| Full name: DnaJ heat shock protein family (Hsp40) member C3 | Alias Symbol: P58|P58IPK|HP58|ERdj6 | ||
| Type: protein-coding gene | Cytoband: 13q32.1 | ||
| Entrez ID: 5611 | HGNC ID: HGNC:9439 | Ensembl Gene: ENSG00000102580 | OMIM ID: 601184 |
| Drug and gene relationship at DGIdb | |||
DNAJC3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05164 | Influenza A |
Expression of DNAJC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC3 | 5611 | 225284_at | 0.1935 | 0.6788 | |
| GSE20347 | DNAJC3 | 5611 | 208499_s_at | -0.2067 | 0.1249 | |
| GSE23400 | DNAJC3 | 5611 | 208499_s_at | -0.1080 | 0.0456 | |
| GSE26886 | DNAJC3 | 5611 | 225284_at | -0.8074 | 0.0080 | |
| GSE29001 | DNAJC3 | 5611 | 208499_s_at | -0.3741 | 0.3262 | |
| GSE38129 | DNAJC3 | 5611 | 208499_s_at | 0.0817 | 0.5627 | |
| GSE45670 | DNAJC3 | 5611 | 225284_at | 0.1583 | 0.4026 | |
| GSE53622 | DNAJC3 | 5611 | 135738 | -0.0875 | 0.2977 | |
| GSE53624 | DNAJC3 | 5611 | 135738 | 0.0483 | 0.5095 | |
| GSE63941 | DNAJC3 | 5611 | 225284_at | -1.4540 | 0.0060 | |
| GSE77861 | DNAJC3 | 5611 | 225284_at | -0.1838 | 0.4752 | |
| GSE97050 | DNAJC3 | 5611 | A_33_P3462960 | 0.2828 | 0.4979 | |
| SRP007169 | DNAJC3 | 5611 | RNAseq | -0.6230 | 0.0914 | |
| SRP008496 | DNAJC3 | 5611 | RNAseq | -0.4574 | 0.0312 | |
| SRP064894 | DNAJC3 | 5611 | RNAseq | 0.0199 | 0.8965 | |
| SRP133303 | DNAJC3 | 5611 | RNAseq | 0.2567 | 0.1196 | |
| SRP159526 | DNAJC3 | 5611 | RNAseq | -0.1173 | 0.7405 | |
| SRP193095 | DNAJC3 | 5611 | RNAseq | -0.3319 | 0.0490 | |
| SRP219564 | DNAJC3 | 5611 | RNAseq | 0.4699 | 0.1436 | |
| TCGA | DNAJC3 | 5611 | RNAseq | -0.2271 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAJC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC3 | 5611 | 4 | 9 | 17 | |
| GSE20123 | DNAJC3 | 5611 | 4 | 8 | 18 | |
| GSE43470 | DNAJC3 | 5611 | 2 | 12 | 29 | |
| GSE46452 | DNAJC3 | 5611 | 0 | 32 | 27 | |
| GSE47630 | DNAJC3 | 5611 | 3 | 27 | 10 | |
| GSE54993 | DNAJC3 | 5611 | 11 | 3 | 56 | |
| GSE54994 | DNAJC3 | 5611 | 3 | 13 | 37 | |
| GSE60625 | DNAJC3 | 5611 | 0 | 3 | 8 | |
| GSE74703 | DNAJC3 | 5611 | 2 | 10 | 24 | |
| GSE74704 | DNAJC3 | 5611 | 2 | 8 | 10 | |
| TCGA | DNAJC3 | 5611 | 13 | 34 | 49 |
Total number of gains: 44; Total number of losses: 159; Total Number of normals: 285.
Somatic mutations of DNAJC3:
Generating mutation plots.
Highly correlated genes for DNAJC3:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC3 | SLC30A9 | 0.770525 | 3 | 0 | 3 |
| DNAJC3 | METTL14 | 0.755299 | 3 | 0 | 3 |
| DNAJC3 | NFXL1 | 0.737903 | 3 | 0 | 3 |
| DNAJC3 | FAF2 | 0.735672 | 3 | 0 | 3 |
| DNAJC3 | GNPDA2 | 0.730527 | 3 | 0 | 3 |
| DNAJC3 | ELAC1 | 0.725947 | 3 | 0 | 3 |
| DNAJC3 | VPS36 | 0.72276 | 4 | 0 | 4 |
| DNAJC3 | SCOC | 0.71816 | 3 | 0 | 3 |
| DNAJC3 | NBR1 | 0.717581 | 3 | 0 | 3 |
| DNAJC3 | MEIS2 | 0.713504 | 3 | 0 | 3 |
| DNAJC3 | MTMR9 | 0.712587 | 3 | 0 | 3 |
| DNAJC3 | ZNF33A | 0.70836 | 3 | 0 | 3 |
| DNAJC3 | DCAF10 | 0.702105 | 3 | 0 | 3 |
| DNAJC3 | SHISA5 | 0.701247 | 3 | 0 | 3 |
| DNAJC3 | FBXL3 | 0.701192 | 4 | 0 | 4 |
| DNAJC3 | CDC27 | 0.699394 | 3 | 0 | 3 |
| DNAJC3 | SPG11 | 0.689888 | 3 | 0 | 3 |
| DNAJC3 | TMEM181 | 0.688806 | 4 | 0 | 3 |
| DNAJC3 | SETD7 | 0.686858 | 4 | 0 | 3 |
| DNAJC3 | SPIN4 | 0.686857 | 3 | 0 | 3 |
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