| Full name: sine oculis binding protein homolog | Alias Symbol: FLJ10159 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 55084 | HGNC ID: HGNC:29256 | Ensembl Gene: ENSG00000112320 | OMIM ID: 613667 |
| Drug and gene relationship at DGIdb | |||
Expression of SOBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOBP | 55084 | 218974_at | -0.9924 | 0.3865 | |
| GSE20347 | SOBP | 55084 | 218974_at | 0.1338 | 0.7459 | |
| GSE23400 | SOBP | 55084 | 218974_at | -0.4970 | 0.0147 | |
| GSE26886 | SOBP | 55084 | 218974_at | 1.9798 | 0.0011 | |
| GSE29001 | SOBP | 55084 | 218974_at | -0.1933 | 0.7565 | |
| GSE38129 | SOBP | 55084 | 218974_at | -0.7103 | 0.1786 | |
| GSE45670 | SOBP | 55084 | 218974_at | -2.0746 | 0.0000 | |
| GSE53622 | SOBP | 55084 | 35532 | -0.7839 | 0.0000 | |
| GSE53624 | SOBP | 55084 | 81325 | -0.6274 | 0.0001 | |
| GSE63941 | SOBP | 55084 | 218974_at | -2.2006 | 0.0370 | |
| GSE77861 | SOBP | 55084 | 229034_at | -0.1076 | 0.2319 | |
| GSE97050 | SOBP | 55084 | A_33_P3363485 | -0.9879 | 0.1399 | |
| SRP007169 | SOBP | 55084 | RNAseq | 5.4597 | 0.0001 | |
| SRP064894 | SOBP | 55084 | RNAseq | 0.1072 | 0.7943 | |
| SRP133303 | SOBP | 55084 | RNAseq | -0.3745 | 0.4019 | |
| SRP159526 | SOBP | 55084 | RNAseq | 0.2620 | 0.6557 | |
| SRP193095 | SOBP | 55084 | RNAseq | 0.7456 | 0.0540 | |
| SRP219564 | SOBP | 55084 | RNAseq | -0.5796 | 0.5900 | |
| TCGA | SOBP | 55084 | RNAseq | -0.8126 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by SOBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOBP | 55084 | 2 | 3 | 25 | |
| GSE20123 | SOBP | 55084 | 2 | 2 | 26 | |
| GSE43470 | SOBP | 55084 | 3 | 1 | 39 | |
| GSE46452 | SOBP | 55084 | 2 | 11 | 46 | |
| GSE47630 | SOBP | 55084 | 9 | 4 | 27 | |
| GSE54993 | SOBP | 55084 | 3 | 2 | 65 | |
| GSE54994 | SOBP | 55084 | 8 | 8 | 37 | |
| GSE60625 | SOBP | 55084 | 0 | 2 | 9 | |
| GSE74703 | SOBP | 55084 | 2 | 1 | 33 | |
| GSE74704 | SOBP | 55084 | 0 | 0 | 20 | |
| TCGA | SOBP | 55084 | 5 | 23 | 68 |
Total number of gains: 36; Total number of losses: 57; Total Number of normals: 395.
Somatic mutations of SOBP:
Generating mutation plots.
Highly correlated genes for SOBP:
Showing top 20/1069 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOBP | TCEAL6 | 0.801055 | 3 | 0 | 3 |
| SOBP | C1QTNF7 | 0.784398 | 5 | 0 | 5 |
| SOBP | EPHA3 | 0.783255 | 6 | 0 | 6 |
| SOBP | RASSF3 | 0.77764 | 4 | 0 | 4 |
| SOBP | TCEAL5 | 0.775068 | 3 | 0 | 3 |
| SOBP | MYADM | 0.775037 | 4 | 0 | 4 |
| SOBP | FIBIN | 0.774528 | 4 | 0 | 4 |
| SOBP | RBMX2 | 0.774015 | 3 | 0 | 3 |
| SOBP | FXYD6 | 0.771659 | 10 | 0 | 10 |
| SOBP | JAM3 | 0.770434 | 12 | 0 | 12 |
| SOBP | ANAPC16 | 0.770354 | 3 | 0 | 3 |
| SOBP | KANK2 | 0.762211 | 10 | 0 | 9 |
| SOBP | FNDC5 | 0.758198 | 4 | 0 | 4 |
| SOBP | MSRB3 | 0.757914 | 7 | 0 | 7 |
| SOBP | DCHS1 | 0.757101 | 9 | 0 | 9 |
| SOBP | RRAS | 0.755412 | 6 | 0 | 6 |
| SOBP | CASQ2 | 0.755254 | 8 | 0 | 8 |
| SOBP | CFL2 | 0.752291 | 5 | 0 | 5 |
| SOBP | MYOCD | 0.751045 | 5 | 0 | 5 |
| SOBP | EIF3G | 0.750076 | 3 | 0 | 3 |
For details and further investigation, click here
