| Full name: elongation factor for RNA polymerase II 3 | Alias Symbol: FLJ22637 | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 80237 | HGNC ID: HGNC:23113 | Ensembl Gene: ENSG00000128886 | OMIM ID: 609885 |
| Drug and gene relationship at DGIdb | |||
Expression of ELL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELL3 | 80237 | 219517_at | -0.7999 | 0.0057 | |
| GSE20347 | ELL3 | 80237 | 219517_at | -0.2940 | 0.1408 | |
| GSE23400 | ELL3 | 80237 | 219517_at | -0.0951 | 0.0385 | |
| GSE26886 | ELL3 | 80237 | 219517_at | -0.0658 | 0.8585 | |
| GSE29001 | ELL3 | 80237 | 219517_at | -0.7490 | 0.0193 | |
| GSE38129 | ELL3 | 80237 | 219517_at | -0.1776 | 0.4561 | |
| GSE45670 | ELL3 | 80237 | 219517_at | -0.2568 | 0.2380 | |
| GSE63941 | ELL3 | 80237 | 219517_at | 0.6625 | 0.3082 | |
| GSE77861 | ELL3 | 80237 | 219517_at | -0.1928 | 0.4195 | |
| GSE97050 | ELL3 | 80237 | A_24_P47988 | 0.1168 | 0.5552 | |
| SRP007169 | ELL3 | 80237 | RNAseq | -1.3599 | 0.0178 | |
| SRP064894 | ELL3 | 80237 | RNAseq | -1.6488 | 0.0000 | |
| SRP133303 | ELL3 | 80237 | RNAseq | -1.2034 | 0.0000 | |
| SRP159526 | ELL3 | 80237 | RNAseq | -1.5302 | 0.0161 | |
| SRP193095 | ELL3 | 80237 | RNAseq | -0.8968 | 0.0000 | |
| SRP219564 | ELL3 | 80237 | RNAseq | -1.7856 | 0.0203 | |
| TCGA | ELL3 | 80237 | RNAseq | -0.0295 | 0.7677 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ELL3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ELL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELL3 | 80237 | 3 | 4 | 23 | |
| GSE20123 | ELL3 | 80237 | 3 | 5 | 22 | |
| GSE43470 | ELL3 | 80237 | 3 | 4 | 36 | |
| GSE46452 | ELL3 | 80237 | 3 | 7 | 49 | |
| GSE47630 | ELL3 | 80237 | 8 | 10 | 22 | |
| GSE54993 | ELL3 | 80237 | 4 | 6 | 60 | |
| GSE54994 | ELL3 | 80237 | 5 | 7 | 41 | |
| GSE60625 | ELL3 | 80237 | 4 | 0 | 7 | |
| GSE74703 | ELL3 | 80237 | 3 | 3 | 30 | |
| GSE74704 | ELL3 | 80237 | 2 | 2 | 16 | |
| TCGA | ELL3 | 80237 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 65; Total Number of normals: 373.
Somatic mutations of ELL3:
Generating mutation plots.
Highly correlated genes for ELL3:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELL3 | DENND4C | 0.764388 | 3 | 0 | 3 |
| ELL3 | TSPAN31 | 0.76341 | 4 | 0 | 4 |
| ELL3 | FIG4 | 0.760377 | 3 | 0 | 3 |
| ELL3 | TMEM218 | 0.760305 | 3 | 0 | 3 |
| ELL3 | CNTNAP3 | 0.751184 | 3 | 0 | 3 |
| ELL3 | P2RY13 | 0.741177 | 3 | 0 | 3 |
| ELL3 | FAM219B | 0.73759 | 3 | 0 | 3 |
| ELL3 | LNPEP | 0.737309 | 3 | 0 | 3 |
| ELL3 | ZNF33A | 0.731637 | 3 | 0 | 3 |
| ELL3 | GSTK1 | 0.727923 | 4 | 0 | 4 |
| ELL3 | BCAP29 | 0.726348 | 4 | 0 | 3 |
| ELL3 | ZMYM5 | 0.72511 | 3 | 0 | 3 |
| ELL3 | PARP4 | 0.712455 | 3 | 0 | 3 |
| ELL3 | C2orf16 | 0.710678 | 4 | 0 | 4 |
| ELL3 | NCOR1 | 0.7103 | 3 | 0 | 3 |
| ELL3 | CCDC154 | 0.702414 | 3 | 0 | 3 |
| ELL3 | LDOC1 | 0.701335 | 4 | 0 | 3 |
| ELL3 | C11orf1 | 0.701253 | 4 | 0 | 4 |
| ELL3 | PNPLA8 | 0.700148 | 3 | 0 | 3 |
| ELL3 | ITGA9 | 0.694919 | 3 | 0 | 3 |
For details and further investigation, click here
