| Full name: eukaryotic translation initiation factor 3 subunit A | Alias Symbol: eIF3-theta|eIF3-p170|KIAA0139|eIF3a|TIF32 | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 8661 | HGNC ID: HGNC:3271 | Ensembl Gene: ENSG00000107581 | OMIM ID: 602039 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3A | 8661 | 200595_s_at | -0.0361 | 0.9354 | |
| GSE20347 | EIF3A | 8661 | 200595_s_at | -0.0924 | 0.4636 | |
| GSE23400 | EIF3A | 8661 | 200595_s_at | -0.0161 | 0.8603 | |
| GSE26886 | EIF3A | 8661 | 200595_s_at | -0.3721 | 0.1145 | |
| GSE29001 | EIF3A | 8661 | 200595_s_at | -0.0952 | 0.7332 | |
| GSE38129 | EIF3A | 8661 | 200595_s_at | -0.0776 | 0.4522 | |
| GSE45670 | EIF3A | 8661 | 200595_s_at | -0.0905 | 0.3059 | |
| GSE53622 | EIF3A | 8661 | 30880 | -0.2420 | 0.0000 | |
| GSE53624 | EIF3A | 8661 | 30880 | -0.1778 | 0.0000 | |
| GSE63941 | EIF3A | 8661 | 200595_s_at | -0.2764 | 0.4555 | |
| GSE77861 | EIF3A | 8661 | 200595_s_at | -0.0015 | 0.9956 | |
| GSE97050 | EIF3A | 8661 | A_23_P86550 | -0.3368 | 0.1694 | |
| SRP007169 | EIF3A | 8661 | RNAseq | -0.1370 | 0.7256 | |
| SRP008496 | EIF3A | 8661 | RNAseq | -0.0014 | 0.9944 | |
| SRP064894 | EIF3A | 8661 | RNAseq | -0.5883 | 0.0064 | |
| SRP133303 | EIF3A | 8661 | RNAseq | -0.0714 | 0.5931 | |
| SRP159526 | EIF3A | 8661 | RNAseq | -0.3425 | 0.3408 | |
| SRP193095 | EIF3A | 8661 | RNAseq | -0.2084 | 0.0298 | |
| SRP219564 | EIF3A | 8661 | RNAseq | -0.3853 | 0.1179 | |
| TCGA | EIF3A | 8661 | RNAseq | -0.0941 | 0.0104 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3A | 8661 | 2 | 8 | 20 | |
| GSE20123 | EIF3A | 8661 | 2 | 8 | 20 | |
| GSE43470 | EIF3A | 8661 | 0 | 9 | 34 | |
| GSE46452 | EIF3A | 8661 | 0 | 11 | 48 | |
| GSE47630 | EIF3A | 8661 | 2 | 14 | 24 | |
| GSE54993 | EIF3A | 8661 | 8 | 0 | 62 | |
| GSE54994 | EIF3A | 8661 | 1 | 11 | 41 | |
| GSE60625 | EIF3A | 8661 | 0 | 0 | 11 | |
| GSE74703 | EIF3A | 8661 | 0 | 6 | 30 | |
| GSE74704 | EIF3A | 8661 | 1 | 3 | 16 | |
| TCGA | EIF3A | 8661 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 98; Total Number of normals: 370.
Somatic mutations of EIF3A:
Generating mutation plots.
Highly correlated genes for EIF3A:
Showing top 20/467 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3A | ZNF644 | 0.745688 | 3 | 0 | 3 |
| EIF3A | MRPL13 | 0.728303 | 3 | 0 | 3 |
| EIF3A | PITRM1 | 0.727518 | 3 | 0 | 3 |
| EIF3A | UBE3C | 0.724906 | 3 | 0 | 3 |
| EIF3A | C2CD2 | 0.723835 | 3 | 0 | 3 |
| EIF3A | APIP | 0.72038 | 3 | 0 | 3 |
| EIF3A | ZSCAN29 | 0.707045 | 3 | 0 | 3 |
| EIF3A | PTGES3 | 0.706854 | 3 | 0 | 3 |
| EIF3A | COPS5 | 0.705449 | 3 | 0 | 3 |
| EIF3A | SLC35A5 | 0.690208 | 4 | 0 | 4 |
| EIF3A | VPS37B | 0.689392 | 3 | 0 | 3 |
| EIF3A | PSMD7 | 0.687878 | 3 | 0 | 3 |
| EIF3A | ACSL3 | 0.686983 | 3 | 0 | 3 |
| EIF3A | PPP1R2 | 0.685269 | 3 | 0 | 3 |
| EIF3A | SERINC1 | 0.681814 | 4 | 0 | 3 |
| EIF3A | C5orf51 | 0.677536 | 3 | 0 | 3 |
| EIF3A | SMU1 | 0.676217 | 3 | 0 | 3 |
| EIF3A | SOCS5 | 0.674674 | 3 | 0 | 3 |
| EIF3A | ZNF416 | 0.673662 | 3 | 0 | 3 |
| EIF3A | UPF2 | 0.668635 | 4 | 0 | 4 |
For details and further investigation, click here
