| Full name: guanosine monophosphate reductase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 2766 | HGNC ID: HGNC:4376 | Ensembl Gene: ENSG00000137198 | OMIM ID: 139265 |
| Drug and gene relationship at DGIdb | |||
Expression of GMPR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GMPR | 2766 | 204187_at | -0.1028 | 0.9076 | |
| GSE20347 | GMPR | 2766 | 204187_at | 0.0723 | 0.5141 | |
| GSE23400 | GMPR | 2766 | 204187_at | -0.0348 | 0.4218 | |
| GSE26886 | GMPR | 2766 | 204187_at | 0.8580 | 0.0008 | |
| GSE29001 | GMPR | 2766 | 204187_at | 0.2598 | 0.4708 | |
| GSE38129 | GMPR | 2766 | 204187_at | -0.2089 | 0.3862 | |
| GSE45670 | GMPR | 2766 | 204187_at | -0.1984 | 0.4177 | |
| GSE53622 | GMPR | 2766 | 6879 | -0.2938 | 0.0913 | |
| GSE53624 | GMPR | 2766 | 6879 | 0.2264 | 0.0721 | |
| GSE63941 | GMPR | 2766 | 204187_at | -1.6237 | 0.0006 | |
| GSE77861 | GMPR | 2766 | 204187_at | 0.0061 | 0.9647 | |
| GSE97050 | GMPR | 2766 | A_24_P277657 | -0.9920 | 0.1569 | |
| SRP064894 | GMPR | 2766 | RNAseq | -0.0601 | 0.8956 | |
| SRP133303 | GMPR | 2766 | RNAseq | -0.6593 | 0.0582 | |
| SRP159526 | GMPR | 2766 | RNAseq | 1.1693 | 0.0653 | |
| SRP219564 | GMPR | 2766 | RNAseq | 0.4431 | 0.6068 | |
| TCGA | GMPR | 2766 | RNAseq | -1.1595 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GMPR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GMPR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GMPR | 2766 | 3 | 5 | 22 | |
| GSE20123 | GMPR | 2766 | 3 | 5 | 22 | |
| GSE43470 | GMPR | 2766 | 8 | 0 | 35 | |
| GSE46452 | GMPR | 2766 | 1 | 10 | 48 | |
| GSE47630 | GMPR | 2766 | 7 | 7 | 26 | |
| GSE54993 | GMPR | 2766 | 1 | 1 | 68 | |
| GSE54994 | GMPR | 2766 | 10 | 3 | 40 | |
| GSE60625 | GMPR | 2766 | 0 | 1 | 10 | |
| GSE74703 | GMPR | 2766 | 7 | 0 | 29 | |
| GSE74704 | GMPR | 2766 | 2 | 2 | 16 | |
| TCGA | GMPR | 2766 | 16 | 26 | 54 |
Total number of gains: 58; Total number of losses: 60; Total Number of normals: 370.
Somatic mutations of GMPR:
Generating mutation plots.
Highly correlated genes for GMPR:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GMPR | CACNA1C | 0.802152 | 3 | 0 | 3 |
| GMPR | FLNC | 0.797151 | 4 | 0 | 4 |
| GMPR | PNCK | 0.790635 | 3 | 0 | 3 |
| GMPR | SGCA | 0.7868 | 3 | 0 | 3 |
| GMPR | IL33 | 0.781744 | 3 | 0 | 3 |
| GMPR | SMTN | 0.770572 | 3 | 0 | 3 |
| GMPR | DMPK | 0.767566 | 3 | 0 | 3 |
| GMPR | CLMP | 0.759832 | 3 | 0 | 3 |
| GMPR | SH3RF3 | 0.758951 | 3 | 0 | 3 |
| GMPR | EID3 | 0.758463 | 3 | 0 | 3 |
| GMPR | PALLD | 0.749668 | 4 | 0 | 4 |
| GMPR | NEXN | 0.749065 | 3 | 0 | 3 |
| GMPR | LMOD1 | 0.742519 | 4 | 0 | 4 |
| GMPR | SLC39A13 | 0.740315 | 4 | 0 | 4 |
| GMPR | ST6GALNAC6 | 0.738833 | 3 | 0 | 3 |
| GMPR | CBX6 | 0.735739 | 4 | 0 | 4 |
| GMPR | SYNM | 0.728469 | 3 | 0 | 3 |
| GMPR | HERC2 | 0.726477 | 3 | 0 | 3 |
| GMPR | SCAI | 0.726169 | 3 | 0 | 3 |
| GMPR | RASSF3 | 0.724946 | 3 | 0 | 3 |
For details and further investigation, click here
