| Full name: short chain dehydrogenase/reductase family 42E, member 1 | Alias Symbol: HSPC105 | ||
| Type: protein-coding gene | Cytoband: 16q23.3 | ||
| Entrez ID: 93517 | HGNC ID: HGNC:29834 | Ensembl Gene: ENSG00000184860 | OMIM ID: 616164 |
| Drug and gene relationship at DGIdb | |||
Expression of SDR42E1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDR42E1 | 93517 | 229522_at | 0.0901 | 0.8437 | |
| GSE26886 | SDR42E1 | 93517 | 229522_at | -0.8229 | 0.0010 | |
| GSE45670 | SDR42E1 | 93517 | 241356_at | -0.0694 | 0.8426 | |
| GSE53622 | SDR42E1 | 93517 | 1313 | -0.6134 | 0.0161 | |
| GSE53624 | SDR42E1 | 93517 | 1313 | -0.1804 | 0.2105 | |
| GSE63941 | SDR42E1 | 93517 | 229522_at | 1.3522 | 0.0720 | |
| GSE77861 | SDR42E1 | 93517 | 229522_at | -0.2660 | 0.2689 | |
| GSE97050 | SDR42E1 | 93517 | A_23_P129458 | 0.3067 | 0.3382 | |
| SRP007169 | SDR42E1 | 93517 | RNAseq | -0.4533 | 0.6279 | |
| SRP008496 | SDR42E1 | 93517 | RNAseq | -0.5819 | 0.5135 | |
| SRP064894 | SDR42E1 | 93517 | RNAseq | -0.5002 | 0.1084 | |
| SRP133303 | SDR42E1 | 93517 | RNAseq | -1.0534 | 0.0118 | |
| SRP159526 | SDR42E1 | 93517 | RNAseq | -0.1505 | 0.6406 | |
| SRP193095 | SDR42E1 | 93517 | RNAseq | -0.3119 | 0.0921 | |
| SRP219564 | SDR42E1 | 93517 | RNAseq | -0.4304 | 0.5514 | |
| TCGA | SDR42E1 | 93517 | RNAseq | -0.0050 | 0.9801 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SDR42E1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDR42E1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDR42E1 | 93517 | 5 | 2 | 23 | |
| GSE20123 | SDR42E1 | 93517 | 5 | 2 | 23 | |
| GSE43470 | SDR42E1 | 93517 | 2 | 8 | 33 | |
| GSE46452 | SDR42E1 | 93517 | 37 | 2 | 20 | |
| GSE47630 | SDR42E1 | 93517 | 11 | 9 | 20 | |
| GSE54993 | SDR42E1 | 93517 | 2 | 4 | 64 | |
| GSE54994 | SDR42E1 | 93517 | 7 | 10 | 36 | |
| GSE60625 | SDR42E1 | 93517 | 4 | 0 | 7 | |
| GSE74703 | SDR42E1 | 93517 | 2 | 6 | 28 | |
| GSE74704 | SDR42E1 | 93517 | 3 | 2 | 15 | |
| TCGA | SDR42E1 | 93517 | 25 | 15 | 56 |
Total number of gains: 103; Total number of losses: 60; Total Number of normals: 325.
Somatic mutations of SDR42E1:
Generating mutation plots.
Highly correlated genes for SDR42E1:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDR42E1 | IL17RE | 0.745692 | 3 | 0 | 3 |
| SDR42E1 | EXOSC7 | 0.710681 | 3 | 0 | 3 |
| SDR42E1 | KCNK7 | 0.699386 | 3 | 0 | 3 |
| SDR42E1 | TSPAN13 | 0.697103 | 3 | 0 | 3 |
| SDR42E1 | PPP1R13B | 0.674567 | 3 | 0 | 3 |
| SDR42E1 | SHQ1 | 0.660624 | 3 | 0 | 3 |
| SDR42E1 | ATAD3C | 0.658958 | 3 | 0 | 3 |
| SDR42E1 | UNC13B | 0.657233 | 3 | 0 | 3 |
| SDR42E1 | RUSC1 | 0.651587 | 3 | 0 | 3 |
| SDR42E1 | ARHGAP5-AS1 | 0.638411 | 3 | 0 | 3 |
| SDR42E1 | NPY2R | 0.627361 | 4 | 0 | 4 |
| SDR42E1 | PFN4 | 0.62407 | 3 | 0 | 3 |
| SDR42E1 | OTUB2 | 0.619928 | 3 | 0 | 3 |
| SDR42E1 | CARD6 | 0.619253 | 4 | 0 | 3 |
| SDR42E1 | HPSE | 0.614363 | 4 | 0 | 4 |
| SDR42E1 | DGAT2 | 0.612903 | 4 | 0 | 3 |
| SDR42E1 | EFS | 0.612879 | 3 | 0 | 3 |
| SDR42E1 | SULT2B1 | 0.604566 | 4 | 0 | 3 |
| SDR42E1 | L2HGDH | 0.604317 | 3 | 0 | 3 |
| SDR42E1 | SH2D1B | 0.604201 | 3 | 0 | 3 |
For details and further investigation, click here
