAseq | -1.1677 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by CGNL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CGNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CGNL1 | 84952 | 6 | 4 | 20 | |
| GSE20123 | CGNL1 | 84952 | 6 | 3 | 21 | |
| GSE43470 | CGNL1 | 84952 | 4 | 4 | 35 | |
| GSE46452 | CGNL1 | 84952 | 3 | 7 | 49 | |
| GSE47630 | CGNL1 | 84952 | 8 | 10 | 22 | |
| GSE54993 | CGNL1 | 84952 | 5 | 6 | 59 | |
| GSE54994 | CGNL1 | 84952 | 6 | 8 | 39 | |
| GSE60625 | CGNL1 | 84952 | 4 | 0 | 7 | |
| GSE74703 | CGNL1 | 84952 | 4 | 3 | 29 | |
| GSE74704 | CGNL1 | 84952 | 2 | 3 | 15 | |
| TCGA | CGNL1 | 84952 | 10 | 16 | 70 |
Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.
Somatic mutations of CGNL1:
Generating mutation plots.
Highly correlated genes for CGNL1:
Showing top 20/1878 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CGNL1 | CAB39L | 0.884907 | 7 | 0 | 7 |
| CGNL1 | HPGD | 0.860441 | 7 | 0 | 7 |
| CGNL1 | CTTNBP2 | 0.857807 | 6 | 0 | 6 |
| CGNL1 | SORT1 | 0.857503 | 7 | 0 | 7 |
| CGNL1 | FAM214A | 0.855531 | 6 | 0 | 6 |
| CGNL1 | FNDC4 | 0.834679 | 6 | 0 | 6 |
| CGNL1 | ARHGEF10L | 0.833699 | 7 | 0 | 7 |
| CGNL1 | PADI1 | 0.831931 | 4 | 0 | 4 |
| CGNL1 | RMND5B | 0.830029 | 7 | 0 | 7 |
| CGNL1 | MGLL | 0.828526 | 7 | 0 | 7 |
| CGNL1 | SCNN1B | 0.828521 | 6 | 0 | 6 |
| CGNL1 | ECHDC2 | 0.825916 | 7 | 0 | 7 |
| CGNL1 | AIF1L | 0.825434 | 5 | 0 | 5 |
| CGNL1 | PAQR8 | 0.824921 | 7 | 0 | 7 |
| CGNL1 | SECISBP2L | 0.821699 | 7 | 0 | 7 |
| CGNL1 | GBP6 | 0.818 | 4 | 0 | 4 |
| CGNL1 | SIM2 | 0.817916 | 7 | 0 | 7 |
| CGNL1 | ACAA1 | 0.817615 | 4 | 0 | 4 |
| CGNL1 | STK39 | 0.817476 | 7 | 0 | 7 |
| CGNL1 | EPB41L3 | 0.817428 | 7 | 0 | 7 |
For details and further investigation, click here
