| Full name: epidermal growth factor receptor pathway substrate 15 like 1 | Alias Symbol: eps15R | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 58513 | HGNC ID: HGNC:24634 | Ensembl Gene: ENSG00000127527 | OMIM ID: 616826 |
| Drug and gene relationship at DGIdb | |||
Expression of EPS15L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPS15L1 | 58513 | 231926_at | 0.0045 | 0.9966 | |
| GSE20347 | EPS15L1 | 58513 | 221056_x_at | -0.2723 | 0.0031 | |
| GSE23400 | EPS15L1 | 58513 | 221056_x_at | -0.2087 | 0.0000 | |
| GSE26886 | EPS15L1 | 58513 | 231926_at | -1.5649 | 0.0000 | |
| GSE29001 | EPS15L1 | 58513 | 222113_s_at | -0.0229 | 0.9698 | |
| GSE38129 | EPS15L1 | 58513 | 221056_x_at | -0.3570 | 0.0011 | |
| GSE45670 | EPS15L1 | 58513 | 231926_at | -0.2088 | 0.3166 | |
| GSE53622 | EPS15L1 | 58513 | 707 | -0.3630 | 0.0000 | |
| GSE53624 | EPS15L1 | 58513 | 707 | -0.0762 | 0.3074 | |
| GSE63941 | EPS15L1 | 58513 | 232438_at | 0.5471 | 0.0171 | |
| GSE77861 | EPS15L1 | 58513 | 232438_at | -0.0253 | 0.8984 | |
| GSE97050 | EPS15L1 | 58513 | A_33_P3350828 | 0.0127 | 0.9626 | |
| SRP007169 | EPS15L1 | 58513 | RNAseq | -0.6058 | 0.0579 | |
| SRP008496 | EPS15L1 | 58513 | RNAseq | -0.7011 | 0.0021 | |
| SRP064894 | EPS15L1 | 58513 | RNAseq | -0.2934 | 0.0446 | |
| SRP133303 | EPS15L1 | 58513 | RNAseq | -0.3967 | 0.0007 | |
| SRP159526 | EPS15L1 | 58513 | RNAseq | -0.2331 | 0.1318 | |
| SRP193095 | EPS15L1 | 58513 | RNAseq | -0.2145 | 0.1738 | |
| SRP219564 | EPS15L1 | 58513 | RNAseq | 0.0725 | 0.7766 | |
| TCGA | EPS15L1 | 58513 | RNAseq | 0.0412 | 0.3925 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EPS15L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPS15L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPS15L1 | 58513 | 4 | 3 | 23 | |
| GSE20123 | EPS15L1 | 58513 | 3 | 2 | 25 | |
| GSE43470 | EPS15L1 | 58513 | 2 | 6 | 35 | |
| GSE46452 | EPS15L1 | 58513 | 47 | 1 | 11 | |
| GSE47630 | EPS15L1 | 58513 | 4 | 8 | 28 | |
| GSE54993 | EPS15L1 | 58513 | 15 | 4 | 51 | |
| GSE54994 | EPS15L1 | 58513 | 6 | 14 | 33 | |
| GSE60625 | EPS15L1 | 58513 | 9 | 0 | 2 | |
| GSE74703 | EPS15L1 | 58513 | 2 | 4 | 30 | |
| GSE74704 | EPS15L1 | 58513 | 0 | 1 | 19 | |
| TCGA | EPS15L1 | 58513 | 18 | 9 | 69 |
Total number of gains: 110; Total number of losses: 52; Total Number of normals: 326.
Somatic mutations of EPS15L1:
Generating mutation plots.
Highly correlated genes for EPS15L1:
Showing top 20/879 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPS15L1 | RAB35 | 0.818051 | 4 | 0 | 4 |
| EPS15L1 | BTBD2 | 0.785249 | 3 | 0 | 3 |
| EPS15L1 | CHCHD1 | 0.768863 | 4 | 0 | 4 |
| EPS15L1 | XPNPEP1 | 0.768256 | 3 | 0 | 3 |
| EPS15L1 | KCTD15 | 0.760016 | 3 | 0 | 3 |
| EPS15L1 | TMEM214 | 0.759094 | 3 | 0 | 3 |
| EPS15L1 | MRPL38 | 0.757368 | 3 | 0 | 3 |
| EPS15L1 | MUC15 | 0.732581 | 3 | 0 | 3 |
| EPS15L1 | EPN1 | 0.729858 | 4 | 0 | 4 |
| EPS15L1 | CEP85 | 0.722312 | 3 | 0 | 3 |
| EPS15L1 | PRPF38A | 0.722056 | 4 | 0 | 4 |
| EPS15L1 | VPS25 | 0.713089 | 4 | 0 | 4 |
| EPS15L1 | OXNAD1 | 0.711272 | 4 | 0 | 4 |
| EPS15L1 | NPFF | 0.71058 | 3 | 0 | 3 |
| EPS15L1 | LEMD2 | 0.707614 | 3 | 0 | 3 |
| EPS15L1 | CYSRT1 | 0.699417 | 3 | 0 | 3 |
| EPS15L1 | HIPK1 | 0.693189 | 5 | 0 | 4 |
| EPS15L1 | FLG-AS1 | 0.692832 | 3 | 0 | 3 |
| EPS15L1 | KLHL36 | 0.692191 | 3 | 0 | 3 |
| EPS15L1 | FEM1A | 0.691419 | 3 | 0 | 3 |
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