| Full name: spliceosome associated factor 3, U4/U6 recycling protein | Alias Symbol: KIAA0156|RP11-13G14|TIP110|p110 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 9733 | HGNC ID: HGNC:16860 | Ensembl Gene: ENSG00000075856 | OMIM ID: 611684 |
| Drug and gene relationship at DGIdb | |||
Expression of SART3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SART3 | 9733 | 209127_s_at | 0.3803 | 0.4514 | |
| GSE20347 | SART3 | 9733 | 200069_at | 0.6263 | 0.0000 | |
| GSE23400 | SART3 | 9733 | 209128_s_at | 0.2829 | 0.0000 | |
| GSE26886 | SART3 | 9733 | 200069_at | 0.7872 | 0.0012 | |
| GSE29001 | SART3 | 9733 | 200069_at | 0.5969 | 0.0106 | |
| GSE38129 | SART3 | 9733 | 200069_at | 0.6627 | 0.0000 | |
| GSE45670 | SART3 | 9733 | 209128_s_at | 0.1693 | 0.0383 | |
| GSE53622 | SART3 | 9733 | 85454 | 0.2451 | 0.0000 | |
| GSE53624 | SART3 | 9733 | 85454 | 0.4840 | 0.0000 | |
| GSE63941 | SART3 | 9733 | 200069_at | 0.7668 | 0.0368 | |
| GSE77861 | SART3 | 9733 | 209128_s_at | 0.3299 | 0.0388 | |
| GSE97050 | SART3 | 9733 | A_23_P87664 | 0.1784 | 0.4176 | |
| SRP007169 | SART3 | 9733 | RNAseq | 2.9721 | 0.0000 | |
| SRP008496 | SART3 | 9733 | RNAseq | 2.1908 | 0.0000 | |
| SRP064894 | SART3 | 9733 | RNAseq | 0.1858 | 0.2417 | |
| SRP133303 | SART3 | 9733 | RNAseq | 0.3355 | 0.0345 | |
| SRP159526 | SART3 | 9733 | RNAseq | 0.4840 | 0.0262 | |
| SRP193095 | SART3 | 9733 | RNAseq | 0.3294 | 0.0000 | |
| SRP219564 | SART3 | 9733 | RNAseq | 0.1858 | 0.3829 | |
| TCGA | SART3 | 9733 | RNAseq | 0.0976 | 0.0391 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SART3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SART3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SART3 | 9733 | 5 | 3 | 22 | |
| GSE20123 | SART3 | 9733 | 5 | 3 | 22 | |
| GSE43470 | SART3 | 9733 | 2 | 1 | 40 | |
| GSE46452 | SART3 | 9733 | 9 | 1 | 49 | |
| GSE47630 | SART3 | 9733 | 9 | 1 | 30 | |
| GSE54993 | SART3 | 9733 | 0 | 5 | 65 | |
| GSE54994 | SART3 | 9733 | 4 | 2 | 47 | |
| GSE60625 | SART3 | 9733 | 0 | 0 | 11 | |
| GSE74703 | SART3 | 9733 | 2 | 0 | 34 | |
| GSE74704 | SART3 | 9733 | 2 | 2 | 16 | |
| TCGA | SART3 | 9733 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 28; Total Number of normals: 401.
Somatic mutations of SART3:
Generating mutation plots.
Highly correlated genes for SART3:
Showing top 20/1306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SART3 | RHPN2 | 0.758753 | 3 | 0 | 3 |
| SART3 | TADA1 | 0.735761 | 3 | 0 | 3 |
| SART3 | EIF3C | 0.705569 | 4 | 0 | 3 |
| SART3 | MIEN1 | 0.700498 | 3 | 0 | 3 |
| SART3 | KDM2A | 0.686613 | 3 | 0 | 3 |
| SART3 | PAPLN | 0.682862 | 3 | 0 | 3 |
| SART3 | FTO | 0.682045 | 3 | 0 | 3 |
| SART3 | SPIC | 0.680084 | 3 | 0 | 3 |
| SART3 | MRPL38 | 0.679929 | 3 | 0 | 3 |
| SART3 | ELOF1 | 0.678661 | 4 | 0 | 3 |
| SART3 | WDR81 | 0.678063 | 4 | 0 | 4 |
| SART3 | CDC42BPA | 0.67535 | 3 | 0 | 3 |
| SART3 | CIT | 0.669958 | 3 | 0 | 3 |
| SART3 | CHD4 | 0.669517 | 6 | 0 | 5 |
| SART3 | LRRC47 | 0.667173 | 4 | 0 | 3 |
| SART3 | TMEM69 | 0.66662 | 4 | 0 | 4 |
| SART3 | RBM26 | 0.663988 | 4 | 0 | 3 |
| SART3 | RBM14 | 0.6626 | 7 | 0 | 7 |
| SART3 | FAM117B | 0.662029 | 3 | 0 | 3 |
| SART3 | SRRT | 0.661879 | 12 | 0 | 10 |
For details and further investigation, click here
