| Full name: mitochondrial ribosomal protein L13 | Alias Symbol: L13|RPL13|L13mt|RPML13|L13A | ||
| Type: protein-coding gene | Cytoband: 8q24.12 | ||
| Entrez ID: 28998 | HGNC ID: HGNC:14278 | Ensembl Gene: ENSG00000172172 | OMIM ID: 610200 |
| Drug and gene relationship at DGIdb | |||
Expression of MRPL13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL13 | 28998 | 218049_s_at | 0.6499 | 0.1325 | |
| GSE20347 | MRPL13 | 28998 | 218049_s_at | 0.5426 | 0.0210 | |
| GSE23400 | MRPL13 | 28998 | 218049_s_at | 0.8499 | 0.0000 | |
| GSE26886 | MRPL13 | 28998 | 218049_s_at | 0.1718 | 0.5953 | |
| GSE29001 | MRPL13 | 28998 | 218049_s_at | 0.3391 | 0.6048 | |
| GSE38129 | MRPL13 | 28998 | 218049_s_at | 0.7943 | 0.0000 | |
| GSE45670 | MRPL13 | 28998 | 218049_s_at | 0.6180 | 0.0002 | |
| GSE53622 | MRPL13 | 28998 | 16936 | 0.7777 | 0.0000 | |
| GSE53624 | MRPL13 | 28998 | 7197 | 0.7073 | 0.0000 | |
| GSE63941 | MRPL13 | 28998 | 218049_s_at | 1.2017 | 0.0158 | |
| GSE77861 | MRPL13 | 28998 | 218049_s_at | 0.0846 | 0.7824 | |
| GSE97050 | MRPL13 | 28998 | A_23_P44974 | 0.3360 | 0.2682 | |
| SRP007169 | MRPL13 | 28998 | RNAseq | 0.0113 | 0.9748 | |
| SRP008496 | MRPL13 | 28998 | RNAseq | 0.0157 | 0.9370 | |
| SRP064894 | MRPL13 | 28998 | RNAseq | 0.7394 | 0.0019 | |
| SRP133303 | MRPL13 | 28998 | RNAseq | 0.7236 | 0.0001 | |
| SRP159526 | MRPL13 | 28998 | RNAseq | 0.2031 | 0.5256 | |
| SRP193095 | MRPL13 | 28998 | RNAseq | 0.0457 | 0.8159 | |
| SRP219564 | MRPL13 | 28998 | RNAseq | 0.2047 | 0.4452 | |
| TCGA | MRPL13 | 28998 | RNAseq | 0.2692 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL13 | 28998 | 19 | 1 | 10 | |
| GSE20123 | MRPL13 | 28998 | 20 | 1 | 9 | |
| GSE43470 | MRPL13 | 28998 | 23 | 0 | 20 | |
| GSE46452 | MRPL13 | 28998 | 27 | 0 | 32 | |
| GSE47630 | MRPL13 | 28998 | 24 | 0 | 16 | |
| GSE54993 | MRPL13 | 28998 | 0 | 20 | 50 | |
| GSE54994 | MRPL13 | 28998 | 38 | 0 | 15 | |
| GSE60625 | MRPL13 | 28998 | 0 | 4 | 7 | |
| GSE74703 | MRPL13 | 28998 | 19 | 0 | 17 | |
| GSE74704 | MRPL13 | 28998 | 13 | 1 | 6 | |
| TCGA | MRPL13 | 28998 | 66 | 3 | 27 |
Total number of gains: 249; Total number of losses: 30; Total Number of normals: 209.
Somatic mutations of MRPL13:
Generating mutation plots.
Highly correlated genes for MRPL13:
Showing top 20/1555 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL13 | TP53RK | 0.830574 | 3 | 0 | 3 |
| MRPL13 | ZNF707 | 0.813056 | 3 | 0 | 3 |
| MRPL13 | CCDC85C | 0.799 | 3 | 0 | 3 |
| MRPL13 | KIF3A | 0.787986 | 3 | 0 | 3 |
| MRPL13 | AP1AR | 0.765502 | 3 | 0 | 3 |
| MRPL13 | TIAL1 | 0.763772 | 3 | 0 | 3 |
| MRPL13 | RLIM | 0.761552 | 3 | 0 | 3 |
| MRPL13 | CENPBD1 | 0.755103 | 3 | 0 | 3 |
| MRPL13 | POLR2K | 0.751079 | 10 | 0 | 9 |
| MRPL13 | CLSPN | 0.743902 | 4 | 0 | 4 |
| MRPL13 | NOA1 | 0.740221 | 3 | 0 | 3 |
| MRPL13 | DCAF13 | 0.734445 | 8 | 0 | 7 |
| MRPL13 | KTI12 | 0.73358 | 3 | 0 | 3 |
| MRPL13 | MRPS28 | 0.733063 | 11 | 0 | 8 |
| MRPL13 | ATP6V1C1 | 0.731581 | 12 | 0 | 12 |
| MRPL13 | EIF3A | 0.728303 | 3 | 0 | 3 |
| MRPL13 | C8orf76 | 0.725082 | 8 | 0 | 7 |
| MRPL13 | NAA15 | 0.72449 | 3 | 0 | 3 |
| MRPL13 | MRPL15 | 0.723132 | 11 | 0 | 11 |
| MRPL13 | EMG1 | 0.722297 | 9 | 0 | 9 |
For details and further investigation, click here
