| Full name: centrosomal protein 350 | Alias Symbol: KIAA0480|CAP350 | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 9857 | HGNC ID: HGNC:24238 | Ensembl Gene: ENSG00000135837 | OMIM ID: 617870 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CEP350:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP350 | 9857 | 204373_s_at | 0.1749 | 0.6532 | |
| GSE20347 | CEP350 | 9857 | 204373_s_at | 0.1555 | 0.3591 | |
| GSE23400 | CEP350 | 9857 | 204373_s_at | 0.2007 | 0.0897 | |
| GSE26886 | CEP350 | 9857 | 213165_at | 0.6146 | 0.0071 | |
| GSE29001 | CEP350 | 9857 | 204373_s_at | 0.1139 | 0.6069 | |
| GSE38129 | CEP350 | 9857 | 204373_s_at | 0.1461 | 0.4366 | |
| GSE45670 | CEP350 | 9857 | 213165_at | -0.0264 | 0.8752 | |
| GSE53622 | CEP350 | 9857 | 80638 | 0.0121 | 0.8227 | |
| GSE53624 | CEP350 | 9857 | 80638 | 0.0920 | 0.0428 | |
| GSE63941 | CEP350 | 9857 | 204373_s_at | -0.5643 | 0.0924 | |
| GSE77861 | CEP350 | 9857 | 213165_at | 0.1994 | 0.3895 | |
| GSE97050 | CEP350 | 9857 | A_33_P3244872 | 0.1369 | 0.5036 | |
| SRP007169 | CEP350 | 9857 | RNAseq | 0.8092 | 0.0286 | |
| SRP008496 | CEP350 | 9857 | RNAseq | 0.9364 | 0.0000 | |
| SRP064894 | CEP350 | 9857 | RNAseq | -0.2115 | 0.3282 | |
| SRP133303 | CEP350 | 9857 | RNAseq | 0.1539 | 0.1110 | |
| SRP159526 | CEP350 | 9857 | RNAseq | -0.1060 | 0.7181 | |
| SRP193095 | CEP350 | 9857 | RNAseq | -0.1622 | 0.0111 | |
| SRP219564 | CEP350 | 9857 | RNAseq | -0.0921 | 0.7735 | |
| TCGA | CEP350 | 9857 | RNAseq | -0.0781 | 0.0734 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CEP350 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEP350:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP350 | 9857 | 12 | 0 | 18 | |
| GSE20123 | CEP350 | 9857 | 12 | 0 | 18 | |
| GSE43470 | CEP350 | 9857 | 6 | 1 | 36 | |
| GSE46452 | CEP350 | 9857 | 3 | 1 | 55 | |
| GSE47630 | CEP350 | 9857 | 14 | 0 | 26 | |
| GSE54993 | CEP350 | 9857 | 0 | 6 | 64 | |
| GSE54994 | CEP350 | 9857 | 15 | 0 | 38 | |
| GSE60625 | CEP350 | 9857 | 0 | 0 | 11 | |
| GSE74703 | CEP350 | 9857 | 6 | 1 | 29 | |
| GSE74704 | CEP350 | 9857 | 5 | 0 | 15 | |
| TCGA | CEP350 | 9857 | 40 | 3 | 53 |
Total number of gains: 113; Total number of losses: 12; Total Number of normals: 363.
Somatic mutations of CEP350:
Generating mutation plots.
Highly correlated genes for CEP350:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP350 | LRRC58 | 0.835704 | 3 | 0 | 3 |
| CEP350 | PAK1IP1 | 0.786765 | 3 | 0 | 3 |
| CEP350 | RPP40 | 0.784037 | 3 | 0 | 3 |
| CEP350 | ELAC2 | 0.783603 | 3 | 0 | 3 |
| CEP350 | CSTF2T | 0.780882 | 3 | 0 | 3 |
| CEP350 | KBTBD6 | 0.767813 | 3 | 0 | 3 |
| CEP350 | ESCO1 | 0.761877 | 3 | 0 | 3 |
| CEP350 | GNA13 | 0.75944 | 3 | 0 | 3 |
| CEP350 | CCAR1 | 0.752525 | 3 | 0 | 3 |
| CEP350 | ARID2 | 0.75169 | 4 | 0 | 4 |
| CEP350 | ALDH18A1 | 0.749277 | 3 | 0 | 3 |
| CEP350 | ERVW-1 | 0.748734 | 3 | 0 | 3 |
| CEP350 | SCAMP1 | 0.742699 | 3 | 0 | 3 |
| CEP350 | HMGN1 | 0.739096 | 4 | 0 | 3 |
| CEP350 | RBM4 | 0.736882 | 3 | 0 | 3 |
| CEP350 | ZNF558 | 0.734884 | 4 | 0 | 4 |
| CEP350 | TTC30B | 0.733924 | 3 | 0 | 3 |
| CEP350 | TADA1 | 0.732848 | 4 | 0 | 3 |
| CEP350 | MRPS6 | 0.728311 | 4 | 0 | 4 |
| CEP350 | PTPN4 | 0.71911 | 3 | 0 | 3 |
For details and further investigation, click here
