| Full name: APAF1 interacting protein | Alias Symbol: CGI-29|Mmrp19|APIP2 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 51074 | HGNC ID: HGNC:17581 | Ensembl Gene: ENSG00000149089 | OMIM ID: 612491 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of APIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APIP | 51074 | 218698_at | -0.6749 | 0.0828 | |
| GSE20347 | APIP | 51074 | 218698_at | -0.3508 | 0.0464 | |
| GSE23400 | APIP | 51074 | 218698_at | 0.0698 | 0.4105 | |
| GSE26886 | APIP | 51074 | 218698_at | -0.3693 | 0.1489 | |
| GSE29001 | APIP | 51074 | 218698_at | 0.0861 | 0.8275 | |
| GSE38129 | APIP | 51074 | 218698_at | -0.3430 | 0.0176 | |
| GSE45670 | APIP | 51074 | 218698_at | -0.3186 | 0.0243 | |
| GSE53622 | APIP | 51074 | 27664 | -0.2333 | 0.0069 | |
| GSE53624 | APIP | 51074 | 27664 | -0.2146 | 0.0618 | |
| GSE63941 | APIP | 51074 | 218698_at | -0.2822 | 0.6572 | |
| GSE77861 | APIP | 51074 | 218698_at | -0.5331 | 0.0480 | |
| GSE97050 | APIP | 51074 | A_23_P2066 | -0.2617 | 0.2538 | |
| SRP007169 | APIP | 51074 | RNAseq | 0.1973 | 0.6376 | |
| SRP008496 | APIP | 51074 | RNAseq | 0.0091 | 0.9722 | |
| SRP064894 | APIP | 51074 | RNAseq | 0.3023 | 0.3111 | |
| SRP133303 | APIP | 51074 | RNAseq | -0.0122 | 0.9313 | |
| SRP159526 | APIP | 51074 | RNAseq | -0.2014 | 0.5897 | |
| SRP193095 | APIP | 51074 | RNAseq | -0.5199 | 0.0001 | |
| SRP219564 | APIP | 51074 | RNAseq | -0.2718 | 0.4422 | |
| TCGA | APIP | 51074 | RNAseq | -0.2553 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by APIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APIP | 51074 | 1 | 8 | 21 | |
| GSE20123 | APIP | 51074 | 1 | 7 | 22 | |
| GSE43470 | APIP | 51074 | 4 | 4 | 35 | |
| GSE46452 | APIP | 51074 | 7 | 5 | 47 | |
| GSE47630 | APIP | 51074 | 3 | 10 | 27 | |
| GSE54993 | APIP | 51074 | 3 | 2 | 65 | |
| GSE54994 | APIP | 51074 | 3 | 10 | 40 | |
| GSE60625 | APIP | 51074 | 0 | 0 | 11 | |
| GSE74703 | APIP | 51074 | 3 | 2 | 31 | |
| GSE74704 | APIP | 51074 | 0 | 4 | 16 | |
| TCGA | APIP | 51074 | 16 | 23 | 57 |
Total number of gains: 41; Total number of losses: 75; Total Number of normals: 372.
Somatic mutations of APIP:
Generating mutation plots.
Highly correlated genes for APIP:
Showing top 20/631 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APIP | EIF1AY | 0.80968 | 3 | 0 | 3 |
| APIP | ZFP36L2 | 0.787063 | 3 | 0 | 3 |
| APIP | EVC2 | 0.783289 | 3 | 0 | 3 |
| APIP | ATF1 | 0.777885 | 3 | 0 | 3 |
| APIP | TPPP | 0.769506 | 3 | 0 | 3 |
| APIP | MAPK9 | 0.744732 | 3 | 0 | 3 |
| APIP | MFAP1 | 0.74429 | 3 | 0 | 3 |
| APIP | KCNG2 | 0.743199 | 3 | 0 | 3 |
| APIP | TSPAN31 | 0.742771 | 3 | 0 | 3 |
| APIP | GPCPD1 | 0.736308 | 3 | 0 | 3 |
| APIP | MAML2 | 0.731508 | 3 | 0 | 3 |
| APIP | KLHDC8B | 0.724263 | 3 | 0 | 3 |
| APIP | EIF3A | 0.72038 | 3 | 0 | 3 |
| APIP | MRPS35 | 0.714344 | 3 | 0 | 3 |
| APIP | SMG8 | 0.714302 | 3 | 0 | 3 |
| APIP | RASGEF1B | 0.712481 | 3 | 0 | 3 |
| APIP | CLDN2 | 0.708712 | 3 | 0 | 3 |
| APIP | SLC46A2 | 0.708106 | 3 | 0 | 3 |
| APIP | LDB3 | 0.707117 | 3 | 0 | 3 |
| APIP | PAIP2 | 0.706764 | 4 | 0 | 4 |
For details and further investigation, click here
