| Full name: synaptonemal complex central element protein 1 like | Alias Symbol: MRP2 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 100130958 | HGNC ID: HGNC:37236 | Ensembl Gene: ENSG00000205078 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SYCE1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCE1L | 100130958 | 1559960_x_at | 0.2261 | 0.6799 | |
| GSE20347 | SYCE1L | 100130958 | 215301_at | 0.1043 | 0.1070 | |
| GSE23400 | SYCE1L | 100130958 | 215301_at | 0.0605 | 0.1370 | |
| GSE26886 | SYCE1L | 100130958 | 1559960_x_at | 1.4683 | 0.0000 | |
| GSE29001 | SYCE1L | 100130958 | 215301_at | 0.2553 | 0.5912 | |
| GSE38129 | SYCE1L | 100130958 | 215301_at | 0.0755 | 0.1238 | |
| GSE45670 | SYCE1L | 100130958 | 1559960_x_at | -0.0675 | 0.6475 | |
| GSE53622 | SYCE1L | 100130958 | 124133 | 0.2565 | 0.0026 | |
| GSE53624 | SYCE1L | 100130958 | 124133 | 0.6070 | 0.0000 | |
| GSE63941 | SYCE1L | 100130958 | 1559960_x_at | 0.3779 | 0.4354 | |
| GSE77861 | SYCE1L | 100130958 | 1559960_x_at | -0.0623 | 0.7337 | |
| GSE97050 | SYCE1L | 100130958 | A_33_P3314673 | -0.1386 | 0.4853 | |
| SRP133303 | SYCE1L | 100130958 | RNAseq | -0.1735 | 0.5587 | |
| SRP159526 | SYCE1L | 100130958 | RNAseq | 0.1937 | 0.5752 | |
| SRP219564 | SYCE1L | 100130958 | RNAseq | 0.1033 | 0.7992 | |
| TCGA | SYCE1L | 100130958 | RNAseq | 1.4002 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SYCE1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYCE1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCE1L | 100130958 | 3 | 2 | 25 | |
| GSE20123 | SYCE1L | 100130958 | 3 | 2 | 25 | |
| GSE43470 | SYCE1L | 100130958 | 2 | 8 | 33 | |
| GSE46452 | SYCE1L | 100130958 | 37 | 2 | 20 | |
| GSE47630 | SYCE1L | 100130958 | 11 | 8 | 21 | |
| GSE54993 | SYCE1L | 100130958 | 2 | 4 | 64 | |
| GSE54994 | SYCE1L | 100130958 | 7 | 11 | 35 | |
| GSE60625 | SYCE1L | 100130958 | 4 | 0 | 7 | |
| GSE74703 | SYCE1L | 100130958 | 2 | 6 | 28 | |
| GSE74704 | SYCE1L | 100130958 | 2 | 1 | 17 | |
| TCGA | SYCE1L | 100130958 | 25 | 14 | 57 |
Total number of gains: 98; Total number of losses: 58; Total Number of normals: 332.
Somatic mutations of SYCE1L:
Generating mutation plots.
Highly correlated genes for SYCE1L:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCE1L | ARL8A | 0.809909 | 3 | 0 | 3 |
| SYCE1L | GTF2IRD2 | 0.763564 | 3 | 0 | 3 |
| SYCE1L | KLRG2 | 0.757229 | 3 | 0 | 3 |
| SYCE1L | CEACAM20 | 0.752183 | 3 | 0 | 3 |
| SYCE1L | ATXN7L2 | 0.743805 | 3 | 0 | 3 |
| SYCE1L | MRPS2 | 0.741686 | 3 | 0 | 3 |
| SYCE1L | ENPP1 | 0.740147 | 3 | 0 | 3 |
| SYCE1L | DSCAM | 0.738248 | 3 | 0 | 3 |
| SYCE1L | ZNF511 | 0.733923 | 3 | 0 | 3 |
| SYCE1L | ASPDH | 0.72591 | 3 | 0 | 3 |
| SYCE1L | MAPK15 | 0.719351 | 3 | 0 | 3 |
| SYCE1L | FAM53A | 0.718227 | 3 | 0 | 3 |
| SYCE1L | ASMTL | 0.716715 | 4 | 0 | 3 |
| SYCE1L | SCUBE1 | 0.71349 | 3 | 0 | 3 |
| SYCE1L | CPAMD8 | 0.711506 | 5 | 0 | 5 |
| SYCE1L | FBRSL1 | 0.710766 | 4 | 0 | 4 |
| SYCE1L | ZBTB48 | 0.704197 | 4 | 0 | 4 |
| SYCE1L | CACNB3 | 0.703797 | 4 | 0 | 4 |
| SYCE1L | PNMA6A | 0.701168 | 3 | 0 | 3 |
| SYCE1L | ZMYND15 | 0.697539 | 4 | 0 | 4 |
For details and further investigation, click here
