| Full name: Ras association domain family member 8 | Alias Symbol: HoJ-1 | ||
| Type: protein-coding gene | Cytoband: 12p12.1 | ||
| Entrez ID: 11228 | HGNC ID: HGNC:13232 | Ensembl Gene: ENSG00000123094 | OMIM ID: 608231 |
| Drug and gene relationship at DGIdb | |||
Expression of RASSF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASSF8 | 11228 | 225946_at | -0.2175 | 0.8338 | |
| GSE20347 | RASSF8 | 11228 | 207754_at | 0.0945 | 0.0491 | |
| GSE23400 | RASSF8 | 11228 | 207754_at | -0.0154 | 0.5338 | |
| GSE26886 | RASSF8 | 11228 | 225946_at | 1.9119 | 0.0004 | |
| GSE29001 | RASSF8 | 11228 | 207754_at | 0.0034 | 0.9787 | |
| GSE38129 | RASSF8 | 11228 | 207754_at | -0.1227 | 0.3973 | |
| GSE45670 | RASSF8 | 11228 | 225946_at | -1.1532 | 0.0189 | |
| GSE53622 | RASSF8 | 11228 | 76474 | 0.4969 | 0.0011 | |
| GSE53624 | RASSF8 | 11228 | 73304 | -0.9780 | 0.0000 | |
| GSE63941 | RASSF8 | 11228 | 225946_at | -3.0949 | 0.0009 | |
| GSE77861 | RASSF8 | 11228 | 207754_at | 0.0723 | 0.5438 | |
| GSE97050 | RASSF8 | 11228 | A_24_P78556 | -0.2101 | 0.5574 | |
| SRP007169 | RASSF8 | 11228 | RNAseq | 2.2104 | 0.0000 | |
| SRP008496 | RASSF8 | 11228 | RNAseq | 3.2030 | 0.0000 | |
| SRP064894 | RASSF8 | 11228 | RNAseq | 0.4948 | 0.0987 | |
| SRP133303 | RASSF8 | 11228 | RNAseq | 0.6247 | 0.0005 | |
| SRP159526 | RASSF8 | 11228 | RNAseq | 0.5080 | 0.0513 | |
| SRP193095 | RASSF8 | 11228 | RNAseq | 1.1541 | 0.0000 | |
| SRP219564 | RASSF8 | 11228 | RNAseq | 0.3880 | 0.4880 | |
| TCGA | RASSF8 | 11228 | RNAseq | -0.1193 | 0.3707 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by RASSF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASSF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASSF8 | 11228 | 10 | 1 | 19 | |
| GSE20123 | RASSF8 | 11228 | 10 | 1 | 19 | |
| GSE43470 | RASSF8 | 11228 | 9 | 4 | 30 | |
| GSE46452 | RASSF8 | 11228 | 10 | 1 | 48 | |
| GSE47630 | RASSF8 | 11228 | 15 | 0 | 25 | |
| GSE54993 | RASSF8 | 11228 | 0 | 9 | 61 | |
| GSE54994 | RASSF8 | 11228 | 11 | 2 | 40 | |
| GSE60625 | RASSF8 | 11228 | 0 | 1 | 10 | |
| GSE74703 | RASSF8 | 11228 | 9 | 3 | 24 | |
| GSE74704 | RASSF8 | 11228 | 6 | 1 | 13 | |
| TCGA | RASSF8 | 11228 | 44 | 5 | 47 |
Total number of gains: 124; Total number of losses: 28; Total Number of normals: 336.
Somatic mutations of RASSF8:
Generating mutation plots.
Highly correlated genes for RASSF8:
Showing top 20/958 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASSF8 | MYOM2 | 0.784588 | 3 | 0 | 3 |
| RASSF8 | SYNC | 0.770518 | 5 | 0 | 5 |
| RASSF8 | MYADM | 0.762639 | 4 | 0 | 4 |
| RASSF8 | ANTXR2 | 0.757974 | 6 | 0 | 6 |
| RASSF8 | PKD2 | 0.75488 | 7 | 0 | 7 |
| RASSF8 | NFIC | 0.748219 | 3 | 0 | 3 |
| RASSF8 | ING1 | 0.746873 | 3 | 0 | 3 |
| RASSF8 | DNM3OS | 0.738896 | 3 | 0 | 3 |
| RASSF8 | CNRIP1 | 0.735963 | 4 | 0 | 4 |
| RASSF8 | RFTN1 | 0.735832 | 7 | 0 | 7 |
| RASSF8 | LIX1L | 0.735614 | 6 | 0 | 6 |
| RASSF8 | SGIP1 | 0.734465 | 5 | 0 | 5 |
| RASSF8 | VCL | 0.731669 | 5 | 0 | 5 |
| RASSF8 | FBN1 | 0.727176 | 6 | 0 | 6 |
| RASSF8 | BICC1 | 0.725826 | 6 | 0 | 6 |
| RASSF8 | CLMP | 0.722537 | 6 | 0 | 6 |
| RASSF8 | CD36 | 0.722209 | 3 | 0 | 3 |
| RASSF8 | STON1 | 0.722053 | 7 | 0 | 7 |
| RASSF8 | MAOB | 0.721192 | 3 | 0 | 3 |
| RASSF8 | SSPN | 0.721057 | 7 | 0 | 7 |
For details and further investigation, click here
