| Full name: hyaluronidase 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q31.32 | ||
| Entrez ID: 23553 | HGNC ID: HGNC:5323 | Ensembl Gene: ENSG00000106302 | OMIM ID: 604510 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HYAL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYAL4 | 23553 | 220249_at | 0.1016 | 0.8103 | |
| GSE20347 | HYAL4 | 23553 | 220249_at | -0.0092 | 0.8967 | |
| GSE23400 | HYAL4 | 23553 | 220249_at | 0.0371 | 0.2806 | |
| GSE26886 | HYAL4 | 23553 | 220249_at | -0.0701 | 0.5504 | |
| GSE29001 | HYAL4 | 23553 | 220249_at | -0.0734 | 0.7025 | |
| GSE38129 | HYAL4 | 23553 | 220249_at | -0.1006 | 0.2063 | |
| GSE45670 | HYAL4 | 23553 | 220249_at | 0.1229 | 0.2006 | |
| GSE53622 | HYAL4 | 23553 | 86166 | 0.4782 | 0.0034 | |
| GSE53624 | HYAL4 | 23553 | 86166 | 0.7463 | 0.0000 | |
| GSE63941 | HYAL4 | 23553 | 220249_at | 0.1636 | 0.3118 | |
| GSE77861 | HYAL4 | 23553 | 220249_at | -0.0890 | 0.3115 | |
| GSE97050 | HYAL4 | 23553 | A_33_P3421984 | 0.6208 | 0.0950 | |
| SRP133303 | HYAL4 | 23553 | RNAseq | -0.0875 | 0.7375 | |
| TCGA | HYAL4 | 23553 | RNAseq | 2.1175 | 0.0151 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HYAL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYAL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYAL4 | 23553 | 6 | 2 | 22 | |
| GSE20123 | HYAL4 | 23553 | 7 | 2 | 21 | |
| GSE43470 | HYAL4 | 23553 | 2 | 4 | 37 | |
| GSE46452 | HYAL4 | 23553 | 8 | 1 | 50 | |
| GSE47630 | HYAL4 | 23553 | 7 | 4 | 29 | |
| GSE54993 | HYAL4 | 23553 | 3 | 5 | 62 | |
| GSE54994 | HYAL4 | 23553 | 9 | 7 | 37 | |
| GSE60625 | HYAL4 | 23553 | 0 | 0 | 11 | |
| GSE74703 | HYAL4 | 23553 | 2 | 4 | 30 | |
| GSE74704 | HYAL4 | 23553 | 5 | 2 | 13 | |
| TCGA | HYAL4 | 23553 | 27 | 21 | 48 |
Total number of gains: 76; Total number of losses: 52; Total Number of normals: 360.
Somatic mutations of HYAL4:
Generating mutation plots.
Highly correlated genes for HYAL4:
Showing top 20/407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYAL4 | LINC01281 | 0.702582 | 4 | 0 | 4 |
| HYAL4 | EDDM3A | 0.697437 | 4 | 0 | 4 |
| HYAL4 | LINC00460 | 0.690687 | 3 | 0 | 3 |
| HYAL4 | SOX15 | 0.678493 | 3 | 0 | 3 |
| HYAL4 | FAM153A | 0.671104 | 5 | 0 | 5 |
| HYAL4 | WNT10A | 0.670327 | 3 | 0 | 3 |
| HYAL4 | KLK2 | 0.661823 | 4 | 0 | 3 |
| HYAL4 | GJB1 | 0.652354 | 6 | 0 | 5 |
| HYAL4 | DEFA4 | 0.646326 | 5 | 0 | 4 |
| HYAL4 | SLC2A5 | 0.643114 | 4 | 0 | 4 |
| HYAL4 | CDRT15 | 0.636899 | 3 | 0 | 3 |
| HYAL4 | CIITA | 0.636341 | 5 | 0 | 5 |
| HYAL4 | UCMA | 0.635424 | 3 | 0 | 3 |
| HYAL4 | TFAP4 | 0.634432 | 4 | 0 | 4 |
| HYAL4 | OR10J1 | 0.633622 | 6 | 0 | 5 |
| HYAL4 | NDOR1 | 0.626023 | 5 | 0 | 4 |
| HYAL4 | COX6B2 | 0.623434 | 4 | 0 | 3 |
| HYAL4 | HUNK | 0.622364 | 4 | 0 | 3 |
| HYAL4 | C8A | 0.620839 | 5 | 0 | 4 |
| HYAL4 | LRRC8A | 0.61996 | 3 | 0 | 3 |
For details and further investigation, click here
