OR2F1

 

Full name: olfactory receptor family 2 subfamily F member 1 (gene/pseudogene) Alias Symbol: OLF3|OR7-140|OR7-139|OR14-60
Type: protein-coding gene Cytoband: 7q35
Entrez ID: 26211 HGNC ID: HGNC:8246 Ensembl Gene: ENSG00000213215 OMIM ID: 608497
Drug and gene relationship at DGIdb

 

OR2F1 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2F1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2F1 26211 208526_at -0.0223 0.9491
GSE20347 OR2F1 26211 208526_at -0.1156 0.0521
GSE23400 OR2F1 26211 208526_at -0.1066 0.0016
GSE26886 OR2F1 26211 208526_at 0.0654 0.5776
GSE29001 OR2F1 26211 208526_at -0.1067 0.3223
GSE38129 OR2F1 26211 208526_at -0.0940 0.1551
GSE45670 OR2F1 26211 208526_at 0.3540 0.0005
GSE63941 OR2F1 26211 208526_at 0.0532 0.7954
GSE77861 OR2F1 26211 208526_at -0.0144 0.8957
GSE97050 OR2F1 26211 A_23_P8716 -0.0726 0.8218

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR2F1 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of OR2F1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2F1 26211 3 2 25
GSE20123 OR2F1 26211 3 2 25
GSE43470 OR2F1 26211 3 4 36
GSE46452 OR2F1 26211 7 2 50
GSE47630 OR2F1 26211 6 8 26
GSE54993 OR2F1 26211 3 4 63
GSE54994 OR2F1 26211 5 8 40
GSE60625 OR2F1 26211 0 0 11
GSE74703 OR2F1 26211 2 4 30
GSE74704 OR2F1 26211 1 2 17
TCGA OR2F1 26211 27 26 43

Total number of gains: 60; Total number of losses: 62; Total Number of normals: 366.  


 

Somatic mutations of OR2F1:

 

Generating mutation plots.

 

Highly correlated genes for OR2F1:

 

Showing top 20/323 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2F1AVP0.723147303
OR2F1MUC60.719938303
OR2F1EFR3B0.713931403
OR2F1DUSP180.68205303
OR2F1HEYL0.681815404
OR2F1DDX520.681786303
OR2F1SHB0.681561303
OR2F1AMPD30.67889403
OR2F1ZC3H180.663499303
OR2F1PTPRA0.662363303
OR2F1SIRPG0.662169403
OR2F1OR7A100.660221404
OR2F1GRK10.655576303
OR2F1PHLDB10.65237504
OR2F1ZNF7100.652239504
OR2F1BAIAP30.651444303
OR2F1MVK0.650064504
OR2F1APOA40.645496404
OR2F1MTA30.644984303
OR2F1CCIN0.642353504

For details and further investigation, click here