GSTK1

 

Full name: glutathione S-transferase kappa 1 Alias Symbol: GST13
Type: protein-coding gene Cytoband: 7q34
Entrez ID: 373156 HGNC ID: HGNC:16906 Ensembl Gene: ENSG00000197448 OMIM ID: 602321
Drug and gene relationship at DGIdb

 

Expression of GSTK1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GSTK1 373156 217751_at -0.5103 0.1349
GSE20347 GSTK1 373156 217751_at -0.7261 0.0000
GSE23400 GSTK1 373156 217751_at -0.2377 0.0028
GSE26886 GSTK1 373156 217751_at -0.5487 0.0983
GSE29001 GSTK1 373156 217751_at -0.4974 0.0255
GSE38129 GSTK1 373156 217751_at -0.5724 0.0000
GSE45670 GSTK1 373156 217751_at -0.3258 0.0472
GSE53622 GSTK1 373156 18663 -0.6891 0.0000
GSE53624 GSTK1 373156 18663 -0.5877 0.0000
GSE63941 GSTK1 373156 217751_at 0.1906 0.7939
GSE77861 GSTK1 373156 217751_at -0.6497 0.0170
GSE97050 GSTK1 373156 A_33_P3287218 -0.2887 0.3252
SRP007169 GSTK1 373156 RNAseq -1.1084 0.0169
SRP008496 GSTK1 373156 RNAseq -1.1642 0.0000
SRP064894 GSTK1 373156 RNAseq -0.0123 0.9544
SRP133303 GSTK1 373156 RNAseq -0.5483 0.0007
SRP159526 GSTK1 373156 RNAseq -0.9960 0.0038
SRP193095 GSTK1 373156 RNAseq -0.8483 0.0000
SRP219564 GSTK1 373156 RNAseq -0.4416 0.1294
TCGA GSTK1 373156 RNAseq -0.1742 0.0038

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by GSTK1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GSTK1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GSTK1 373156 4 2 24
GSE20123 GSTK1 373156 4 2 24
GSE43470 GSTK1 373156 3 4 36
GSE46452 GSTK1 373156 7 2 50
GSE47630 GSTK1 373156 6 7 27
GSE54993 GSTK1 373156 3 4 63
GSE54994 GSTK1 373156 5 8 40
GSE60625 GSTK1 373156 0 0 11
GSE74703 GSTK1 373156 2 4 30
GSE74704 GSTK1 373156 2 2 16
TCGA GSTK1 373156 28 25 43

Total number of gains: 64; Total number of losses: 60; Total Number of normals: 364.  


 

Somatic mutations of GSTK1:

 

Generating mutation plots.

 

Highly correlated genes for GSTK1:

 

Showing top 20/1276 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GSTK1ZNF5280.824189303
GSTK1ZNF4250.747661404
GSTK1CLEC3B0.745037303
GSTK1C15orf410.734591303
GSTK1GRHPR0.731499606
GSTK1ELL30.727923404
GSTK1PODN0.726795403
GSTK1AFF30.724155303
GSTK1PI160.718968303
GSTK1HSPB60.717934404
GSTK1CHN20.717165303
GSTK1SLC2A40.716998404
GSTK1CCDC70.714295404
GSTK1FBXO100.710558404
GSTK1MRPS330.709893403
GSTK1VPS360.705921606
GSTK1TAAR50.702039303
GSTK1LDB30.700193505
GSTK1TMEM120A0.699126605
GSTK1CYP21A20.696413303

For details and further investigation, click here