| Full name: spermatogenesis associated serine rich 2 | Alias Symbol: SPATA10|SCR59|FLJ13117 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 65244 | HGNC ID: HGNC:18650 | Ensembl Gene: ENSG00000123352 | OMIM ID: 611667 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATS2 | 65244 | 222593_s_at | 0.4863 | 0.1909 | |
| GSE20347 | SPATS2 | 65244 | 218324_s_at | 1.1164 | 0.0000 | |
| GSE23400 | SPATS2 | 65244 | 218324_s_at | 0.5650 | 0.0000 | |
| GSE26886 | SPATS2 | 65244 | 222593_s_at | 1.2497 | 0.0001 | |
| GSE29001 | SPATS2 | 65244 | 218324_s_at | 1.0386 | 0.0006 | |
| GSE38129 | SPATS2 | 65244 | 218324_s_at | 1.0863 | 0.0000 | |
| GSE45670 | SPATS2 | 65244 | 222593_s_at | 0.8301 | 0.0001 | |
| GSE53622 | SPATS2 | 65244 | 69636 | 0.6001 | 0.0000 | |
| GSE53624 | SPATS2 | 65244 | 69636 | 0.7747 | 0.0000 | |
| GSE63941 | SPATS2 | 65244 | 222593_s_at | 0.0374 | 0.9143 | |
| GSE77861 | SPATS2 | 65244 | 222593_s_at | 0.7128 | 0.0067 | |
| GSE97050 | SPATS2 | 65244 | A_33_P3808996 | 0.1079 | 0.7905 | |
| SRP007169 | SPATS2 | 65244 | RNAseq | 1.4601 | 0.0004 | |
| SRP008496 | SPATS2 | 65244 | RNAseq | 1.3611 | 0.0000 | |
| SRP064894 | SPATS2 | 65244 | RNAseq | 0.7127 | 0.0006 | |
| SRP133303 | SPATS2 | 65244 | RNAseq | 0.9861 | 0.0000 | |
| SRP159526 | SPATS2 | 65244 | RNAseq | 1.0263 | 0.0035 | |
| SRP193095 | SPATS2 | 65244 | RNAseq | 0.8384 | 0.0000 | |
| SRP219564 | SPATS2 | 65244 | RNAseq | 0.9893 | 0.0012 | |
| TCGA | SPATS2 | 65244 | RNAseq | 0.0745 | 0.1912 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by SPATS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATS2 | 65244 | 6 | 1 | 23 | |
| GSE20123 | SPATS2 | 65244 | 7 | 1 | 22 | |
| GSE43470 | SPATS2 | 65244 | 3 | 1 | 39 | |
| GSE46452 | SPATS2 | 65244 | 8 | 1 | 50 | |
| GSE47630 | SPATS2 | 65244 | 11 | 2 | 27 | |
| GSE54993 | SPATS2 | 65244 | 0 | 5 | 65 | |
| GSE54994 | SPATS2 | 65244 | 4 | 1 | 48 | |
| GSE60625 | SPATS2 | 65244 | 0 | 0 | 11 | |
| GSE74703 | SPATS2 | 65244 | 3 | 1 | 32 | |
| GSE74704 | SPATS2 | 65244 | 5 | 1 | 14 | |
| TCGA | SPATS2 | 65244 | 16 | 11 | 69 |
Total number of gains: 63; Total number of losses: 25; Total Number of normals: 400.
Somatic mutations of SPATS2:
Generating mutation plots.
Highly correlated genes for SPATS2:
Showing top 20/2036 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATS2 | SLC25A29 | 0.785518 | 3 | 0 | 3 |
| SPATS2 | ALKBH6 | 0.772193 | 5 | 0 | 5 |
| SPATS2 | UTP23 | 0.76288 | 5 | 0 | 5 |
| SPATS2 | RAC3 | 0.757683 | 3 | 0 | 3 |
| SPATS2 | DPP9 | 0.755567 | 4 | 0 | 4 |
| SPATS2 | ZC3H18 | 0.753561 | 3 | 0 | 3 |
| SPATS2 | CMTM4 | 0.747209 | 4 | 0 | 3 |
| SPATS2 | BRAT1 | 0.741339 | 7 | 0 | 7 |
| SPATS2 | SRA1 | 0.738101 | 3 | 0 | 3 |
| SPATS2 | SPIRE1 | 0.737977 | 3 | 0 | 3 |
| SPATS2 | KRTCAP2 | 0.737599 | 5 | 0 | 5 |
| SPATS2 | NEK3 | 0.736501 | 3 | 0 | 3 |
| SPATS2 | VPS13B | 0.736141 | 3 | 0 | 3 |
| SPATS2 | MSH6 | 0.735839 | 9 | 0 | 9 |
| SPATS2 | TRIM47 | 0.735428 | 3 | 0 | 3 |
| SPATS2 | HAS3 | 0.734456 | 3 | 0 | 3 |
| SPATS2 | ZBED6 | 0.733276 | 3 | 0 | 3 |
| SPATS2 | U2SURP | 0.72998 | 9 | 0 | 9 |
| SPATS2 | GPR153 | 0.729793 | 5 | 0 | 5 |
| SPATS2 | IPO9 | 0.728507 | 8 | 0 | 8 |
For details and further investigation, click here
