| Full name: TNF superfamily member 9 | Alias Symbol: 4-1BB-L|4-1BBL | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 8744 | HGNC ID: HGNC:11939 | Ensembl Gene: ENSG00000125657 | OMIM ID: 606182 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFSF9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFSF9 | 8744 | 206907_at | -1.0516 | 0.1657 | |
| GSE20347 | TNFSF9 | 8744 | 206907_at | 0.3112 | 0.0072 | |
| GSE23400 | TNFSF9 | 8744 | 206907_at | 0.1208 | 0.0403 | |
| GSE26886 | TNFSF9 | 8744 | 206907_at | -0.0121 | 0.9640 | |
| GSE29001 | TNFSF9 | 8744 | 206907_at | 0.2041 | 0.5553 | |
| GSE38129 | TNFSF9 | 8744 | 206907_at | 0.3940 | 0.0675 | |
| GSE45670 | TNFSF9 | 8744 | 206907_at | 0.4090 | 0.1550 | |
| GSE53622 | TNFSF9 | 8744 | 2630 | 0.3462 | 0.0982 | |
| GSE53624 | TNFSF9 | 8744 | 2630 | 0.6176 | 0.0000 | |
| GSE63941 | TNFSF9 | 8744 | 206907_at | 1.0783 | 0.1850 | |
| GSE77861 | TNFSF9 | 8744 | 206907_at | 0.0952 | 0.4248 | |
| GSE97050 | TNFSF9 | 8744 | A_33_P3397763 | 0.2155 | 0.4952 | |
| SRP007169 | TNFSF9 | 8744 | RNAseq | 0.6098 | 0.3484 | |
| SRP064894 | TNFSF9 | 8744 | RNAseq | 0.2466 | 0.4944 | |
| SRP133303 | TNFSF9 | 8744 | RNAseq | 0.2592 | 0.4687 | |
| SRP159526 | TNFSF9 | 8744 | RNAseq | -0.1987 | 0.6243 | |
| SRP219564 | TNFSF9 | 8744 | RNAseq | 0.9646 | 0.2381 | |
| TCGA | TNFSF9 | 8744 | RNAseq | 1.1707 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TNFSF9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFSF9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFSF9 | 8744 | 5 | 3 | 22 | |
| GSE20123 | TNFSF9 | 8744 | 4 | 2 | 24 | |
| GSE43470 | TNFSF9 | 8744 | 2 | 6 | 35 | |
| GSE46452 | TNFSF9 | 8744 | 47 | 1 | 11 | |
| GSE47630 | TNFSF9 | 8744 | 5 | 7 | 28 | |
| GSE54993 | TNFSF9 | 8744 | 16 | 3 | 51 | |
| GSE54994 | TNFSF9 | 8744 | 6 | 14 | 33 | |
| GSE60625 | TNFSF9 | 8744 | 9 | 0 | 2 | |
| GSE74703 | TNFSF9 | 8744 | 2 | 4 | 30 | |
| GSE74704 | TNFSF9 | 8744 | 1 | 2 | 17 | |
| TCGA | TNFSF9 | 8744 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of TNFSF9:
Generating mutation plots.
Highly correlated genes for TNFSF9:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFSF9 | EFR3B | 0.835487 | 3 | 0 | 3 |
| TNFSF9 | OR7A10 | 0.714743 | 3 | 0 | 3 |
| TNFSF9 | POLD4 | 0.705808 | 3 | 0 | 3 |
| TNFSF9 | GPR3 | 0.694144 | 3 | 0 | 3 |
| TNFSF9 | SLC29A1 | 0.688849 | 3 | 0 | 3 |
| TNFSF9 | UTY | 0.683478 | 3 | 0 | 3 |
| TNFSF9 | TRIM15 | 0.664895 | 3 | 0 | 3 |
| TNFSF9 | KLHL17 | 0.64896 | 4 | 0 | 3 |
| TNFSF9 | TMEM132C | 0.64844 | 4 | 0 | 3 |
| TNFSF9 | MRPS25 | 0.64011 | 3 | 0 | 3 |
| TNFSF9 | METRNL | 0.639498 | 3 | 0 | 3 |
| TNFSF9 | TNFSF14 | 0.636108 | 4 | 0 | 4 |
| TNFSF9 | SLC35A4 | 0.625653 | 3 | 0 | 3 |
| TNFSF9 | GRIN3B | 0.623897 | 4 | 0 | 3 |
| TNFSF9 | UBE2D2 | 0.623775 | 4 | 0 | 3 |
| TNFSF9 | MIDN | 0.62189 | 3 | 0 | 3 |
| TNFSF9 | PPFIBP1 | 0.617778 | 3 | 0 | 3 |
| TNFSF9 | ADAMTS10 | 0.615597 | 5 | 0 | 4 |
| TNFSF9 | SLC5A2 | 0.612675 | 3 | 0 | 3 |
| TNFSF9 | SH2D3C | 0.605544 | 4 | 0 | 3 |
For details and further investigation, click here
