| Full name: glutamyl-tRNA amidotransferase subunit C | Alias Symbol: FLJ37000|15E1.2|gatC | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 283459 | HGNC ID: HGNC:25068 | Ensembl Gene: ENSG00000257218 | OMIM ID: 617210 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GATC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GATC | 283459 | 225430_at | 0.0335 | 0.9307 | |
| GSE20347 | GATC | 283459 | 214711_at | 0.4135 | 0.0531 | |
| GSE23400 | GATC | 283459 | 214711_at | 0.1074 | 0.0024 | |
| GSE26886 | GATC | 283459 | 225430_at | 1.1991 | 0.0000 | |
| GSE29001 | GATC | 283459 | 214711_at | 0.3033 | 0.0498 | |
| GSE38129 | GATC | 283459 | 214711_at | 0.4932 | 0.0082 | |
| GSE45670 | GATC | 283459 | 225430_at | 0.0523 | 0.6879 | |
| GSE53622 | GATC | 283459 | 47414 | 0.0405 | 0.5158 | |
| GSE53624 | GATC | 283459 | 47414 | 0.2815 | 0.0000 | |
| GSE63941 | GATC | 283459 | 214711_at | 2.4918 | 0.0001 | |
| GSE77861 | GATC | 283459 | 225430_at | 0.1576 | 0.5060 | |
| GSE97050 | GATC | 283459 | A_23_P76435 | 0.1217 | 0.7114 | |
| SRP007169 | GATC | 283459 | RNAseq | 0.6804 | 0.0551 | |
| SRP008496 | GATC | 283459 | RNAseq | 1.0197 | 0.0000 | |
| SRP064894 | GATC | 283459 | RNAseq | 0.1999 | 0.0294 | |
| SRP133303 | GATC | 283459 | RNAseq | 0.2297 | 0.0724 | |
| SRP159526 | GATC | 283459 | RNAseq | 0.3735 | 0.1316 | |
| SRP193095 | GATC | 283459 | RNAseq | -0.0255 | 0.7502 | |
| SRP219564 | GATC | 283459 | RNAseq | 0.1188 | 0.6724 | |
| TCGA | GATC | 283459 | RNAseq | 0.2203 | 0.0223 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GATC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GATC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GATC | 283459 | 6 | 2 | 22 | |
| GSE20123 | GATC | 283459 | 6 | 2 | 22 | |
| GSE43470 | GATC | 283459 | 2 | 2 | 39 | |
| GSE46452 | GATC | 283459 | 9 | 1 | 49 | |
| GSE47630 | GATC | 283459 | 9 | 3 | 28 | |
| GSE54993 | GATC | 283459 | 0 | 5 | 65 | |
| GSE54994 | GATC | 283459 | 7 | 6 | 40 | |
| GSE60625 | GATC | 283459 | 0 | 0 | 11 | |
| GSE74703 | GATC | 283459 | 2 | 1 | 33 | |
| GSE74704 | GATC | 283459 | 3 | 2 | 15 | |
| TCGA | GATC | 283459 | 21 | 10 | 65 |
Total number of gains: 65; Total number of losses: 34; Total Number of normals: 389.
Somatic mutations of GATC:
Generating mutation plots.
Highly correlated genes for GATC:
Showing top 20/666 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GATC | EIF3G | 0.844501 | 3 | 0 | 3 |
| GATC | ZSCAN21 | 0.841057 | 3 | 0 | 3 |
| GATC | TSNARE1 | 0.835535 | 3 | 0 | 3 |
| GATC | INPP5K | 0.784309 | 3 | 0 | 3 |
| GATC | RRNAD1 | 0.774557 | 3 | 0 | 3 |
| GATC | PPP1R35 | 0.765566 | 3 | 0 | 3 |
| GATC | ATR | 0.758151 | 4 | 0 | 4 |
| GATC | RILPL1 | 0.752039 | 3 | 0 | 3 |
| GATC | LNP1 | 0.750193 | 3 | 0 | 3 |
| GATC | GRAMD1A | 0.739283 | 3 | 0 | 3 |
| GATC | EIF2D | 0.737945 | 3 | 0 | 3 |
| GATC | ZFAND2A | 0.737265 | 3 | 0 | 3 |
| GATC | ZNF484 | 0.733601 | 3 | 0 | 3 |
| GATC | GMCL1 | 0.729909 | 3 | 0 | 3 |
| GATC | RPAP1 | 0.729852 | 3 | 0 | 3 |
| GATC | DEDD | 0.72807 | 3 | 0 | 3 |
| GATC | ZNF418 | 0.728055 | 3 | 0 | 3 |
| GATC | A2M-AS1 | 0.727185 | 3 | 0 | 3 |
| GATC | F11R | 0.722061 | 3 | 0 | 3 |
| GATC | ZNF496 | 0.719919 | 3 | 0 | 3 |
For details and further investigation, click here
