| Full name: embryonal Fyn-associated substrate | Alias Symbol: EFS2|EFS1|HEFS|SIN|CASS3 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 10278 | HGNC ID: HGNC:16898 | Ensembl Gene: ENSG00000100842 | OMIM ID: 609906 |
| Drug and gene relationship at DGIdb | |||
Expression of EFS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFS | 10278 | 204400_at | 0.0503 | 0.9774 | |
| GSE20347 | EFS | 10278 | 204400_at | -0.1355 | 0.5293 | |
| GSE23400 | EFS | 10278 | 204400_at | 0.1856 | 0.1251 | |
| GSE26886 | EFS | 10278 | 204400_at | 0.4810 | 0.0224 | |
| GSE29001 | EFS | 10278 | 204400_at | 0.2739 | 0.4360 | |
| GSE38129 | EFS | 10278 | 204400_at | 0.0277 | 0.9196 | |
| GSE45670 | EFS | 10278 | 204400_at | 0.3170 | 0.1659 | |
| GSE53622 | EFS | 10278 | 15967 | 0.0952 | 0.3912 | |
| GSE53624 | EFS | 10278 | 15967 | 0.0020 | 0.9824 | |
| GSE63941 | EFS | 10278 | 204400_at | -0.5652 | 0.6937 | |
| GSE77861 | EFS | 10278 | 204400_at | -0.0114 | 0.9814 | |
| GSE97050 | EFS | 10278 | A_23_P48561 | -0.1506 | 0.5999 | |
| SRP007169 | EFS | 10278 | RNAseq | -0.1885 | 0.6588 | |
| SRP008496 | EFS | 10278 | RNAseq | -0.2611 | 0.4250 | |
| SRP064894 | EFS | 10278 | RNAseq | 0.0628 | 0.7716 | |
| SRP133303 | EFS | 10278 | RNAseq | -0.2213 | 0.3805 | |
| SRP159526 | EFS | 10278 | RNAseq | 0.1546 | 0.5876 | |
| SRP219564 | EFS | 10278 | RNAseq | -0.0127 | 0.9804 | |
| TCGA | EFS | 10278 | RNAseq | 0.5087 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EFS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFS | 10278 | 9 | 1 | 20 | |
| GSE20123 | EFS | 10278 | 9 | 1 | 20 | |
| GSE43470 | EFS | 10278 | 7 | 2 | 34 | |
| GSE46452 | EFS | 10278 | 17 | 2 | 40 | |
| GSE47630 | EFS | 10278 | 11 | 10 | 19 | |
| GSE54993 | EFS | 10278 | 3 | 11 | 56 | |
| GSE54994 | EFS | 10278 | 18 | 5 | 30 | |
| GSE60625 | EFS | 10278 | 0 | 2 | 9 | |
| GSE74703 | EFS | 10278 | 6 | 2 | 28 | |
| GSE74704 | EFS | 10278 | 4 | 1 | 15 | |
| TCGA | EFS | 10278 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of EFS:
Generating mutation plots.
Highly correlated genes for EFS:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFS | MYO1C | 0.752854 | 3 | 0 | 3 |
| EFS | KCP | 0.738613 | 3 | 0 | 3 |
| EFS | CCDC142 | 0.731316 | 4 | 0 | 3 |
| EFS | PNMA6A | 0.721947 | 3 | 0 | 3 |
| EFS | CPAMD8 | 0.697891 | 3 | 0 | 3 |
| EFS | RASEF | 0.674484 | 3 | 0 | 3 |
| EFS | DOHH | 0.656624 | 3 | 0 | 3 |
| EFS | FBRSL1 | 0.650882 | 4 | 0 | 3 |
| EFS | IL17RE | 0.64961 | 4 | 0 | 3 |
| EFS | WDPCP | 0.648346 | 4 | 0 | 3 |
| EFS | EFNA3 | 0.629981 | 4 | 0 | 3 |
| EFS | CDK13 | 0.626997 | 5 | 0 | 3 |
| EFS | RIN1 | 0.625185 | 5 | 0 | 4 |
| EFS | SYCE1L | 0.621611 | 3 | 0 | 3 |
| EFS | SDR42E1 | 0.612879 | 3 | 0 | 3 |
| EFS | KIFC2 | 0.611119 | 4 | 0 | 3 |
| EFS | KLRG2 | 0.594687 | 4 | 0 | 3 |
| EFS | CCDC152 | 0.589278 | 4 | 0 | 3 |
| EFS | HAUS5 | 0.589191 | 4 | 0 | 3 |
| EFS | C19orf81 | 0.586905 | 4 | 0 | 3 |
For details and further investigation, click here
