MYO1C

 

Full name: myosin IC Alias Symbol: myr2
Type: protein-coding gene Cytoband: 17p13.3
Entrez ID: 4641 HGNC ID: HGNC:7597 Ensembl Gene: ENSG00000197879 OMIM ID: 606538
Drug and gene relationship at DGIdb

 

Expression of MYO1C:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MYO1C 4641 214656_x_at -0.1681 0.7623
GSE20347 MYO1C 4641 214656_x_at 0.1568 0.2177
GSE23400 MYO1C 4641 214656_x_at -0.0164 0.7990
GSE26886 MYO1C 4641 214656_x_at 0.4493 0.0296
GSE29001 MYO1C 4641 214656_x_at -0.1910 0.5736
GSE38129 MYO1C 4641 214656_x_at -0.1704 0.1950
GSE45670 MYO1C 4641 214656_x_at 0.0288 0.8240
GSE53622 MYO1C 4641 88043 0.1548 0.0241
GSE53624 MYO1C 4641 88043 0.0928 0.1241
GSE63941 MYO1C 4641 214656_x_at -0.9474 0.0079
GSE77861 MYO1C 4641 214656_x_at 0.1992 0.3650
GSE97050 MYO1C 4641 A_23_P164022 -0.1861 0.4312
SRP007169 MYO1C 4641 RNAseq -0.4742 0.1746
SRP008496 MYO1C 4641 RNAseq -0.3460 0.1044
SRP064894 MYO1C 4641 RNAseq 0.2514 0.0841
SRP133303 MYO1C 4641 RNAseq -0.1364 0.4777
SRP159526 MYO1C 4641 RNAseq -0.1606 0.3682
SRP193095 MYO1C 4641 RNAseq 0.2161 0.0685
SRP219564 MYO1C 4641 RNAseq -0.2756 0.4641
TCGA MYO1C 4641 RNAseq -0.1544 0.0003

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MYO1C expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MYO1C:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MYO1C 4641 5 2 23
GSE20123 MYO1C 4641 5 3 22
GSE43470 MYO1C 4641 3 6 34
GSE46452 MYO1C 4641 34 1 24
GSE47630 MYO1C 4641 8 1 31
GSE54993 MYO1C 4641 9 3 58
GSE54994 MYO1C 4641 7 9 37
GSE60625 MYO1C 4641 4 0 7
GSE74703 MYO1C 4641 2 3 31
GSE74704 MYO1C 4641 3 1 16
TCGA MYO1C 4641 19 21 56

Total number of gains: 99; Total number of losses: 50; Total Number of normals: 339.  


 

Somatic mutations of MYO1C:

 

Generating mutation plots.

 

Highly correlated genes for MYO1C:

 

Showing top 20/174 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MYO1CRBM430.858172404
MYO1CZNF7630.855326303
MYO1CYY20.790072303
MYO1CMOB1B0.781673303
MYO1CEFS0.752854303
MYO1CGJD40.739742403
MYO1CMRGPRG0.736112303
MYO1CSIRPA0.73359303
MYO1CC9orf1530.733326303
MYO1CINSC0.730448303
MYO1CIGLON50.726239303
MYO1CPRSS380.726171303
MYO1COR2B110.724374303
MYO1CLBX20.722334303
MYO1COR10AD10.718029303
MYO1CTMEM2350.717696303
MYO1CPAX60.712604303
MYO1CDCDC10.710072303
MYO1CPHAX0.702146404
MYO1COR2T10.701134303

For details and further investigation, click here