| Full name: EGF like, fibronectin type III and laminin G domains | Alias Symbol: FLJ39155|AGRINL|AGRNL|PIKA | ||
| Type: protein-coding gene | Cytoband: 5p13.2-p13.1 | ||
| Entrez ID: 133584 | HGNC ID: HGNC:26810 | Ensembl Gene: ENSG00000164318 | OMIM ID: 617683 |
| Drug and gene relationship at DGIdb | |||
Expression of EGFLAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EGFLAM | 133584 | 226911_at | 0.1078 | 0.9002 | |
| GSE26886 | EGFLAM | 133584 | 226911_at | 0.2324 | 0.2248 | |
| GSE45670 | EGFLAM | 133584 | 226911_at | 0.1324 | 0.5372 | |
| GSE53622 | EGFLAM | 133584 | 70889 | 0.6920 | 0.0000 | |
| GSE53624 | EGFLAM | 133584 | 70889 | 0.7867 | 0.0000 | |
| GSE63941 | EGFLAM | 133584 | 226911_at | -0.0842 | 0.9210 | |
| GSE77861 | EGFLAM | 133584 | 226911_at | 0.1206 | 0.2495 | |
| GSE97050 | EGFLAM | 133584 | A_23_P144911 | 0.2089 | 0.5960 | |
| SRP007169 | EGFLAM | 133584 | RNAseq | 1.9770 | 0.0250 | |
| SRP064894 | EGFLAM | 133584 | RNAseq | 1.4586 | 0.0001 | |
| SRP133303 | EGFLAM | 133584 | RNAseq | 0.1407 | 0.5047 | |
| SRP159526 | EGFLAM | 133584 | RNAseq | 1.7095 | 0.0046 | |
| SRP193095 | EGFLAM | 133584 | RNAseq | 1.2614 | 0.0000 | |
| SRP219564 | EGFLAM | 133584 | RNAseq | -0.3149 | 0.7084 | |
| TCGA | EGFLAM | 133584 | RNAseq | 0.1155 | 0.5069 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by EGFLAM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EGFLAM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EGFLAM | 133584 | 10 | 0 | 20 | |
| GSE20123 | EGFLAM | 133584 | 10 | 0 | 20 | |
| GSE43470 | EGFLAM | 133584 | 18 | 0 | 25 | |
| GSE46452 | EGFLAM | 133584 | 5 | 22 | 32 | |
| GSE47630 | EGFLAM | 133584 | 6 | 12 | 22 | |
| GSE54993 | EGFLAM | 133584 | 5 | 4 | 61 | |
| GSE54994 | EGFLAM | 133584 | 25 | 2 | 26 | |
| GSE60625 | EGFLAM | 133584 | 0 | 0 | 11 | |
| GSE74703 | EGFLAM | 133584 | 14 | 0 | 22 | |
| GSE74704 | EGFLAM | 133584 | 9 | 0 | 11 | |
| TCGA | EGFLAM | 133584 | 52 | 6 | 38 |
Total number of gains: 154; Total number of losses: 46; Total Number of normals: 288.
Somatic mutations of EGFLAM:
Generating mutation plots.
Highly correlated genes for EGFLAM:
Showing top 20/391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EGFLAM | CNTLN | 0.765931 | 3 | 0 | 3 |
| EGFLAM | RAB34 | 0.749722 | 3 | 0 | 3 |
| EGFLAM | HEXA | 0.725902 | 3 | 0 | 3 |
| EGFLAM | ICAM1 | 0.724049 | 4 | 0 | 3 |
| EGFLAM | CCL8 | 0.723347 | 3 | 0 | 3 |
| EGFLAM | FEZ1 | 0.717643 | 4 | 0 | 3 |
| EGFLAM | PROX1 | 0.696799 | 3 | 0 | 3 |
| EGFLAM | ARHGAP24 | 0.696598 | 3 | 0 | 3 |
| EGFLAM | BSN | 0.693188 | 3 | 0 | 3 |
| EGFLAM | ING1 | 0.692158 | 3 | 0 | 3 |
| EGFLAM | CCDC127 | 0.691548 | 3 | 0 | 3 |
| EGFLAM | FBXO31 | 0.689875 | 3 | 0 | 3 |
| EGFLAM | SEMA3A | 0.688573 | 3 | 0 | 3 |
| EGFLAM | RGS3 | 0.686593 | 5 | 0 | 4 |
| EGFLAM | RAB11FIP3 | 0.685651 | 4 | 0 | 3 |
| EGFLAM | DMXL2 | 0.685369 | 4 | 0 | 3 |
| EGFLAM | NFKBID | 0.684597 | 3 | 0 | 3 |
| EGFLAM | RELL1 | 0.679166 | 3 | 0 | 3 |
| EGFLAM | EFCAB7 | 0.677148 | 3 | 0 | 3 |
| EGFLAM | DCHS1 | 0.674801 | 3 | 0 | 3 |
For details and further investigation, click here
