| Full name: transient receptor potential cation channel subfamily V member 5 | Alias Symbol: CaT2 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 56302 | HGNC ID: HGNC:3145 | Ensembl Gene: ENSG00000127412 | OMIM ID: 606679 |
| Drug and gene relationship at DGIdb | |||
TRPV5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04961 | Endocrine and other factor-regulated calcium reabsorption |
Expression of TRPV5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPV5 | 56302 | 208267_at | 0.0427 | 0.9096 | |
| GSE20347 | TRPV5 | 56302 | 208267_at | -0.0309 | 0.7327 | |
| GSE23400 | TRPV5 | 56302 | 208267_at | -0.1205 | 0.0011 | |
| GSE26886 | TRPV5 | 56302 | 208267_at | 0.0653 | 0.5651 | |
| GSE29001 | TRPV5 | 56302 | 208267_at | -0.2813 | 0.0645 | |
| GSE38129 | TRPV5 | 56302 | 208267_at | -0.1197 | 0.2531 | |
| GSE45670 | TRPV5 | 56302 | 208267_at | 0.1086 | 0.2947 | |
| GSE63941 | TRPV5 | 56302 | 208267_at | 0.1747 | 0.1712 | |
| GSE77861 | TRPV5 | 56302 | 208267_at | -0.0398 | 0.7212 | |
| TCGA | TRPV5 | 56302 | RNAseq | 0.8393 | 0.5803 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRPV5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TRPV5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPV5 | 56302 | 4 | 2 | 24 | |
| GSE20123 | TRPV5 | 56302 | 4 | 2 | 24 | |
| GSE43470 | TRPV5 | 56302 | 2 | 4 | 37 | |
| GSE46452 | TRPV5 | 56302 | 7 | 2 | 50 | |
| GSE47630 | TRPV5 | 56302 | 6 | 7 | 27 | |
| GSE54993 | TRPV5 | 56302 | 3 | 4 | 63 | |
| GSE54994 | TRPV5 | 56302 | 5 | 8 | 40 | |
| GSE60625 | TRPV5 | 56302 | 0 | 0 | 11 | |
| GSE74703 | TRPV5 | 56302 | 2 | 4 | 30 | |
| GSE74704 | TRPV5 | 56302 | 2 | 2 | 16 | |
| TCGA | TRPV5 | 56302 | 28 | 24 | 44 |
Total number of gains: 63; Total number of losses: 59; Total Number of normals: 366.
Somatic mutations of TRPV5:
Generating mutation plots.
Highly correlated genes for TRPV5:
Showing top 20/949 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPV5 | EDDM3A | 0.746585 | 3 | 0 | 3 |
| TRPV5 | CHRD | 0.712548 | 3 | 0 | 3 |
| TRPV5 | KLF15 | 0.710714 | 3 | 0 | 3 |
| TRPV5 | SLC28A2 | 0.705865 | 3 | 0 | 3 |
| TRPV5 | TNFRSF13B | 0.702962 | 5 | 0 | 5 |
| TRPV5 | CCL25 | 0.693319 | 5 | 0 | 5 |
| TRPV5 | CRYBB1 | 0.690304 | 6 | 0 | 6 |
| TRPV5 | EFR3B | 0.689527 | 4 | 0 | 4 |
| TRPV5 | SPTBN5 | 0.687103 | 3 | 0 | 3 |
| TRPV5 | CBL | 0.68653 | 3 | 0 | 3 |
| TRPV5 | C6 | 0.685863 | 3 | 0 | 3 |
| TRPV5 | DRD5 | 0.682894 | 4 | 0 | 4 |
| TRPV5 | MYOG | 0.672328 | 9 | 0 | 8 |
| TRPV5 | CEACAM3 | 0.671633 | 8 | 0 | 6 |
| TRPV5 | GJA8 | 0.664967 | 7 | 0 | 7 |
| TRPV5 | TTC9B | 0.663439 | 3 | 0 | 3 |
| TRPV5 | BTNL2 | 0.662451 | 5 | 0 | 4 |
| TRPV5 | CD5L | 0.661358 | 5 | 0 | 5 |
| TRPV5 | NOS1 | 0.660989 | 5 | 0 | 4 |
| TRPV5 | SPP2 | 0.660239 | 3 | 0 | 3 |
For details and further investigation, click here
