| Full name: engrailed homeobox 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 2020 | HGNC ID: HGNC:3343 | Ensembl Gene: ENSG00000164778 | OMIM ID: 131310 |
Expression of EN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EN2 | 2020 | 207060_at | 0.0371 | 0.9153 | |
| GSE20347 | EN2 | 2020 | 207060_at | 0.1584 | 0.0717 | |
| GSE23400 | EN2 | 2020 | 207060_at | 0.0416 | 0.2572 | |
| GSE26886 | EN2 | 2020 | 207060_at | 0.5532 | 0.0346 | |
| GSE29001 | EN2 | 2020 | 207060_at | 0.3539 | 0.2133 | |
| GSE38129 | EN2 | 2020 | 207060_at | 0.4353 | 0.0006 | |
| GSE45670 | EN2 | 2020 | 207060_at | 0.8178 | 0.0065 | |
| GSE53622 | EN2 | 2020 | 111113 | -0.0078 | 0.9347 | |
| GSE53624 | EN2 | 2020 | 111113 | 0.0358 | 0.6747 | |
| GSE63941 | EN2 | 2020 | 207060_at | 1.1415 | 0.1007 | |
| GSE77861 | EN2 | 2020 | 207060_at | 0.3488 | 0.1509 | |
| GSE97050 | EN2 | 2020 | A_23_P134433 | 0.0470 | 0.8539 | |
| SRP133303 | EN2 | 2020 | RNAseq | 2.5689 | 0.0002 | |
| SRP159526 | EN2 | 2020 | RNAseq | 5.7277 | 0.0000 | |
| SRP219564 | EN2 | 2020 | RNAseq | 4.5402 | 0.0000 | |
| TCGA | EN2 | 2020 | RNAseq | 2.9893 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by EN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EN2 | 2020 | 3 | 3 | 24 | |
| GSE20123 | EN2 | 2020 | 2 | 3 | 25 | |
| GSE43470 | EN2 | 2020 | 2 | 5 | 36 | |
| GSE46452 | EN2 | 2020 | 7 | 2 | 50 | |
| GSE47630 | EN2 | 2020 | 6 | 9 | 25 | |
| GSE54993 | EN2 | 2020 | 3 | 3 | 64 | |
| GSE54994 | EN2 | 2020 | 6 | 8 | 39 | |
| GSE60625 | EN2 | 2020 | 0 | 0 | 11 | |
| GSE74703 | EN2 | 2020 | 2 | 4 | 30 | |
| GSE74704 | EN2 | 2020 | 0 | 3 | 17 | |
| TCGA | EN2 | 2020 | 27 | 26 | 43 |
Total number of gains: 58; Total number of losses: 66; Total Number of normals: 364.
Somatic mutations of EN2:
Generating mutation plots.
Highly correlated genes for EN2:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EN2 | CIZ1 | 0.636844 | 3 | 0 | 3 |
| EN2 | AK8 | 0.623639 | 4 | 0 | 4 |
| EN2 | SATB2 | 0.616396 | 4 | 0 | 4 |
| EN2 | UNC5A | 0.61381 | 4 | 0 | 3 |
| EN2 | CCNB3 | 0.608716 | 4 | 0 | 3 |
| EN2 | GLI1 | 0.602615 | 3 | 0 | 3 |
| EN2 | ZNF546 | 0.593869 | 3 | 0 | 3 |
| EN2 | TLN1 | 0.593735 | 3 | 0 | 3 |
| EN2 | MED27 | 0.579534 | 4 | 0 | 3 |
| EN2 | CTRB2 | 0.576523 | 3 | 0 | 3 |
| EN2 | SART3 | 0.575828 | 5 | 0 | 4 |
| EN2 | LINC01015 | 0.574474 | 4 | 0 | 3 |
| EN2 | NXT1 | 0.570371 | 3 | 0 | 3 |
| EN2 | ZNF878 | 0.568868 | 3 | 0 | 3 |
| EN2 | CLDN19 | 0.565596 | 3 | 0 | 3 |
| EN2 | HCK | 0.56057 | 4 | 0 | 3 |
| EN2 | LINC00626 | 0.559632 | 4 | 0 | 3 |
| EN2 | DDN | 0.556462 | 3 | 0 | 3 |
| EN2 | CEP350 | 0.556229 | 4 | 0 | 3 |
| EN2 | PTMS | 0.555488 | 3 | 0 | 3 |
For details and further investigation, click here
