| Full name: CDKN1A interacting zinc finger protein 1 | Alias Symbol: LSFR1|ZNF356 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 25792 | HGNC ID: HGNC:16744 | Ensembl Gene: ENSG00000148337 | OMIM ID: 611420 |
| Drug and gene relationship at DGIdb | |||
Expression of CIZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CIZ1 | 25792 | 205516_x_at | 0.2086 | 0.6093 | |
| GSE20347 | CIZ1 | 25792 | 205516_x_at | 0.0197 | 0.9011 | |
| GSE23400 | CIZ1 | 25792 | 205516_x_at | 0.1966 | 0.0021 | |
| GSE26886 | CIZ1 | 25792 | 205516_x_at | 0.7451 | 0.0003 | |
| GSE29001 | CIZ1 | 25792 | 205516_x_at | 0.0298 | 0.8831 | |
| GSE38129 | CIZ1 | 25792 | 205516_x_at | -0.0756 | 0.4588 | |
| GSE45670 | CIZ1 | 25792 | 213977_s_at | 0.0393 | 0.6960 | |
| GSE53622 | CIZ1 | 25792 | 12353 | 0.0949 | 0.0521 | |
| GSE53624 | CIZ1 | 25792 | 12353 | 0.2790 | 0.0000 | |
| GSE63941 | CIZ1 | 25792 | 205516_x_at | 1.9029 | 0.0001 | |
| GSE77861 | CIZ1 | 25792 | 205516_x_at | 0.2295 | 0.3073 | |
| GSE97050 | CIZ1 | 25792 | A_23_P32223 | -0.0348 | 0.8710 | |
| SRP007169 | CIZ1 | 25792 | RNAseq | 1.1686 | 0.0043 | |
| SRP008496 | CIZ1 | 25792 | RNAseq | 1.2839 | 0.0000 | |
| SRP064894 | CIZ1 | 25792 | RNAseq | 0.4173 | 0.0163 | |
| SRP133303 | CIZ1 | 25792 | RNAseq | 0.1796 | 0.3484 | |
| SRP159526 | CIZ1 | 25792 | RNAseq | 0.3664 | 0.0318 | |
| SRP193095 | CIZ1 | 25792 | RNAseq | 0.2754 | 0.0294 | |
| SRP219564 | CIZ1 | 25792 | RNAseq | 0.0278 | 0.9201 | |
| TCGA | CIZ1 | 25792 | RNAseq | 0.0209 | 0.6355 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CIZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CIZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CIZ1 | 25792 | 6 | 9 | 15 | |
| GSE20123 | CIZ1 | 25792 | 6 | 9 | 15 | |
| GSE43470 | CIZ1 | 25792 | 5 | 7 | 31 | |
| GSE46452 | CIZ1 | 25792 | 6 | 13 | 40 | |
| GSE47630 | CIZ1 | 25792 | 3 | 16 | 21 | |
| GSE54993 | CIZ1 | 25792 | 3 | 3 | 64 | |
| GSE54994 | CIZ1 | 25792 | 11 | 8 | 34 | |
| GSE60625 | CIZ1 | 25792 | 0 | 0 | 11 | |
| GSE74703 | CIZ1 | 25792 | 5 | 5 | 26 | |
| GSE74704 | CIZ1 | 25792 | 3 | 7 | 10 | |
| TCGA | CIZ1 | 25792 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 102; Total Number of normals: 311.
Somatic mutations of CIZ1:
Generating mutation plots.
Highly correlated genes for CIZ1:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CIZ1 | RP9 | 0.735165 | 3 | 0 | 3 |
| CIZ1 | TRAPPC1 | 0.718845 | 4 | 0 | 4 |
| CIZ1 | INTS3 | 0.711397 | 4 | 0 | 4 |
| CIZ1 | ARHGEF16 | 0.708978 | 4 | 0 | 4 |
| CIZ1 | HCFC1R1 | 0.706922 | 5 | 0 | 4 |
| CIZ1 | MRPL24 | 0.700137 | 5 | 0 | 4 |
| CIZ1 | ZNF747 | 0.699389 | 3 | 0 | 3 |
| CIZ1 | GTPBP3 | 0.693311 | 5 | 0 | 5 |
| CIZ1 | SDR39U1 | 0.691652 | 3 | 0 | 3 |
| CIZ1 | HEATR6 | 0.690044 | 3 | 0 | 3 |
| CIZ1 | RILPL1 | 0.687701 | 5 | 0 | 4 |
| CIZ1 | PRR14 | 0.684759 | 4 | 0 | 3 |
| CIZ1 | UCN | 0.684279 | 4 | 0 | 3 |
| CIZ1 | PACS1 | 0.683586 | 4 | 0 | 4 |
| CIZ1 | SARS2 | 0.681765 | 3 | 0 | 3 |
| CIZ1 | DARS2 | 0.680571 | 4 | 0 | 4 |
| CIZ1 | TNK1 | 0.675676 | 5 | 0 | 5 |
| CIZ1 | RPRD2 | 0.674722 | 5 | 0 | 4 |
| CIZ1 | FAM193A | 0.6743 | 3 | 0 | 3 |
| CIZ1 | PTGFRN | 0.674241 | 3 | 0 | 3 |
For details and further investigation, click here
