| Full name: mucin 15, cell surface associated | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p14.3 | ||
| Entrez ID: 143662 | HGNC ID: HGNC:14956 | Ensembl Gene: ENSG00000169550 | OMIM ID: 608566 |
| Drug and gene relationship at DGIdb | |||
Expression of MUC15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MUC15 | 143662 | 227238_at | -2.3177 | 0.1270 | |
| GSE26886 | MUC15 | 143662 | 227238_at | -4.8369 | 0.0000 | |
| GSE45670 | MUC15 | 143662 | 227238_at | -1.2303 | 0.0156 | |
| GSE53622 | MUC15 | 143662 | 4109 | -3.2445 | 0.0000 | |
| GSE53624 | MUC15 | 143662 | 4109 | -3.3531 | 0.0000 | |
| GSE63941 | MUC15 | 143662 | 227241_at | 0.8083 | 0.5058 | |
| GSE77861 | MUC15 | 143662 | 227238_at | -1.7087 | 0.0316 | |
| GSE97050 | MUC15 | 143662 | A_23_P24332 | -0.8751 | 0.2079 | |
| SRP007169 | MUC15 | 143662 | RNAseq | -4.2008 | 0.0000 | |
| SRP008496 | MUC15 | 143662 | RNAseq | -3.3649 | 0.0000 | |
| SRP064894 | MUC15 | 143662 | RNAseq | -3.4194 | 0.0000 | |
| SRP133303 | MUC15 | 143662 | RNAseq | -3.0174 | 0.0000 | |
| SRP159526 | MUC15 | 143662 | RNAseq | -3.3952 | 0.0016 | |
| SRP219564 | MUC15 | 143662 | RNAseq | -3.8781 | 0.0000 | |
| TCGA | MUC15 | 143662 | RNAseq | -0.0204 | 0.9576 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by MUC15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MUC15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MUC15 | 143662 | 1 | 9 | 20 | |
| GSE20123 | MUC15 | 143662 | 1 | 8 | 21 | |
| GSE43470 | MUC15 | 143662 | 1 | 5 | 37 | |
| GSE46452 | MUC15 | 143662 | 7 | 5 | 47 | |
| GSE47630 | MUC15 | 143662 | 3 | 10 | 27 | |
| GSE54993 | MUC15 | 143662 | 3 | 0 | 67 | |
| GSE54994 | MUC15 | 143662 | 4 | 11 | 38 | |
| GSE60625 | MUC15 | 143662 | 0 | 0 | 11 | |
| GSE74703 | MUC15 | 143662 | 1 | 3 | 32 | |
| GSE74704 | MUC15 | 143662 | 0 | 8 | 12 | |
| TCGA | MUC15 | 143662 | 12 | 25 | 59 |
Total number of gains: 33; Total number of losses: 84; Total Number of normals: 371.
Somatic mutations of MUC15:
Generating mutation plots.
Highly correlated genes for MUC15:
Showing top 20/1478 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MUC15 | VSIG10L | 0.852418 | 7 | 0 | 7 |
| MUC15 | CLCA4 | 0.84719 | 7 | 0 | 7 |
| MUC15 | CAPN14 | 0.844823 | 6 | 0 | 6 |
| MUC15 | SPRR3 | 0.839313 | 7 | 0 | 7 |
| MUC15 | SLURP1 | 0.8386 | 7 | 0 | 7 |
| MUC15 | TMPRSS11B | 0.837134 | 7 | 0 | 7 |
| MUC15 | RANBP9 | 0.835898 | 6 | 0 | 6 |
| MUC15 | A2ML1 | 0.835235 | 7 | 0 | 7 |
| MUC15 | TMPRSS11E | 0.834526 | 7 | 0 | 7 |
| MUC15 | SCNN1B | 0.832901 | 7 | 0 | 7 |
| MUC15 | FMO2 | 0.831004 | 6 | 0 | 6 |
| MUC15 | MGLL | 0.829007 | 6 | 0 | 6 |
| MUC15 | SLC16A6 | 0.828757 | 6 | 0 | 6 |
| MUC15 | LYNX1 | 0.828191 | 7 | 0 | 7 |
| MUC15 | RAB10 | 0.828143 | 7 | 0 | 7 |
| MUC15 | EHD3 | 0.826853 | 6 | 0 | 6 |
| MUC15 | GDPD3 | 0.826327 | 8 | 0 | 8 |
| MUC15 | NAGK | 0.824679 | 6 | 0 | 6 |
| MUC15 | SPNS2 | 0.822432 | 5 | 0 | 5 |
| MUC15 | KRT13 | 0.822062 | 7 | 0 | 7 |
For details and further investigation, click here
