HAUS5

 

Full name: HAUS augmin like complex subunit 5 Alias Symbol: dgt5
Type: protein-coding gene Cytoband: 19q13.12
Entrez ID: 23354 HGNC ID: HGNC:29130 Ensembl Gene: ENSG00000249115 OMIM ID: 613432
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of HAUS5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HAUS5 23354 36888_at 0.1170 0.7051
GSE20347 HAUS5 23354 36888_at 0.3604 0.0285
GSE23400 HAUS5 23354 36888_at 0.1057 0.0030
GSE26886 HAUS5 23354 36888_at -0.0725 0.7453
GSE29001 HAUS5 23354 36888_at 0.3590 0.2387
GSE38129 HAUS5 23354 36888_at 0.2546 0.0725
GSE45670 HAUS5 23354 36888_at 0.1362 0.3507
GSE53622 HAUS5 23354 48357 0.1190 0.0084
GSE53624 HAUS5 23354 48357 0.2743 0.0001
GSE63941 HAUS5 23354 36888_at 1.1772 0.0134
GSE77861 HAUS5 23354 213053_at 0.1124 0.4647
GSE97050 HAUS5 23354 A_33_P3269338 0.2077 0.3445
SRP007169 HAUS5 23354 RNAseq 1.8274 0.0098
SRP008496 HAUS5 23354 RNAseq 0.1086 0.6834
SRP064894 HAUS5 23354 RNAseq 0.8385 0.0017
SRP133303 HAUS5 23354 RNAseq 0.2473 0.2147
SRP159526 HAUS5 23354 RNAseq 1.0672 0.0402
SRP193095 HAUS5 23354 RNAseq 0.5293 0.0001
SRP219564 HAUS5 23354 RNAseq 0.3586 0.2685
TCGA HAUS5 23354 RNAseq 0.3280 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by HAUS5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of HAUS5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HAUS5 23354 6 4 20
GSE20123 HAUS5 23354 6 3 21
GSE43470 HAUS5 23354 3 7 33
GSE46452 HAUS5 23354 48 1 10
GSE47630 HAUS5 23354 9 5 26
GSE54993 HAUS5 23354 17 3 50
GSE54994 HAUS5 23354 7 9 37
GSE60625 HAUS5 23354 9 0 2
GSE74703 HAUS5 23354 3 4 29
GSE74704 HAUS5 23354 6 1 13
TCGA HAUS5 23354 22 10 64

Total number of gains: 136; Total number of losses: 47; Total Number of normals: 305.  


 

Somatic mutations of HAUS5:

 

Generating mutation plots.

 

Highly correlated genes for HAUS5:

 

Showing top 20/288 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HAUS5CNOT30.75235303
HAUS5LRFN10.739268303
HAUS5SPATA2L0.737347303
HAUS5FGFR40.714307303
HAUS5SIGLEC50.709033303
HAUS5ZNF4460.703888505
HAUS5KCNAB30.696301404
HAUS5ACR0.6942403
HAUS5ARL8A0.694034303
HAUS5LMF10.693545303
HAUS5GPR1820.692706403
HAUS5GDPD50.690465404
HAUS5HRG0.687018303
HAUS5MFSD100.685292303
HAUS5MYO15B0.6851303
HAUS5UBE2S0.684311303
HAUS5CACNG40.682923504
HAUS5CCDC330.682328403
HAUS5HECW10.678804505
HAUS5TMEM63A0.678562303

For details and further investigation, click here